IRIS
FLORIO, TULLIO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 37.812
AS - Asia 4.106
NA - Nord America 3.707
Continente sconosciuto - Info sul continente non disponibili 884
SA - Sud America 394
AF - Africa 64
OC - Oceania 10
Totale 46.977
Salva come PNG Salva come JPEG
Nazione #
IT - Italia 37.124
US - Stati Uniti d'America 3.466
SG - Singapore 1.646
CN - Cina 1.080
VN - Vietnam 650
BD - Bangladesh 318
FR - Francia 315
BR - Brasile 234
HK - Hong Kong 147
CA - Canada 84
DE - Germania 79
FI - Finlandia 64
AR - Argentina 62
MX - Messico 52
GB - Regno Unito 49
JP - Giappone 38
IQ - Iraq 32
IN - India 31
CH - Svizzera 27
ID - Indonesia 27
CO - Colombia 26
JM - Giamaica 24
EC - Ecuador 22
NL - Olanda 19
PK - Pakistan 18
HN - Honduras 16
IE - Irlanda 16
PL - Polonia 16
CR - Costa Rica 15
ES - Italia 15
ZA - Sudafrica 15
RU - Federazione Russa 14
UA - Ucraina 14
CL - Cile 13
PH - Filippine 13
KR - Corea 12
TR - Turchia 12
VE - Venezuela 12
KE - Kenya 10
GT - Guatemala 9
SV - El Salvador 9
TH - Thailandia 9
AU - Australia 8
MA - Marocco 8
UY - Uruguay 8
JO - Giordania 7
PE - Perù 7
TW - Taiwan 7
AT - Austria 6
BE - Belgio 6
KZ - Kazakistan 6
PR - Porto Rico 6
SC - Seychelles 6
BO - Bolivia 5
NI - Nicaragua 5
NP - Nepal 5
PY - Paraguay 5
RO - Romania 5
RS - Serbia 5
SA - Arabia Saudita 5
SE - Svezia 5
UZ - Uzbekistan 5
AZ - Azerbaigian 4
BZ - Belize 4
DK - Danimarca 4
DZ - Algeria 4
LT - Lituania 4
SY - Repubblica araba siriana 4
TT - Trinidad e Tobago 4
AL - Albania 3
BH - Bahrain 3
CY - Cipro 3
EG - Egitto 3
HU - Ungheria 3
IL - Israele 3
KG - Kirghizistan 3
LV - Lettonia 3
MY - Malesia 3
OM - Oman 3
TN - Tunisia 3
AE - Emirati Arabi Uniti 2
BA - Bosnia-Erzegovina 2
BB - Barbados 2
BY - Bielorussia 2
GP - Guadalupe 2
GR - Grecia 2
HR - Croazia 2
LB - Libano 2
MQ - Martinica 2
NG - Nigeria 2
PA - Panama 2
PT - Portogallo 2
SI - Slovenia 2
TZ - Tanzania 2
AO - Angola 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
BQ - ???statistics.table.value.countryCode.BQ??? 1
BS - Bahamas 1
CI - Costa d'Avorio 1
Totale 46.069
Salva come PNG Salva come JPEG
Città #
Genova 20.899
Genoa 10.452
Vado Ligure 2.756
Rapallo 2.540
San Jose 874
Singapore 778
Ashburn 403
Lauterbourg 281
Ho Chi Minh City 197
Beijing 187
Council Bluffs 164
Hanoi 145
New York 141
Hong Kong 140
Santa Clara 97
Bordighera 66
Frankfurt am Main 62
Helsinki 58
Los Angeles 56
Chicago 45
Milan 45
Rome 41
Haiphong 38
Tokyo 34
Mexico City 33
St Louis 33
Tianjin 32
São Paulo 27
Dallas 25
Da Nang 22
Phoenix 21
Atlanta 20
Boardman 20
Buffalo 20
Zurich 20
Brooklyn 17
Dublin 16
Florence 15
Miami 15
Montreal 14
Warsaw 14
Amsterdam 13
Hải Dương 13
Naples 13
Orem 13
Palermo 13
San José 13
Tampa 13
Nashville 12
Princeton 12
The Bronx 12
Charlotte 11
City of London 11
Jacksonville 11
Philadelphia 11
Biên Hòa 10
Des Moines 10
Houston 10
Las Vegas 10
Memphis 10
Ninh Bình 10
Queens 10
Quito 10
Rio de Janeiro 10
Shanghai 10
Baghdad 9
Bologna 9
Detroit 9
Nairobi 9
Pittsburgh 9
San Francisco 9
Curitiba 8
Guangzhou 8
Jakarta 8
London 8
Louisville 8
Medellín 8
Padua 8
San Pedro Sula 8
Seattle 8
Thái Bình 8
Toronto 8
Turin 8
Brasília 7
Guatemala City 7
Madrid 7
Montevideo 7
Newark 7
Nha Trang 7
San Salvador 7
Santiago 7
Belo Horizonte 6
Bogotá 6
Buenos Aires 6
Can Tho 6
Cardiff 6
Denver 6
Kingston 6
Nuremberg 6
Poplar 6
Totale 41.394
Salva come PNG Salva come JPEG
Nome #
NDM29, a RNA polymerase III-dependent non coding RNA, promotes amyloidogenic processing of APP and amyloid β secretion 280
Biomimetic hybrid vesicles for boron neutron capture therapy of glioblastoma 274
