IRIS
CEA, MICHELE
 Distribuzione geografica
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Continente #
EU - Europa 14.489
AS - Asia 1.855
NA - Nord America 1.279
SA - Sud America 157
AF - Africa 31
OC - Oceania 3
Totale 17.814
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Nazione #
IT - Italia 14.134
US - Stati Uniti d'America 1.199
SG - Singapore 695
CN - Cina 466
VN - Vietnam 364
BD - Bangladesh 152
FR - Francia 119
BR - Brasile 92
HK - Hong Kong 68
DE - Germania 50
FI - Finlandia 45
AR - Argentina 37
CA - Canada 35
GB - Regno Unito 33
MX - Messico 24
IN - India 20
JP - Giappone 20
IQ - Iraq 17
CH - Svizzera 13
ID - Indonesia 13
NL - Olanda 13
ES - Italia 10
UA - Ucraina 10
SE - Svezia 8
AT - Austria 7
EC - Ecuador 7
IE - Irlanda 7
CO - Colombia 6
MA - Marocco 6
PY - Paraguay 6
RU - Federazione Russa 6
GR - Grecia 5
PK - Pakistan 5
ZA - Sudafrica 5
BE - Belgio 4
HR - Croazia 4
JM - Giamaica 4
PH - Filippine 4
SA - Arabia Saudita 4
TH - Thailandia 4
TR - Turchia 4
VE - Venezuela 4
AU - Australia 3
DZ - Algeria 3
EG - Egitto 3
KE - Kenya 3
KR - Corea 3
LT - Lituania 3
TN - Tunisia 3
UY - Uruguay 3
UZ - Uzbekistan 3
BB - Barbados 2
BH - Bahrain 2
CL - Cile 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GT - Guatemala 2
HN - Honduras 2
HU - Ungheria 2
LB - Libano 2
PA - Panama 2
PL - Polonia 2
RO - Romania 2
RS - Serbia 2
SI - Slovenia 2
SY - Repubblica araba siriana 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
AO - Angola 1
BG - Bulgaria 1
BY - Bielorussia 1
BZ - Belize 1
CR - Costa Rica 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
GA - Gabon 1
GP - Guadalupe 1
HT - Haiti 1
JO - Giordania 1
KG - Kirghizistan 1
KH - Cambogia 1
KZ - Kazakistan 1
MD - Moldavia 1
MG - Madagascar 1
MT - Malta 1
NG - Nigeria 1
NI - Nicaragua 1
NP - Nepal 1
OM - Oman 1
PT - Portogallo 1
SN - Senegal 1
SV - El Salvador 1
TT - Trinidad e Tobago 1
TZ - Tanzania 1
Totale 17.814
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Città #
Genova 6.805
Genoa 4.974
Rapallo 1.092
Vado Ligure 1.015
San Jose 328
Singapore 327
Ashburn 211
Ho Chi Minh City 114
Lauterbourg 107
Beijing 102
Hanoi 85
Hong Kong 67
Council Bluffs 66
New York 52
Frankfurt am Main 43
Helsinki 39
Los Angeles 33
Santa Clara 33
Milan 22
Bordighera 21
Tokyo 19
Chicago 17
Haiphong 17
Rome 17
Boardman 16
Orem 15
Phoenix 15
Buffalo 14
Da Nang 14
Turin 14
Mexico City 13
Tianjin 13
São Paulo 12
Zurich 12
Amsterdam 10
Dallas 10
Can Tho 9
Cardiff 9
Columbus 9
Schiavon 9
Baghdad 8
Biên Hòa 8
Montreal 8
Naples 8
Brooklyn 7
City of London 7
Dublin 7
Phủ Lý 7
Buenos Aires 6
Denver 6
Hải Dương 6
Lappeenranta 6
London 6
Palermo 6
Bologna 5
Florence 5
Kyiv 5
Madrid 5
Nha Trang 5
Paris 5
Poplar 5
Stockholm 5
Washington 5
Bắc Ninh 4
Changsha 4
Dhaka 4
Ficarolo 4
Houston 4
Miami 4
Toronto 4
Zagreb 4
Antwerp 3
Belo Horizonte 3
Brasília 3
Brescia 3
Charlotte 3
Cuenca 3
Djursholm 3
Guangzhou 3
Istanbul 3
Johannesburg 3
Kingston 3
Las Vegas 3
Louisville 3
Manchester 3
Montevideo 3
Montoro 3
Mumbai 3
Nairobi 3
Ninh Bình 3
Parma 3
Perugia 3
Piscataway 3
Pittsburgh 3
Queens 3
Rio de Janeiro 3
Tashkent 3
Thái Bình 3
Vancouver 3
Addis Ababa 2
Totale 16.059
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Nome #
APO866 increases antitumor activity of cyclosporin - A by inducing mitochondrial and endoplasmic reticulum stress in leukemia cells 318
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of AKT-mediated gene repression 249
APO866 activity in hematologic malignancies: a preclinical in vitro study. 247
APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment 244
Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells vulnerability to DNA-damaging agents 244
Autophagy in blood cancers: biological role and therapeutic implications. 238
Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors and DNA repair. 236
Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin. 228
A simple cytofluorimetric score may optimize testing for biallelic CEBPA mutations in patients with acute myeloid leukemia 221
Catastrophic NAD(+) Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE 219
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells 214
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. 205
Dexamethasone, oxaliplatin and cytarabine (R-DHAOx) as salvage and stem cells mobilizing therapy in relapsed/refractory diffuse large B cell lymphomas 205
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects 202
Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells 201
Ras-induced resistance to lapatinib is overcome by MEK inhibition 200
Sirt6 regulates dendritic cell differentiation, maturation, and function 196
Molecular diagnosis and monitoring of chronic myelogenous leukemia: BCR-Abl and more. 193
Fasting potentiates the anticancer activity of tyrosin kinase inhibitors by strenghtening MAPK signalling inhibition. 191
