IRIS
CORSARO, ALESSANDRO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 10.626
AS - Asia 1.106
NA - Nord America 1.075
Continente sconosciuto - Info sul continente non disponibili 195
SA - Sud America 118
AF - Africa 22
OC - Oceania 4
Totale 13.146
Salva come PNG Salva come JPEG
Nazione #
IT - Italia 10.456
US - Stati Uniti d'America 1.013
SG - Singapore 440
CN - Cina 271
VN - Vietnam 194
BD - Bangladesh 82
FR - Francia 75
BR - Brasile 69
HK - Hong Kong 39
DE - Germania 26
CA - Canada 20
AR - Argentina 17
GB - Regno Unito 15
ID - Indonesia 14
MX - Messico 13
JP - Giappone 12
CO - Colombia 11
IQ - Iraq 11
FI - Finlandia 10
IN - India 9
EC - Ecuador 8
JM - Giamaica 7
ZA - Sudafrica 7
CH - Svizzera 6
CL - Cile 5
JO - Giordania 5
NL - Olanda 5
PR - Porto Rico 5
HN - Honduras 4
PH - Filippine 4
PK - Pakistan 4
TH - Thailandia 4
AU - Australia 3
BO - Bolivia 3
CR - Costa Rica 3
DK - Danimarca 3
ES - Italia 3
RO - Romania 3
TR - Turchia 3
UA - Ucraina 3
VE - Venezuela 3
AT - Austria 2
BE - Belgio 2
BH - Bahrain 2
CY - Cipro 2
GT - Guatemala 2
IE - Irlanda 2
KE - Kenya 2
KZ - Kazakistan 2
LV - Lettonia 2
MY - Malesia 2
PL - Polonia 2
PT - Portogallo 2
RU - Federazione Russa 2
SC - Seychelles 2
TN - Tunisia 2
TT - Trinidad e Tobago 2
TZ - Tanzania 2
BG - Bulgaria 1
BS - Bahamas 1
BY - Bielorussia 1
BZ - Belize 1
DZ - Algeria 1
GA - Gabon 1
GP - Guadalupe 1
HR - Croazia 1
KR - Corea 1
KY - Cayman, isole 1
LK - Sri Lanka 1
LT - Lituania 1
LY - Libia 1
MA - Marocco 1
NC - Nuova Caledonia 1
NG - Nigeria 1
NO - Norvegia 1
NP - Nepal 1
OM - Oman 1
PA - Panama 1
PY - Paraguay 1
RS - Serbia 1
SA - Arabia Saudita 1
SI - Slovenia 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TG - Togo 1
UG - Uganda 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 12.952
Salva come PNG Salva come JPEG
Città #
Genova 5.616
Genoa 3.006
Vado Ligure 868
Rapallo 833
San Jose 242
Singapore 215
Ashburn 154
Lauterbourg 72
Ho Chi Minh City 55
Beijing 48
New York 40
Hanoi 37
Hong Kong 37
Santa Clara 30
Council Bluffs 29
Bordighera 26
Frankfurt am Main 22
Los Angeles 18
Chicago 16
Milan 15
Rome 12
St Louis 11
Tokyo 10
Da Nang 9
Haiphong 9
Tianjin 9
Brooklyn 8
Helsinki 7
São Paulo 7
Jakarta 6
Mexico City 6
Zurich 6
Bologna 5
Dallas 5
Miami 5
Phoenix 5
Rio de Janeiro 5
Amman 4
Atlanta 4
Buffalo 4
City of London 4
Hải Dương 4
Johannesburg 4
London 4
Louisville 4
Medellín 4
Montreal 4
Nashville 4
Nha Trang 4
Pittsburgh 4
Quito 4
Santiago 4
Thái Bình 4
Verona 4
Acalanes Ridge 3
Alpharetta 3
Amsterdam 3
Baghdad 3
Bangkok 3
Bari 3
Biên Hòa 3
Boardman 3
Cardiff 3
Charlotte 3
Curitiba 3
Erbil 3
Florence 3
Lappeenranta 3
Ninh Bình 3
Parma 3
Philadelphia 3
Plano 3
Princeton 3
Queens 3
San Antonio 3
San José 3
Savannah 3
Shanghai 3
Suzhou 3
Tampa 3
Toms River 3
Toronto 3
Virginia Beach 3
Warsaw 3
Anna 2
Antioch 2
Azusa 2
Belo Horizonte 2
Berazategui 2
Birmingham 2
Boston 2
Brasília 2
Brussels 2
Bắc Ninh 2
Camden 2
Can Tho 2
Cheyenne 2
Clanton 2
Clearwater 2
Columbus 2
Totale 11.694
Salva come PNG Salva come JPEG
Nome #
Characterization of the pro-apoptotic intracellular mechanisms induced by a toxic conformer of the recombinant human prion protein fragment 90-231 265
Amyloid precursor protein modulates ERK1/2 signaling 259
Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells 257
Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors 241
Calcium binding promotes Prion Protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure 238
Amyloid precursor protein and Presenilin 1 interaction studied by FRET in human H4 cells. 231
Human glioblastoma-derived cell membrane nanovesicles: a novel, cell-specific strategy for boron neutron capture therapy of brain tumors 227
A critical concentration of N-terminal pyroglutamylated amyloid beta drives the misfolding of Ab1-42 into more toxic aggregates 227
Peptide Receptor Targeting in Cancer: The Somatostatin Paradigm 226
In vitro and in vivo characterization of stem-like cells from canine osteosarcoma and assessment of drug sensitivity 225
Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis 224
Amino-terminally truncated prion protein PrP90-231 induces microglial activation in vitro 223
Apoptotic cell death and impairment of L-type voltage sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126 222
Dual modulation of ERK1/2 and p38 MAP kinase activities induced by minocycline reverses the neurotoxic effects of the prion protein fragment 90-231 217
