IRIS
BRUZZONE, SANTINA
 Distribuzione geografica
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Continente #
EU - Europa 28.752
AS - Asia 3.465
NA - Nord America 1.708
SA - Sud America 312
AF - Africa 68
OC - Oceania 5
Totale 34.310
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Nazione #
IT - Italia 28.131
US - Stati Uniti d'America 1.616
SG - Singapore 1.440
CN - Cina 893
VN - Vietnam 728
FR - Francia 233
BR - Brasile 179
HK - Hong Kong 144
DE - Germania 92
FI - Finlandia 73
GB - Regno Unito 63
AR - Argentina 55
JP - Giappone 53
MX - Messico 52
BD - Bangladesh 32
IN - India 30
CA - Canada 24
IQ - Iraq 24
NL - Olanda 22
EC - Ecuador 20
ID - Indonesia 19
VE - Venezuela 18
UA - Ucraina 15
ZA - Sudafrica 15
CH - Svizzera 14
CL - Cile 14
PH - Filippine 14
TW - Taiwan 13
ES - Italia 12
TR - Turchia 12
IE - Irlanda 11
MA - Marocco 10
PK - Pakistan 10
RU - Federazione Russa 10
CO - Colombia 9
EG - Egitto 8
PY - Paraguay 8
SE - Svezia 8
KE - Kenya 7
RO - Romania 7
CR - Costa Rica 6
JO - Giordania 6
PL - Polonia 6
SA - Arabia Saudita 6
AT - Austria 5
BG - Bulgaria 5
DK - Danimarca 5
DZ - Algeria 5
LT - Lituania 5
AU - Australia 4
IL - Israele 4
NG - Nigeria 4
SK - Slovacchia (Repubblica Slovacca) 4
TH - Thailandia 4
TN - Tunisia 4
UY - Uruguay 4
BE - Belgio 3
BO - Bolivia 3
CG - Congo 3
CZ - Repubblica Ceca 3
DO - Repubblica Dominicana 3
KR - Corea 3
MM - Myanmar 3
PA - Panama 3
PT - Portogallo 3
RS - Serbia 3
SN - Senegal 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
AZ - Azerbaigian 2
BH - Bahrain 2
CY - Cipro 2
ET - Etiopia 2
GR - Grecia 2
HR - Croazia 2
HU - Ungheria 2
KG - Kirghizistan 2
KW - Kuwait 2
KZ - Kazakistan 2
LB - Libano 2
LV - Lettonia 2
MY - Malesia 2
NO - Norvegia 2
NP - Nepal 2
OM - Oman 2
PE - Perù 2
SI - Slovenia 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
BJ - Benin 1
GA - Gabon 1
GE - Georgia 1
HN - Honduras 1
IR - Iran 1
LA - Repubblica Popolare Democratica del Laos 1
LI - Liechtenstein 1
MD - Moldavia 1
MG - Madagascar 1
MK - Macedonia 1
MT - Malta 1
Totale 34.301
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Città #
Genova 14.772
Genoa 8.746
Rapallo 2.291
Vado Ligure 2.024
Singapore 671
San Jose 569
Ashburn 256
Ho Chi Minh City 214
Lauterbourg 203
Council Bluffs 182
Hanoi 163
Beijing 136
Hong Kong 134
Frankfurt am Main 71
Helsinki 68
Bordighera 63
Los Angeles 56
Santa Clara 53
New York 46
Tokyo 43
Haiphong 39
Mexico City 39
Da Nang 38
Milan 38
Biên Hòa 20
Orem 18
Amsterdam 17
Buffalo 16
Can Tho 16
Cardiff 15
Chicago 14
City of London 14
São Paulo 14
Tianjin 14
Hải Dương 13
Paris 13
Rome 13
Zurich 13
Nuremberg 12
Baghdad 11
Dublin 10
Guangzhou 10
Johannesburg 10
St Louis 10
Atlanta 9
Bắc Ninh 9
London 9
Montreal 9
Turin 9
Guayaquil 8
Kyiv 8
Manchester 8
Phú Thọ 8
Rio de Janeiro 8
Thái Nguyên 8
Brescia 7
Changsha 7
Denver 7
Long Xuyen 7
Quảng Ngãi 7
Thái Bình 7
Amman 6
Ankara 6
Belo Horizonte 6
Ninh Bình 6
Phủ Lý 6
Piscataway 6
Porto Alegre 6
Quito 6
Sacramento 6
San Francisco 6
Cairo 5
Charlotte 5
Dallas 5
Des Moines 5
Dhaka 5
Hangzhou 5
Madrid 5
Nairobi 5
Quezon City 5
Santiago 5
Savona 5
Stockholm 5
Anápolis 4
Asunción 4
Bratislava 4
Chiavari 4
Copenhagen 4
Curitiba 4
Hyderabad 4
Montevideo 4
Salt Lake City 4
San José 4
Schiavon 4
Sydney 4
Toronto 4
Warsaw 4
Điện Bàn 4
Alessandria 3
Antwerp 3
Totale 31.509
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Nome #
Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo 258
APO866 increases antitumor activity of cyclosporin - A by inducing mitochondrial and endoplasmic reticulum stress in leukemia cells 258
Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP-ribose as second messenger. 252
APO866 activity in hematologic malignancies: a preclinical in vitro study. 245
Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells vulnerability to DNA-damaging agents 240
Impaired increase of plasma abscisic acid in response to oral glucose load in type 2 diabetes and in gestational diabetes 230
Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors and DNA repair. 229
Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin. 224
Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics 223
G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2 223
G(s) protein dysfunction in allergen-challenged human isolated passively sensitized bronchi. 222
Catastrophic NAD(+) Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE 216
Abscisic acid ameliorates the systemic sclerosis fibroblast phenotype in vitro. 215
Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis 213
Binding of abscisic acid to human LANCL2 211