Monoclonal antibodies for non-Hodgkin's lymphoma: state of the art and perspectives. 189
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 188
Treatment with KLEPTOSE® CRYSMEB reduces mouse atherogenesis by impacting on lipid profile and Th1 lymphocyte response 183
Early minimal residual disease assessment after AML induction with fludarabine, cytarabine and idarubicin (FLAI) provides the most useful prognostic information 182
Peripheral blood vs. bone marrow for molecular monitoring of BCR-ABL1 levels in chronic myelogenous leukemia, a retrospective analysis in allogeneic bone marrow recipients. 182
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition 182
Evaluating treatment response of chronic myeloid leukemia: emerging science and technology. 178
Hedgehog Signaling Is Useful as a Novel Molecular Marker for Predicting Relapse and Resistance During Chronic Myeloid Leukemia Treatment 177
Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors As Therapeutics: Rationales, Controversies, Clinical Experience. 177
Post-Transplant Nivolumab Plus Unselected Autologous Lymphocytes in Refractory Hodgkin Lymphoma: A Feasible and Promising Salvage Therapy Associated With Expansion and Maturation of NK Cells 177
Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols. 176
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 174
Intraplaque Expression of C-Reactive Protein Predicts Cardiovascular Events in Patients with Severe Atherosclerotic Carotid Artery Stenosis 174
CD38-Induced Metabolic Dysfunction Primes Multiple Myeloma Cells for NAD+-Lowering Agents 172
The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival 172
Evaluation of prognostic indices in elderly hospitalized patients 172
The new small tyrosine-kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs 172
Prognostic relevance of a blastic plasmacytoid dendritic cell neoplasm-like immunophenotype in cytogenetically normal acute myeloid leukemia patients 168
NAD+ METABOLISM RESTRICTION BOOSTS HIGH-DOSE MELPHALAN EFFICACY IN PATIENTS WITH MULTIPLE MYELOMA 167
Longitudinal minimal residual disease (MRD) evaluation in acute myeloid leukaemia with NPM1 mutation: from definition of molecular relapse to MRD-driven salvage approach 167
Nicotinamide Phosphoribosyltransferase As A Target In Inflammation-Related Disorders. 166
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal-transition-like transcriptional activation 166
Abstract CT075: Fasting-mimicking diet and hormone therapy modulates metabolic factors to promote breast cancer regression and reduce side effects 166
Biological Insights into Myeloma and Other B Cell Malignancies 165
Dual NAMPT and BTK targeting leads to synergistic killing of Waldenström macroglobulinemia cells regardless of MYD88 and CXCR4 somatic mutation status 162
Predictive values of two frailty screening tools in older patients with solid cancer: a comparison of SAOP2 and G8 162
Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status 161
Exploiting tumor vulnerabilities: NAD+-depleting agents combined with anti-tumor drugs as innovative strategy to treat hematological malignancies 161
Catastrophic NAD+ Depletion through Nampt Inhibition in Activated T Lymphocytes Reduces Demyelination and Disability in EAE. 159
Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives 155
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 155
Radiomics and artificial intelligence analysis of CT data for the identification of prognostic features in multiple myeloma 155
Differentiating diffuse from focal pattern on Computed Tomography in multiple myeloma: Added value of a Radiomics approach 154
Synthesis of Pyrrolidine 3,4-Diol Derivatives with Anticancer Activity on Pancreatic Tumor Cells 153
Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma 152
Amino acid depletion triggered by L-asparaginase sensitizes MM cells to carfilzomib by inducing mitochondria ROS-mediated cell death 152
HDAC INHIBITORS SYNERGISTICALLY ENHANCE AP0866 ACTIVITY IN HUMAN LEUKEMIA CELLS: EVIDENCE FOR CONVERGING MECHANISMS OF SIRT1 INHIBITION 151
Targeting NAD(+) Salvage Pathway Induces Autophagy in Multiple Myeloma Cells 150
New insights into biology of chronic myeloid leukemia: implications in therapy. 150
A T315I mutation in e19a2 BCR/ABL1 chronic myeloid leukemia responding to dasatinib 150
CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: Molecular mechanisms and therapeutic implications 149
Novel 2-[(benzylamino)methyl]pyrrolidine-3,4-diol derivatives as alpha-mannosidase inhibitors and with antitumor activities against hematological and solid malignancies. 148
Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma 146
Targeting NAD+ Salvage Pathway Induces Autophagy in Multiple Myeloma Cells via mTORC1 and Extracellular Signal-Regulated Kinase (ERK1/2) Inhibition 145
