COMPOSITE BASED ON POLYVINYL ALCOHOL, CHITOSAN, CAFFEINE, AND POLYDOPAMINE FOR WOUND HEALING

The composite based on polyvinyl alcohol (PVA), chitosan (CS), and caffeine (Caff) has been prepared. PVA is a well-known synthetic polymer, and it has applications in wound dressings due to its ease of processing. Chitosan has a key role in hemostasis, and hemostasis is the prominent phase of wound healing. Caffeine also has applications in diabetic wounds due to its anti-oxidant properties. After the preparation of the composite (PVA/CS/Caff) the addition of polydopamine (PDA) has been provided and the effect of PDA on the composite properties has been observed. It is commonly known that PDA has the well-established role of surface coatings, and it has an effective role in wound healing. The presence of the individual components was analysed by using the Fourier transform infrared spectroscopy (FTIR). Microscopic studies have been conducted to visualize the polymeric films. The mechanical properties of the polymeric films have been tested utilizing the mechanical properties testing machine (Zwick & Roell 0.5). The results of mechanical properties have been analyzed by utilization of the testXpert II 2017 computer program. It was found that the addition of PDA modified the properties of the PVA/CS/Caff composite.