Development of an Injectable Slow-Release Metformin Formulation and Evaluation of Its Potential Antitumor Effects 268
Characterization of the pro-apoptotic intracellular mechanisms induced by a toxic conformer of the recombinant human prion protein fragment 90-231 265
Amyloid precursor protein modulates ERK1/2 signaling 259
Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells 257
17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease 256
New molecules and old drugs as emerging approaches to selectively target human glioblastoma cancer stem cells 246
Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets. 246
The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma 245
Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors 241
Anti-proliferative and anti-secretory effects of everolimus on human pancreatic neuroendocrine tumors primary cultures: is there any benefit from combination with somatostatin analogs? 239
Calcium binding promotes Prion Protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure 238
Amyloid precursor protein and Presenilin 1 interaction studied by FRET in human H4 cells. 231
Human glioblastoma-derived cell membrane nanovesicles: a novel, cell-specific strategy for boron neutron capture therapy of brain tumors 228
The inhibition of 45A ncRNA expression reduces tumor formation, affecting tumor nodules compactness and metastatic potential in neuroblastoma cells 227
A critical concentration of N-terminal pyroglutamylated amyloid beta drives the misfolding of Ab1-42 into more toxic aggregates 227
Peptide Receptor Targeting in Cancer: The Somatostatin Paradigm 226
In vitro and in vivo characterization of stem-like cells from canine osteosarcoma and assessment of drug sensitivity 226
Amino-terminally truncated prion protein PrP90-231 induces microglial activation in vitro 224
Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis 224
Apoptotic cell death and impairment of L-type voltage sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126 222
Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells 219
Dual modulation of ERK1/2 and p38 MAP kinase activities induced by minocycline reverses the neurotoxic effects of the prion protein fragment 90-231 217
Protective effects of some creatine derivatives in brain tissue anoxia. 217
Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity. 216
SDF1 controls pituitary cell proliferation through the activation of ERK1/2 and the Ca2+-dependent cytosolic tyrosine kinase, Pyk2. 212
Adiponectin as Novel Regulator of Cell Proliferation in Human Glioblastoma 212
An Alu-like RNA promotes cell differentiation and reduces malignancy of human neuroblastoma cells. 208
An interaction between hepatocyte growth factor and its receptor (c-MET) prolongs the survival of chronic lymphocytic leukemic cells through STAT3 phosphorylation: a potential role of mesenchymal cells in the disease 205
Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells 205
Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death 205
Autophagy Activator Drugs: A New Opportunity in Neuroprotection from Misfolded Protein Toxicity 204
In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors 204
Chemokines and chemokine receptors: New actors in neuroendocrine regulations 203
Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current 202
Complexity and Selectivity of γ-Secretase Cleavage on Multiple Substrates: Consequences in Alzheimer's Disease and Cancer 202
A Novel Collection of snRNA-Like Promoters with Tissue-Specific Transcription Properties 202