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells 211
Abscisic Acid Stimulates Glucagon-Like Peptide-1 Secretion from L-Cells and Its Oral Administration Increases Plasma Glucagon-Like Peptide-1 Levels in Rats 209
Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo 207
LANCL2 is necessary for Abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells 207
Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger. 206
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model 199
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects 199
Tolerability and efficacy study of P2X7 inhibition in experimental Charcot-Marie-Tooth type 1A (CMT1A) neuropathy 199
Abscisic acid and cyclic ADP-ribose are first and second messanger in inflammatory cells, hematopoietic progenitors and pancreatic beta-cells 198
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. 198
ABA says NO to UV-B: a universal response? 197
Inhibition of Nicotinamide Phosphoribosyltransferase Reduces Neutrophil-Mediated Injury in Myocardial Infarction. 197
ABA- and cADPR-mediated effects on respiration and filtration downstream of the temperature-signaling cascade in sponges 196
Discovery of novel and selective SIRT6 inhibitors. 195
The diadenosine homodinucleotide P18 improves in vitro myelination in experimental Charcot-Marie-Tooth type 1A 195
Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody 193
Adenylic dinucleotides produced by CD38 are negative endogenous modulators of platelet aggregation 189
Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration 188
Regulation of human mesenchymal stem cell functions by an autocrine loop involving NAD+ release and P2Y11-mediated signaling. 187
Autocrine abscisic acid mediates the UV-B-induced inflammatory response in human granulocytes and keratinocytes 186
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 186
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. 185
A self restricted CD38-connexin 43 cross-talk affects NAD+ and cyclic ADP-ribose metabolism and regulates intracellular calcium in 3T3 fibroblasts 184
Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules 183
Abscisic acid activates the murine microglial cell line N9 through the second messenger cyclic ADP-ribose 182
Concentrative influx of functionally active cyclic ADP-ribose in dimethylsulfoxide-differentiated HL-60 cells 182
Abscisic acid signaling through cyclic ADP-ribose in hydroid regeneration 178
Abscisic Acid: A Conserved Hormone in Plants and Humans and a Promising Aid to Combat Prediabetes and the Metabolic Syndrome. 178
Extracellular NAD+ regulates intracellular calcium levels and induces activation of human granulocytes 178
Abscisic acid and cyclic ADP-ribose are first and second messengers in inflammatory cells and hemopoietic progenitors 177
The plant hormone abscisic acid stimulates the proliferation of human hemopoietic progenitors through the second messenger cyclic ADP-ribose 177
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice. 177
Mesenchymal stem cells shape microglia effector functions through the release of CX3CL1 176
Cyclic ADP-ribose generation by CD38 improves human hemopoietic stem cell engraftment into NOD/SCID mice 175
Functional characterization of a synthetic abscisic acid analog with anti-inflammatory activity on human granulocytes and monocytes 173
Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors As Therapeutics: Rationales, Controversies, Clinical Experience. 173
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 171
The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting. 170
LANCL2 is the abscisic acid receptor in human granulocytes and in rat insulinoma cells. 169
Concentrative uptake of cyclic ADP-ribose generated by BST-1+ stroma stimulates proliferation of human hematopoietic progenitors 168
Impaired increase of plasma abscisic acid in response to oral glucose load in type 2 diabetes and in gestational diabetes 167
A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes. 166
Subcellular and intercellular traffic of NAD+, NAD+ precursors and NAD+-derived signalmetabolites and second messengers: Old and new topological paradoxes 165
Abscisic acid produced by human monocytes stimulates monocyte and vascular smooth muscle cell responses involved in the development of the atherosclerotic lesion 165
Abscisic Acid: A Novel Nutraceutical for Glycemic Control 165
The danger signal extracellular ATP is involved in the immunomediated damage of α-sarcoglycan deficient muscular dystrophy 164
CD38-Induced Metabolic Dysfunction Primes Multiple Myeloma Cells for NAD+-Lowering Agents 163
