Hamartomas are congenital malformations composed of a heterotopic mass of neurosecretory neurons, fiber bundles and glial cells, frequently associated with true precocious puberty, usually occurring before 3 years of age. They can be associated with laughter or generalized tonic-clonic seizures, mental retardation, behavioral disturbances and dysmorphic syndromes. The occurrence of seizures is uncommon when the mass diameter is less than 10 mm, whereas a larger mass is associated with a high risk of seizures.
Hamartoma, Pituitary
Patti, G.;Morana, G.;Di Iorgi, N.;Maghnie, M.
2018-01-01
Abstract
Hamartomas are congenital malformations composed of a heterotopic mass of neurosecretory neurons, fiber bundles and glial cells, frequently associated with true precocious puberty, usually occurring before 3 years of age. They can be associated with laughter or generalized tonic-clonic seizures, mental retardation, behavioral disturbances and dysmorphic syndromes. The occurrence of seizures is uncommon when the mass diameter is less than 10 mm, whereas a larger mass is associated with a high risk of seizures.
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