Differential toxicity, conformation and morphology of typical initial aggregation states of Aβ1-42 and Aβpy3-42 beta-amyloids 202
Amyloid precursor protein and presenilin involvement in cell signaling 201
Inhibition of chloride intracellular channel 1 (CLIC1) as biguanide class-effect to impair human glioblastoma stem cell viability 201
A novel snRNA-like transcript affects amyloidogenesis and cell cycle progression through perturbation of Fe65L1 (APBB2) alternative splicing. 199
Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90–231 Neurotoxic Effects in Cerebellar Granule Neurons 199
Co-Administration of Fendiline Hydrochloride Enhances Chemotherapeutic Efficacy of Cisplatin in Neuroblastoma Treatment 199
Proteostasis unbalance in prion diseases: mechanisms of neurodegeneration and therapeutic targets 198
Endometrial stem cells and human reproductive failure 197
Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic 196
Perhexiline maleate enhances antitumor efficacy of cisplatin in neuroblastoma by inducing over-expression of NDM29 ncRNA 195
Drug-repositioning opportunities for cancer therapy: Novel molecular targets for known compounds 195
Different structural stability and toxicity of PrPARR and PrPARQ sheep prion protein variants 194
Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA 193
Drug design strategies focusing on the CXCR4/CXCR7/CXCL12 pathway in leukemia and lymphoma 193
Down-regulation of 21A Alu RNA as a tool to boost proliferation maintaining the tissue regeneration potential of progenitor cells 193
Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives 192
Receptor tyrosine kinase inhibitors and cytotoxic drugs affect pleural mesothelioma cell proliferation: insight into EGFR and ERK1/2 as antitumor targets 191
Glioblastoma cancer stem cells: response to epidermal growth factor receptor kinase inhibitors 190
The somatostatin analogue octreotide confers sensitivity to rapamycin treatment on pituitary tumor cells 189
Phenotypical and Pharmacological Characterization of Stem-Like Cells in Human Pituitary Adenomas 189
Balance between somatostatin and D2 receptor expression drives TSH-secreting adenoma response to somatostatin analogs and dopastatins 188
Chemokines and their receptors in the CNS: expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation 187
Biological and Biochemical Basis of the Differential Efficacy of First and Second Generation Somatostatin Receptor Ligands in Neuroendocrine Neoplasms 187
b25-35 alters calcium homeostasis and induces neurotoxicity in cerebellar granule cells 186
Canine osteosarcoma cell lines contain stem-like cancer cells: Biological and pharmacological characterization 186
Emerging targets in pituitary adenomas: role of the CXCL12/CXCR4-R7 system 185
Differential efficacy of SSTR1, 2 and 5 agonists in the inhibition of C6 glioma growth in nude mice 185
Effects of Prion Protein on Aβ42 and Pyroglutamate-Modified AβpΕ3-42 Oligomerization and Toxicity 184
ACTIVATION OF AUTOPHAGY PATHWAY AS NEUROPROTECTIVE MECHANISM AGAINST AMYLOIDOGENIC PRION PEPTIDE 184
ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation 182
Different response of human glioma tumor-initiating cells to EGFR kinase inhibitors. 180
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction 180
Patient-derived xenograft in zebrafish embryos: a new platform for translational research in neuroendocrine tumors 180
A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis 180
Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures 180
Novel celecoxib analogues inhibit glial production of prostaglandinE2, nitric oxide, and oxygen radicals reverting the neuroinflammatoryresponses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide 180