Fludarabine, high-dose cytarabine and idarubicin-based induction may overcome the negative prognostic impact of flt3-itd in npm1 mutated aml, irrespectively of flt3-itd allelic Burden 145
Post-Transplant Nivolumab Plus Unselected Autologous Lymphocytes in Refractory Hodgkin Lymphoma: A Feasible and Promising Salvage Therapy Associated With Expansion and Maturation of NK Cells 144
Safety and feasibility of fasting‐mimicking diet and effects on nutritional status and circulating metabolic and inflammatory factors in cancer patients undergoing active treatment 144
Radiomics and artificial intelligence for outcome prediction in multiple myeloma patients undergoing autologous transplantation: A feasibility study with ct data 143
New insights into the treatment of multiple myeloma with histone deacetylase inhibitors. 142
Intracellular NAD⁺ depletion enhances bortezomib-induced anti-myeloma activity. 141
Nutrients in the Prevention of Alzheimer's Disease 141
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses. 139
Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma 138
SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice 137
Subcutaneous bortezomib-containing regimens as up-front treatment of newly diagnosed transplant-eligible multiple myeloma patients: a retrospective, non-interventional observational study 137
Apoptosis reprogramming triggered by splicing inhibitors sensitizes multiple myeloma cells to Venetoclax treatment 131
Harnessing Immune Response in Acute Myeloid Leukemia 126
Targeting Inflammation in Primary Cardiovascular Prevention 126
Effect of Geriatric Comanagement in Older Patients Undergoing Surgery for Gastrointestinal Cancer: A Retrospective, Before-and-After Study 125
SIRT6 inhibition as a novel approach for treating Acute Myeloid Leukemia 125
Depletion of the intracellular coenzyme NAD plus in activated T-cells ameliorates experimental autoimmune encephalomyelitis 125
Cyclic fasting bolsters cholesterol biosynthesis inhibitors' anticancer activity 124
Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity. 123
Intracellular NAD+ depletion induces autophagic-death in Multiple Myeloma cells 123
Novel anti-B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma 122
Current standards and future strategies in immunochemotherapy of non-Hodgkin's lymphoma. 116
A Blastic Plasmacytoid Dendritic Cell Neoplasm-like Phenotype Identifies a Subgroup of NPM1-Mutated AML Patients with Worse Prognosis While Has Not Predictive Value in NPM1-Wt AML 115
Potent Synergistic Activity of the NAD plus Synthesis Inhibitor APO866 and of the Apoptosis Inducer TRAIL in in Vitro and Ex Vivo Cellular Models of Non Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia. 114
Daratumumab in the treatment of C3 glomerulopathy with monoclonal gammopathy: a case report and literature review 110
Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells 110
Synergistic Interaction Between P-glycoprotein Inhibitors and APO866 in Primary Leukemic Cells 105
Author Correction: Cyclic fasting bolsters cholesterol biosynthesis inhibitors' anticancer activity 104
Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies 103
The Novel Phosphatidylinositol-3-Kinase (PI3K) Inhibitor Alpelisib Effectively Inhibits Growth of PTEN-Haploinsufficient Lipoma Cells 103
Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery 103
CD56 expression modulates NAD+ metabolic landscape and predicts sensitivity to anti-CD38 therapies in multiple myeloma 101
Calciphylaxis in a patient with POEMS syndrome without renal failure and/or hyperparathyroidism. A case report 99
Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model 99
Myeloma Spine and Bone Damage Score (MSBDS) on Whole-Body Computed Tomography (WBCT): Multiple Reader Agreement in a Multicenter Reliability Study 98
Pre-transplant minimal residual disease assessment and transplant-related factors predict the outcome of acute myeloid leukemia patients undergoing allogeneic stem cell transplantation 96
Monoclonal gammopathy of renal significance (MGRS): retrospective monocentric analysis of clinical outcomes and treatment strategies 94
Totale 15.984
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Categoria #
all - tutte 58.719
article - articoli 57.119
book - libri 0
conference - conferenze 1.600
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 117.438
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202169 0 0 0 0 0 0 0 0 0 0 0 69
2021/20221.250 43 63 100 156 63 102 69 247 72 110 63 162
2022/20231.379 145 153 17 142 228 177 9 82 200 28 175 23
2023/20241.006 36 92 33 144 96 182 79 96 31 21 72 124
2024/20252.977 124 186 63 236 288 289 276 563 89 176 328 359
2025/20265.770 670 227 599 520 707 371 747 277 409 613 416 214
Totale 18.197