IRIS
FLORIO, TULLIO
 Distribuzione geografica
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Continente #
EU - Europa 37.474
AS - Asia 3.693
NA - Nord America 1.878
SA - Sud America 357
AF - Africa 58
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 2
Totale 43.472
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Nazione #
IT - Italia 36.826
US - Stati Uniti d'America 1.784
SG - Singapore 1.627
CN - Cina 1.013
VN - Vietnam 638
FR - Francia 305
BR - Brasile 219
HK - Hong Kong 141
DE - Germania 79
FI - Finlandia 63
AR - Argentina 54
GB - Regno Unito 46
MX - Messico 45
JP - Giappone 36
CA - Canada 30
IN - India 30
IQ - Iraq 30
ID - Indonesia 26
CH - Svizzera 25
BD - Bangladesh 24
CO - Colombia 20
EC - Ecuador 20
IE - Irlanda 16
PK - Pakistan 15
PL - Polonia 15
ZA - Sudafrica 15
NL - Olanda 14
RU - Federazione Russa 14
PH - Filippine 13
UA - Ucraina 13
CL - Cile 12
KR - Corea 12
ES - Italia 11
TR - Turchia 11
KE - Kenya 10
VE - Venezuela 10
AU - Australia 8
MA - Marocco 8
TH - Thailandia 8
TW - Taiwan 7
UY - Uruguay 7
AT - Austria 6
KZ - Kazakistan 6
PE - Perù 6
BO - Bolivia 5
JO - Giordania 5
NP - Nepal 5
SA - Arabia Saudita 5
SE - Svezia 5
UZ - Uzbekistan 5
AZ - Azerbaigian 4
BE - Belgio 4
DK - Danimarca 4
DZ - Algeria 4
LT - Lituania 4
PY - Paraguay 4
RO - Romania 4
SY - Repubblica araba siriana 4
BH - Bahrain 3
CR - Costa Rica 3
EG - Egitto 3
KG - Kirghizistan 3
MY - Malesia 3
NI - Nicaragua 3
OM - Oman 3
RS - Serbia 3
TN - Tunisia 3
AE - Emirati Arabi Uniti 2
BY - Bielorussia 2
CY - Cipro 2
GR - Grecia 2
HR - Croazia 2
HU - Ungheria 2
IL - Israele 2
JM - Giamaica 2
LB - Libano 2
LV - Lettonia 2
NG - Nigeria 2
SI - Slovenia 2
SV - El Salvador 2
TT - Trinidad e Tobago 2
TZ - Tanzania 2
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
CI - Costa d'Avorio 1
CW - ???statistics.table.value.countryCode.CW??? 1
CZ - Repubblica Ceca 1
DO - Repubblica Dominicana 1
GA - Gabon 1
GP - Guadalupe 1
HN - Honduras 1
IR - Iran 1
KH - Cambogia 1
KW - Kuwait 1
LC - Santa Lucia 1
LK - Sri Lanka 1
LY - Libia 1
Totale 43.455
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Città #
Genova 20.899
Genoa 10.388
Vado Ligure 2.756
Rapallo 2.540
Singapore 760
San Jose 666
Lauterbourg 281
Ashburn 247
Ho Chi Minh City 197
Council Bluffs 164
Hong Kong 138
Beijing 137
Hanoi 137
New York 92
Bordighera 66
Santa Clara 66
Frankfurt am Main 62
Helsinki 58
Haiphong 38
Tokyo 33
Tianjin 32
St Louis 30
Mexico City 29
Los Angeles 26
São Paulo 25
Milan 24
Da Nang 22
Zurich 20
Chicago 19
Dublin 15
Hải Dương 13
Warsaw 13
Orem 12
Amsterdam 11
City of London 11
Rome 11
Biên Hòa 10
Ninh Bình 10
Rio de Janeiro 10
Shanghai 10
Baghdad 9
Montreal 9
Nairobi 9
Quito 9
Atlanta 8
Curitiba 8
Guangzhou 8
Jakarta 8
Thái Bình 8
Brasília 7
Madrid 7
Nha Trang 7
Belo Horizonte 6
Buenos Aires 6
Can Tho 6
Cardiff 6
Des Moines 6
London 6
Montevideo 6
Nuremberg 6
Poplar 6
Porto Alegre 6
Santiago 6
Amman 5
Bangkok 5
Buffalo 5
Chennai 5
Denver 5
Erbil 5
Johannesburg 5
Karachi 5
Lappeenranta 5
Mumbai 5
Padua 5
Paris 5
Quận Ba 5
Turin 5
Baku 4
Bogotá 4
Bắc Ninh 4
Cape Town 4
Casablanca 4
Charlotte 4
Dallas 4
Houston 4
Kyiv 4
Lima 4
Medellín 4
Naples 4
Nova Iguaçu 4
Quảng Ngãi 4
Sydney 4
Tashkent 4
Toronto 4
Vienna 4
Almaty 3
Ankara 3
Arlington 3
Azzano San Paolo 3
Bari 3
Totale 40.398
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Nome #
Biomimetic hybrid vesicles for boron neutron capture therapy of glioblastoma 259
Development of an Injectable Slow-Release Metformin Formulation and Evaluation of Its Potential Antitumor Effects 258
NDM29, a RNA polymerase III-dependent non coding RNA, promotes amyloidogenic processing of APP and amyloid β secretion 256
17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease 251
Characterization of the pro-apoptotic intracellular mechanisms induced by a toxic conformer of the recombinant human prion protein fragment 90-231 247
Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells 242
Amyloid precursor protein modulates ERK1/2 signaling 241
New molecules and old drugs as emerging approaches to selectively target human glioblastoma cancer stem cells 237
Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets. 235
The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma 233
Anti-proliferative and anti-secretory effects of everolimus on human pancreatic neuroendocrine tumors primary cultures: is there any benefit from combination with somatostatin analogs? 232
Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors 230
Calcium binding promotes Prion Protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure 230
Amyloid precursor protein and Presenilin 1 interaction studied by FRET in human H4 cells. 224
Human glioblastoma-derived cell membrane nanovesicles: a novel, cell-specific strategy for boron neutron capture therapy of brain tumors 221