Chemokine stromal cell-derived factor 1α induces proliferation and growth hormone release in GH4C1 rat pituitary adenoma cell line through multiple intracellular signals 179
A. novel mechanism for the melatonin inhibition of testosterone secretion by rat Leydig cells: reduction of GnRH-induced cytosolic Ca2+ rise 179
Molecular pharmacology of malignant pleural mesothelioma: Challenges and perspectives from preclinical and clinical studies 178
SOMATOSTATIN ACTIVATION OF MITOGEN ACTIVATED PROTEIN KINASE VIA SOMATOSTATIN RECEPTOR 1 (SSTR1) 177
The chemokine SDF1/CXCL12: a novel autocrine/paracrine factor involved in pituitary adenoma development 177
Neuroblastoma: Inhibition by Alu-Like RNA 177
Minimalist hybrid ligand/receptor-based pharmacophore model for CXCR4 applied to a small-library of marine natural products led to the identification of Phidianidine A as a new CXCR4 ligand exhibiting antagonist activity 177
G PROTEIN ACTIVATION OF A HORMONE-STIMULATED PHOSPHATASE IN HUMAN TUMOR CELLS 177
Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231 177
Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment 177
Adult pituitary stem cells 176
Composti e metodi per rilevare lesioni aterosclerotiche precoci in vasi sanguigni 176
17{beta}-ESTRADIOL PROMOTES BREAST CANCER CELL PROLIFERATION INDUCING SDF-1-MEDIATED EGFR TRANSACTIVATION: REVERSAL BY GEFITINIB PRE-TREATMENT. 173
The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds 173
Pyrrolidinedithiocarbamate induces apoptosis in cerebellar granule cells: involvement of AP-1 and MAP kinases 173
Overexpression of stromal cell-derived factor 1 and its receptor CXCR4 induces autocrine/paracrine cell proliferation in human pituitary adenomas 173
Amyloid precursor protein and presenilin1 interact with the adaptor GRB2 and modulate ERK1,2 signaling 173
The phosphotyrosine phosphatase PTPh mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2 172
Stem-like signatures in human meningioma cells are under the control of CXCL11/CXCL12 chemokine activity 171
Differential role of EGF and bFGF in human GBM-TIC proliferation: relationship to EGFR-tyrosine kinase inhibitor sensitivity 171
Polydeoxyribonucleotides enhance the proliferation of human skin fibroblasts: involvement of A2, purinergic receptor subtypes 170
Chemokines and their receptors in the central nervous system 169
Expression of CXCR7 chemokine receptor in human meningioma cells and in intratumoral microvasculature 169
Addressing thermal and mechanical stability of human prion protein with single molecule and ensemble measurements 169
CXCR4 expression in feline mammary carcinoma cells: evidence of a proliferative role for the SDF-1/CXCR4 axis 168
Gefitinib targets EGFR dimerization and ERK1/2 phosphorylation to inhibit pleural mesothelioma cell proliferation 167
Totale 20.040
Salva come PNG Salva come JPEG
Categoria #
all - tutte 149.321
article - articoli 132.714
book - libri 0
conference - conferenze 8.049
curatela - curatele 0
other - altro 0
patent - brevetti 1.386
selected - selezionate 0
volume - volumi 7.172
Totale 298.642
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20223.663 152 379 195 400 110 262 269 813 147 281 172 483
2022/20233.127 308 199 36 308 436 553 7 246 547 42 384 61
2023/20241.980 121 213 51 237 139 386 149 122 114 58 120 270
2024/20256.841 200 458 216 531 942 681 637 1.219 262 280 613 802
2025/202612.134 1.390 368 1.383 1.080 1.316 947 1.648 590 935 1.191 598 688
2026/20271.277 1.277 0 0 0 0 0 0 0 0 0 0 0
Totale 46.977