SDF1 controls pituitary cell proliferation through the activation of ERK1/2 and the Ca2+-dependent cytosolic tyrosine kinase, Pyk2. 212
Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells 205
Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death 205
Autophagy Activator Drugs: A New Opportunity in Neuroprotection from Misfolded Protein Toxicity 204
Differential toxicity, conformation and morphology of typical initial aggregation states of Aβ1-42 and Aβpy3-42 beta-amyloids 202
Amyloid precursor protein and presenilin involvement in cell signaling 201
Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90–231 Neurotoxic Effects in Cerebellar Granule Neurons 199
Proteostasis unbalance in prion diseases: mechanisms of neurodegeneration and therapeutic targets 198
Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic 195
Different structural stability and toxicity of PrPARR and PrPARQ sheep prion protein variants 194
Canine osteosarcoma cell lines contain stem-like cancer cells: Biological and pharmacological characterization 186
Emerging targets in pituitary adenomas: role of the CXCL12/CXCR4-R7 system 185
Effects of Prion Protein on Aβ42 and Pyroglutamate-Modified AβpΕ3-42 Oligomerization and Toxicity 184
ACTIVATION OF AUTOPHAGY PATHWAY AS NEUROPROTECTIVE MECHANISM AGAINST AMYLOIDOGENIC PRION PEPTIDE 184
ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation 182
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction 180
Chemokine stromal cell-derived factor 1α induces proliferation and growth hormone release in GH4C1 rat pituitary adenoma cell line through multiple intracellular signals 179
The chemokine SDF1/CXCL12: a novel autocrine/paracrine factor involved in pituitary adenoma development 177
Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231 177
Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment 177
The phosphotyrosine phosphatase PTPh mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2 172
Addressing thermal and mechanical stability of human prion protein with single molecule and ensemble measurements 169
Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation 164
Celecoxib, a COX-2 inhibitor, blocks microglial activation induced by a neurotoxic conformer of hPrP90-231 163
Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity 162
Aminoterminally truncated human Prion protein fragment 90-231 forms intracellular aggregates and causes lysosomal loss of impermeability 160
p38 MAP Kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells 157
Antitumor Potential of Antiepileptic Drugs in Human Glioblastoma: Pharmacological Targets and Clinical Benefits 156
Role of prion protein aggregation in neurotoxicity 156
Expression in E. coli and purification of recombinant fragments of wild type and mutant human prion protein 156
Emerging Role of Cellular Prion Protein in the Maintenance and Expansion of Glioma Stem Cells 152
High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein 151
Somatostatin receptor 1 (SSTR1)-mediated inhibition of cell proliferation correlates with the activation of the MAP kinase cascade: role of the phosphotyrosine phosphatase SHP-2 149
Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity 149
Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt 144
The expression of the phosphotyrosine phosphatase DEP-1/PTPeta dictates the responsivity of glioma cells to somatostatin inhibition of cell proliferation 141
Experimental Evidence and Clinical Implications of Pituitary Adenoma Stem Cells 141
Cabergoline modulation of alpha-subunits and FSH secretion in a gonadotroph adenoma 139
Molecular mechanisms involved in the aggregation and fibril formation of the recombinant human prion fragment PrP90-231 136
Identification of a conserved N-capping box important for the structural autonomy of the prion alpha 3-helix: the disease associated D202N mutation destabilizes the helical conformation 131
INTRACELLULAR MECHANISMS MEDIATING THE NEURONAL CELL DEATH AND ASTROGLIOSIS INDUCED BY THE PRION PROTEIN FRAGMENT 106-126 130
Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor 3 (SSTR3) mediated regulation of endothelial NOS and MAP kinase activities” 127
Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling 127