The inhibition of 45A ncRNA expression reduces tumor formation, affecting tumor nodules compactness and metastatic potential in neuroblastoma cells 221
Peptide Receptor Targeting in Cancer: The Somatostatin Paradigm 220
A critical concentration of N-terminal pyroglutamylated amyloid beta drives the misfolding of Ab1-42 into more toxic aggregates 219
In vitro and in vivo characterization of stem-like cells from canine osteosarcoma and assessment of drug sensitivity 218
Apoptotic cell death and impairment of L-type voltage sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126 215
Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis 214
Dual modulation of ERK1/2 and p38 MAP kinase activities induced by minocycline reverses the neurotoxic effects of the prion protein fragment 90-231 209
Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells 209
Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity. 209
Protective effects of some creatine derivatives in brain tissue anoxia. 208
Amino-terminally truncated prion protein PrP90-231 induces microglial activation in vitro 204
An Alu-like RNA promotes cell differentiation and reduces malignancy of human neuroblastoma cells. 203
In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors 200
Adiponectin as Novel Regulator of Cell Proliferation in Human Glioblastoma 199
A Novel Collection of snRNA-Like Promoters with Tissue-Specific Transcription Properties 198
Chemokines and chemokine receptors: New actors in neuroendocrine regulations 197
Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells 197
Complexity and Selectivity of γ-Secretase Cleavage on Multiple Substrates: Consequences in Alzheimer's Disease and Cancer 196
Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death 196
Differential toxicity, conformation and morphology of typical initial aggregation states of Aβ1-42 and Aβpy3-42 beta-amyloids 195
Autophagy Activator Drugs: A New Opportunity in Neuroprotection from Misfolded Protein Toxicity 195
Amyloid precursor protein and presenilin involvement in cell signaling 194
A novel snRNA-like transcript affects amyloidogenesis and cell cycle progression through perturbation of Fe65L1 (APBB2) alternative splicing. 194
Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current 193
Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90–231 Neurotoxic Effects in Cerebellar Granule Neurons 193
Inhibition of chloride intracellular channel 1 (CLIC1) as biguanide class-effect to impair human glioblastoma stem cell viability 192
Co-Administration of Fendiline Hydrochloride Enhances Chemotherapeutic Efficacy of Cisplatin in Neuroblastoma Treatment 191
Endometrial stem cells and human reproductive failure 190
SDF1 controls pituitary cell proliferation through the activation of ERK1/2 and the Ca2+-dependent cytosolic tyrosine kinase, Pyk2. 190
Down-regulation of 21A Alu RNA as a tool to boost proliferation maintaining the tissue regeneration potential of progenitor cells 189
An interaction between hepatocyte growth factor and its receptor (c-MET) prolongs the survival of chronic lymphocytic leukemic cells through STAT3 phosphorylation: a potential role of mesenchymal cells in the disease 188
Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA 188
Phenotypical and Pharmacological Characterization of Stem-Like Cells in Human Pituitary Adenomas 187
Perhexiline maleate enhances antitumor efficacy of cisplatin in neuroblastoma by inducing over-expression of NDM29 ncRNA 187
Proteostasis unbalance in prion diseases: mechanisms of neurodegeneration and therapeutic targets 185
The somatostatin analogue octreotide confers sensitivity to rapamycin treatment on pituitary tumor cells 184
Glioblastoma cancer stem cells: response to epidermal growth factor receptor kinase inhibitors 184
Drug design strategies focusing on the CXCR4/CXCR7/CXCL12 pathway in leukemia and lymphoma 184
Drug-repositioning opportunities for cancer therapy: Novel molecular targets for known compounds 184
Receptor tyrosine kinase inhibitors and cytotoxic drugs affect pleural mesothelioma cell proliferation: insight into EGFR and ERK1/2 as antitumor targets 183
Differential efficacy of SSTR1, 2 and 5 agonists in the inhibition of C6 glioma growth in nude mice 181
Different structural stability and toxicity of PrPARR and PrPARQ sheep prion protein variants 180
Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic 180
Canine osteosarcoma cell lines contain stem-like cancer cells: Biological and pharmacological characterization 180
Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives 180
b25-35 alters calcium homeostasis and induces neurotoxicity in cerebellar granule cells 179
Balance between somatostatin and D2 receptor expression drives TSH-secreting adenoma response to somatostatin analogs and dopastatins 179