Selectivity hot-spots of sirtuin catalytic cores 162
Abscisic acid is an endogenous stimulator of insulin release from human release from human pancreatic islets with cyclic ADP-ribose as second messenger. 161
Abscisic acid enhances adipocyte diffentiation and glucose uptake in murine 3T3-L1 and in human ATMSC 161
Mitochondrial dysfunction induced by a cytotoxic adenine dinucleotide produced by ADP-ribosyl cyclases from cADPR. 161
Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells. 160
Nicotinamide Phosphoribosyltransferase As A Target In Inflammation-Related Disorders. 160
Dimeric and tetrameric forms of catalytically active transmembrane CD38 in transfected HeLa cells 159
Abscisic acid and cyclic ADP-ribose increase intracellular Ca2+ and stimulate proliferation of human mesenchymal stem cells. 159
ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells. 159
Autocrine abscisic acid plays a key role in quartz-induced macrophage activation 158
NAD+ Levels Control Ca2+ Store Replenishment and Mitogen-induced Increase of Cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 Channel Gating in Human T Lymphocytes. 156
Catastrophic NAD+ Depletion through Nampt Inhibition in Activated T Lymphocytes Reduces Demyelination and Disability in EAE. 155
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 155
Expression of CD38 increases intracellular calcium concentration and reduces doubling time in HeLa and 3T3 cells. 154
Synthetic analogues of abscisic acid with anti-inflammatory and insulin release stimulation effects on human cells 154
Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine 154
Abscisic acid produced by human monocyte and vascular smooth muscle cell responses involved in the development of the atherosclerotic lesion. 153
Equilibrative and concentrative nucleoside transporters mediate the influx of Cyclic ADP-ribose into 3T3 murine fibroblasts. 153
NAADP+ synthesis from cADPRP and nicotinic acid by ADP-ribosyl cyclases 151
LANCL2 is the abscisic acid receptor in in human granulocytes and in rat insulinoma cells 151
Toward a medicine-oriented use of the human hormone/nutritional supplement Abscisic Acid 151
Abscisic acid is an endogenous pro-inflammatory cytokine in human granulocytes with cyclic ADP-ribose as second messenger 151
Paracrine roles of NAD+ and Cyclic ADP-ribose in increasing intracellular calcium and enhancing cell proliferation of 3T3 fibroblasts 150
Autocrine and paracrine calcium signalling by the CD38/NAD+/cyclic ADP-ribose system 149
The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism 149
Abscisic acid: a new human adipose tissue-derived hormone? 149
The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts 148
The plant hormone abscisic acid stimulates the proliferation of human hemopoietic progenitors through the second messenger cyclic ADP-ribose. 148
Fluridone as a new anti-inflammatory drug 148
Rejuvenating sirtuins: the rise of a new family of cancer drug targets 148
A P2X7 antagonist improves muscle strength and motor distal amplitude in CMT1A rats: preliminary results from an in vivo trial 147
Amino acid depletion triggered by L-asparaginase sensitizes MM cells to carfilzomib by inducing mitochondria ROS-mediated cell death 146
Abscisic acid and cyclic ADP-ribose increase intracellular Ca++ and stimulate proliferation of human mesenchymal stem cells 145
Cyclic ADP-ribose-mediated expansion and stimulation of human mesenchymal stem cells by the plant hormone abscisic acid 145
Abscisic acid: a new player in cardiomyocyte protection from hypoxia 143
Novel adenylic dinucleotides with anti-tumor activity and method of preparing thereof. 142
Mitochondrial dysfunction induced by a cytotoxic adenine dinucleotide produced by ADP-ribosyl cyclases from cADPR 142
A P2X7 antagonist improves muscle strength and motor distal amplitude in CMT1A rats: preliminary results from an in vivo trial 142
Totale 17.891
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Categoria #
all - tutte 104.688
article - articoli 80.906
book - libri 0
conference - conferenze 20.481
curatela - curatele 0
other - altro 0
patent - brevetti 2.966
selected - selezionate 0
volume - volumi 335
Totale 209.376
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021406 0 0 0 0 0 0 0 0 0 197 110 99
2021/20222.648 72 221 246 280 86 146 178 584 118 248 94 375
2022/20232.769 253 217 43 293 489 404 15 210 443 12 357 33
2023/20241.987 84 195 72 272 186 396 124 118 99 58 128 255
2024/20255.591 303 340 227 427 576 459 502 972 189 292 606 698
2025/20269.335 1.282 294 693 882 1.498 832 1.514 571 845 924 0 0
Totale 34.787