Intracellular accumulation of a mild-denatured monomer of the human PrP fragment 90-231 (hPrP90-231), as possible mechanism of its neurotoxic effects 126
Prion protein fragment 90-231 induces microglia activation: role of ERK1/2 and p38 MAP kinases in nitric oxide production and CCL5 secretion 126
In vitro and in vivo expression of somatostatin receptors in intermediate and malignant soft tissue tumors 125
Nitric oxide production stimulated by the basic fibroblast growth factor requires the synthesis of ceramide 124
Study of the Molecular Mechanism Responsible of the Conformational Changes Induced by E200K and D202N Pathological PrP Mutation 118
Expression of somatostatin receptors mRNA in human meningiomas and their implication in in vitro antiproliferative activity 118
Molecular mechanisms mediating the neuroprotective effects of quinacrine and minocycline on cell death induced by the prion protein fragment 90-231 (hPrP90-231) 114
The activation of the phosphotyrosine phosphatase h (r-PTPh) is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation 113
Study of the molecular mechanisms responsible of the transition of the prion protein fragment 90-231 in a neurotoxic conformation. 113
Somatostatin controls Kaposi sarcoma growth through inhibition of angiogenesis 110
Prolonged treatment with alpha-glycerylphosphorylethanolamine facilitates the acquisition of an active avoidance behavior and selectively increases neuronal signal transduction in rats 109
In vitro effect of human recombinant leptin and expression of leptin receptors on growth hormone-secreting human pituitary adenomas 108
Somatostatinergic control of Kaposi’s sarcoma growth through the inhibition of angiogenesis 103
The expression of pro-prion, a transmembrane isoform of the prion protein, leads to the constitutive activation of the canonical Wnt/β-catenin pathway to sustain the stem-like phenotype of human glioblastoma cells 102
Neurotoxicity of the recombinant prion protein fragment 90-231 in SH-SY5Y cells is dependent on its conversion in beta-structured-isoform 95
N6-isopentenyladenosine hinders the vasculogenic mimicry in human glioblastoma cells through Src-120 catenin pathway modulation and RhoA activity inhibition 95
Characterization of the intracellular mechanisms mediating somatostatin and lanreotide inhibition of DNA synthesis and growth hormone release from dispersed human GH-secreting pituitary adenoma cells in vitro 93
Somatostatin and its analog lanreotide inhibit the proliferation of dispersed human non-functioning pituitary adenoma cells in vitro 93
Somatostatin receptor subtype-dependent regulation of NO release: involvement of different intracellular pathways 85
New therapeutic strategies for Alzheimer’s disease by determination of structure and toxicity of oligomeric beta-amyloids aggregation states 79
Simple and Rapid Model to Generate Differentiated Endometrial Floating Organoids 77
A floating endometrial organoid model recapitulates epithelial-stromal cell interactions in vitro 77
The interaction of humic substances with the human prion protein fragment 90-231 affects its protease K resistance and cell internalization 77
The activation of the phosphotyrosine phosphatase eta is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation 70
Chemokine signaling in tumors: potential role of CXC chemokines and their receptors as glioblastoma therapeutic targets 69
Drug enteric metabolism in gut microbiota-brain crosstalk 34
The PDE5 inhibitor vardenafil enhances glutamatergic transmission through amyloid-beta and cellular prion protein 19
Intracellular accumulation of a mild-denatured monomer of the human PrP fragment 90-231, as possible mechanism of its neurotoxic effects 18
Microglia Reprogramming in Glioblastoma: Stem Cell-Derived Factors as Emerging Immunomodulators 16
Totale 13.146
Salva come PNG Salva come JPEG
Categoria #
all - tutte 39.663
article - articoli 37.636
book - libri 0
conference - conferenze 1.650
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 377
Totale 79.326
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022978 28 102 56 99 36 71 76 230 31 77 44 128
2022/2023975 70 56 11 91 163 169 3 95 148 5 152 12
2023/2024553 27 55 10 84 40 149 39 30 23 13 32 51
2024/20252.061 55 114 59 197 282 231 188 374 74 70 192 225
2025/20263.398 396 79 487 284 383 244 441 163 231 335 183 172
2026/2027380 380 0 0 0 0 0 0 0 0 0 0 0
Totale 13.146