Emerging targets in pituitary adenomas: role of the CXCL12/CXCR4-R7 system 178
Novel celecoxib analogues inhibit glial production of prostaglandinE2, nitric oxide, and oxygen radicals reverting the neuroinflammatoryresponses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide 178
Chemokines and their receptors in the CNS: expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation 177
Different response of human glioma tumor-initiating cells to EGFR kinase inhibitors. 176
Effects of Prion Protein on Aβ42 and Pyroglutamate-Modified AβpΕ3-42 Oligomerization and Toxicity 176
Biological and Biochemical Basis of the Differential Efficacy of First and Second Generation Somatostatin Receptor Ligands in Neuroendocrine Neoplasms 175
SOMATOSTATIN ACTIVATION OF MITOGEN ACTIVATED PROTEIN KINASE VIA SOMATOSTATIN RECEPTOR 1 (SSTR1) 174
Adult pituitary stem cells 174
A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis 174
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction 173
Neuroblastoma: Inhibition by Alu-Like RNA 173
Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures 173
ACTIVATION OF AUTOPHAGY PATHWAY AS NEUROPROTECTIVE MECHANISM AGAINST AMYLOIDOGENIC PRION PEPTIDE 172
The chemokine SDF1/CXCL12: a novel autocrine/paracrine factor involved in pituitary adenoma development 171
Minimalist hybrid ligand/receptor-based pharmacophore model for CXCR4 applied to a small-library of marine natural products led to the identification of Phidianidine A as a new CXCR4 ligand exhibiting antagonist activity 171
Molecular pharmacology of malignant pleural mesothelioma: Challenges and perspectives from preclinical and clinical studies 171
Chemokine stromal cell-derived factor 1α induces proliferation and growth hormone release in GH4C1 rat pituitary adenoma cell line through multiple intracellular signals 170
G PROTEIN ACTIVATION OF A HORMONE-STIMULATED PHOSPHATASE IN HUMAN TUMOR CELLS 170
Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment 170
The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds 169
Composti e metodi per rilevare lesioni aterosclerotiche precoci in vasi sanguigni 169
Patient-derived xenograft in zebrafish embryos: a new platform for translational research in neuroendocrine tumors 168
Pyrrolidinedithiocarbamate induces apoptosis in cerebellar granule cells: involvement of AP-1 and MAP kinases 168
Polydeoxyribonucleotides enhance the proliferation of human skin fibroblasts: involvement of A2, purinergic receptor subtypes 168
Differential role of EGF and bFGF in human GBM-TIC proliferation: relationship to EGFR-tyrosine kinase inhibitor sensitivity 167
Chemokines and their receptors in the central nervous system 167
Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231 166
ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation 165
A. novel mechanism for the melatonin inhibition of testosterone secretion by rat Leydig cells: reduction of GnRH-induced cytosolic Ca2+ rise 165
17{beta}-ESTRADIOL PROMOTES BREAST CANCER CELL PROLIFERATION INDUCING SDF-1-MEDIATED EGFR TRANSACTIVATION: REVERSAL BY GEFITINIB PRE-TREATMENT. 164
Amyloid precursor protein and presenilin1 interact with the adaptor GRB2 and modulate ERK1,2 signaling 163
Gefitinib targets EGFR dimerization and ERK1/2 phosphorylation to inhibit pleural mesothelioma cell proliferation 160
Chronic lymphocytic leukemic (CLL) B cells express the HGF receptor (C-MET) and are supported in their survival by HGF-producing mesenchymal stromal cell 160
Expression of CXCR7 chemokine receptor in human meningioma cells and in intratumoral microvasculature 160
Steroid modulation of prolactin release from single lactotropes in male and female rats studied by the reverse hemolytic plaque assay 160
The phosphotyrosine phosphatase PTPh mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2 159
Overexpression of stromal cell-derived factor 1 and its receptor CXCR4 induces autocrine/paracrine cell proliferation in human pituitary adenomas 159
Cultured astrocyte proliferation induced by extracellular guanosine involves endogenous adenosine and is raised by the co-presence of microglia 159
Totale 19.169
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Categoria #
all - tutte 135.333
article - articoli 120.421
book - libri 0
conference - conferenze 7.121
curatela - curatele 0
other - altro 0
patent - brevetti 1.280
selected - selezionate 0
volume - volumi 6.511
Totale 270.666
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021630 0 0 0 0 0 0 0 0 0 302 179 149
2021/20223.663 152 379 195 400 110 262 269 813 147 281 172 483
2022/20233.127 308 199 36 308 436 553 7 246 547 42 384 61
2023/20241.980 121 213 51 237 139 386 149 122 114 58 120 270
2024/20256.841 200 458 216 531 942 681 637 1.219 262 280 613 802
2025/202610.779 1.390 368 1.383 1.080 1.316 947 1.648 590 935 1.122 0 0
Totale 44.345