IRIS
BRUZZONE, SANTINA
 Distribuzione geografica
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Continente #
EU - Europa 29.054
AS - Asia 3.773
NA - Nord America 3.135
SA - Sud America 340
AF - Africa 70
OC - Oceania 5
Totale 36.377
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Nazione #
IT - Italia 28.384
US - Stati Uniti d'America 2.942
SG - Singapore 1.453
CN - Cina 932
VN - Vietnam 734
BD - Bangladesh 267
FR - Francia 239
BR - Brasile 195
HK - Hong Kong 149
DE - Germania 93
FI - Finlandia 74
CA - Canada 72
GB - Regno Unito 66
AR - Argentina 61
MX - Messico 55
JP - Giappone 54
IN - India 32
NL - Olanda 29
IQ - Iraq 24
EC - Ecuador 21
ES - Italia 21
VE - Venezuela 20
ID - Indonesia 19
ZA - Sudafrica 16
CH - Svizzera 15
UA - Ucraina 15
CL - Cile 14
PH - Filippine 14
TR - Turchia 13
TW - Taiwan 13
JM - Giamaica 12
PK - Pakistan 12
CO - Colombia 11
CR - Costa Rica 11
IE - Irlanda 11
MA - Marocco 10
PL - Polonia 10
RU - Federazione Russa 10
DK - Danimarca 9
SE - Svezia 9
EG - Egitto 8
PY - Paraguay 8
RO - Romania 8
HN - Honduras 7
KE - Kenya 7
BG - Bulgaria 6
GT - Guatemala 6
JO - Giordania 6
PT - Portogallo 6
SA - Arabia Saudita 6
TH - Thailandia 6
AT - Austria 5
DZ - Algeria 5
LT - Lituania 5
AU - Australia 4
BE - Belgio 4
IL - Israele 4
NG - Nigeria 4
RS - Serbia 4
SK - Slovacchia (Repubblica Slovacca) 4
TN - Tunisia 4
TT - Trinidad e Tobago 4
UY - Uruguay 4
AE - Emirati Arabi Uniti 3
AL - Albania 3
BB - Barbados 3
BO - Bolivia 3
BS - Bahamas 3
CG - Congo 3
CZ - Repubblica Ceca 3
DO - Repubblica Dominicana 3
GR - Grecia 3
HR - Croazia 3
HU - Ungheria 3
KR - Corea 3
MM - Myanmar 3
MY - Malesia 3
NI - Nicaragua 3
PA - Panama 3
PE - Perù 3
SN - Senegal 3
SV - El Salvador 3
AZ - Azerbaigian 2
BH - Bahrain 2
CY - Cipro 2
ET - Etiopia 2
GD - Grenada 2
KG - Kirghizistan 2
KN - Saint Kitts e Nevis 2
KW - Kuwait 2
KZ - Kazakistan 2
LB - Libano 2
LV - Lettonia 2
MK - Macedonia 2
NO - Norvegia 2
NP - Nepal 2
OM - Oman 2
SI - Slovenia 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
Totale 36.357
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Città #
Genova 14.772
Genoa 8.795
Rapallo 2.291
Vado Ligure 2.024
San Jose 716
Singapore 680
Ashburn 368
Ho Chi Minh City 215
Lauterbourg 203
Council Bluffs 182
Beijing 166
Hanoi 165
Hong Kong 138
New York 101
Los Angeles 96
Santa Clara 78
Frankfurt am Main 71
Helsinki 68
Milan 66
Bordighera 64
Tokyo 43
Mexico City 41
Da Nang 40
Haiphong 39
Rome 39
Buffalo 35
Chicago 35
Dallas 33
Naples 22
Houston 21
Orem 21
Biên Hòa 20
Amsterdam 19
Boardman 19
Brooklyn 18
Atlanta 16
Can Tho 16
San Francisco 16
Cardiff 15
Miami 15
Montreal 15
Phoenix 15
City of London 14
São Paulo 14
Tianjin 14
Hải Dương 13
Paris 13
Turin 13
Zurich 13
Denver 12
Nuremberg 12
Baghdad 11
Johannesburg 11
Manchester 11
St Louis 11
Charlotte 10
Dublin 10
Guangzhou 10
Las Vegas 10
London 10
Philadelphia 10
Sacramento 10
Bắc Ninh 9
Piscataway 9
Rio de Janeiro 9
Toronto 9
Guayaquil 8
Kingston 8
Kyiv 8
Phú Thọ 8
The Bronx 8
Thái Nguyên 8
Warsaw 8
Brescia 7
Changsha 7
Columbia 7
Long Xuyen 7
Madrid 7
Porto Alegre 7
Queens 7
Quito 7
Quảng Ngãi 7
San José 7
Thái Bình 7
Vancouver 7
Amman 6
Ankara 6
Baltimore 6
Belo Horizonte 6
Columbus 6
Copenhagen 6
Des Moines 6
Detroit 6
Dhaka 6
Florence 6
Guatemala City 6
Ninh Bình 6
Phủ Lý 6
Stockholm 6
Washington 6
Totale 32.310
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Nome #
APO866 increases antitumor activity of cyclosporin - A by inducing mitochondrial and endoplasmic reticulum stress in leukemia cells 322
Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo 270
Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP-ribose as second messenger. 262
APO866 activity in hematologic malignancies: a preclinical in vitro study. 252
Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells vulnerability to DNA-damaging agents 248
Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors and DNA repair. 243
G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2 242
Impaired increase of plasma abscisic acid in response to oral glucose load in type 2 diabetes and in gestational diabetes 238
Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin. 230
Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics 228
G(s) protein dysfunction in allergen-challenged human isolated passively sensitized bronchi. 226
Binding of abscisic acid to human LANCL2 224
Catastrophic NAD(+) Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE 223
Abscisic acid ameliorates the systemic sclerosis fibroblast phenotype in vitro. 222
Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo 218
Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis 218
Abscisic Acid Stimulates Glucagon-Like Peptide-1 Secretion from L-Cells and Its Oral Administration Increases Plasma Glucagon-Like Peptide-1 Levels in Rats 217
Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger. 215
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells 215
LANCL2 is necessary for Abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells 213
Inhibition of Nicotinamide Phosphoribosyltransferase Reduces Neutrophil-Mediated Injury in Myocardial Infarction. 212
CD38 downregulation modulates NAD+ and NADP(H) levels in thermogenic adipose tissues 210
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. 207
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects 206
ABA- and cADPR-mediated effects on respiration and filtration downstream of the temperature-signaling cascade in sponges 205
Abscisic acid and cyclic ADP-ribose are first and second messanger in inflammatory cells, hematopoietic progenitors and pancreatic beta-cells 204
Discovery of novel and selective SIRT6 inhibitors. 204
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model 204
Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody 203
Tolerability and efficacy study of P2X7 inhibition in experimental Charcot-Marie-Tooth type 1A (CMT1A) neuropathy 203
ABA says NO to UV-B: a universal response? 202
The diadenosine homodinucleotide P18 improves in vitro myelination in experimental Charcot-Marie-Tooth type 1A 200
Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration 198
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. 193
Adenylic dinucleotides produced by CD38 are negative endogenous modulators of platelet aggregation 193
Regulation of human mesenchymal stem cell functions by an autocrine loop involving NAD+ release and P2Y11-mediated signaling. 192
Autocrine abscisic acid mediates the UV-B-induced inflammatory response in human granulocytes and keratinocytes 191
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 191
A self restricted CD38-connexin 43 cross-talk affects NAD+ and cyclic ADP-ribose metabolism and regulates intracellular calcium in 3T3 fibroblasts 189
Abscisic acid activates the murine microglial cell line N9 through the second messenger cyclic ADP-ribose 189
Concentrative influx of functionally active cyclic ADP-ribose in dimethylsulfoxide-differentiated HL-60 cells 189
Extracellular NAD+ regulates intracellular calcium levels and induces activation of human granulocytes 189
Mesenchymal stem cells shape microglia effector functions through the release of CX3CL1 188
Abscisic Acid: A Conserved Hormone in Plants and Humans and a Promising Aid to Combat Prediabetes and the Metabolic Syndrome. 187
Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules 187
The plant hormone abscisic acid stimulates the proliferation of human hemopoietic progenitors through the second messenger cyclic ADP-ribose 186
Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors As Therapeutics: Rationales, Controversies, Clinical Experience. 186
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice. 185
Abscisic acid signaling through cyclic ADP-ribose in hydroid regeneration 184
Abscisic acid and cyclic ADP-ribose are first and second messengers in inflammatory cells and hemopoietic progenitors 184
Functional characterization of a synthetic abscisic acid analog with anti-inflammatory activity on human granulocytes and monocytes 182
Cyclic ADP-ribose generation by CD38 improves human hemopoietic stem cell engraftment into NOD/SCID mice 180
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 179
The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting. 178
Concentrative uptake of cyclic ADP-ribose generated by BST-1+ stroma stimulates proliferation of human hematopoietic progenitors 177
Abscisic acid produced by human monocytes stimulates monocyte and vascular smooth muscle cell responses involved in the development of the atherosclerotic lesion 176
NAD+ METABOLISM RESTRICTION BOOSTS HIGH-DOSE MELPHALAN EFFICACY IN PATIENTS WITH MULTIPLE MYELOMA 175
Subcellular and intercellular traffic of NAD+, NAD+ precursors and NAD+-derived signalmetabolites and second messengers: Old and new topological paradoxes 175
Impaired increase of plasma abscisic acid in response to oral glucose load in type 2 diabetes and in gestational diabetes 175
CD38-Induced Metabolic Dysfunction Primes Multiple Myeloma Cells for NAD+-Lowering Agents 174
LANCL2 is the abscisic acid receptor in human granulocytes and in rat insulinoma cells. 172
Abscisic acid and cyclic ADP-ribose increase intracellular Ca2+ and stimulate proliferation of human mesenchymal stem cells. 171
Nicotinamide Phosphoribosyltransferase As A Target In Inflammation-Related Disorders. 171
Abscisic Acid: A Novel Nutraceutical for Glycemic Control 171
A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes. 171
Selectivity hot-spots of sirtuin catalytic cores 170
Abscisic acid is an endogenous stimulator of insulin release from human release from human pancreatic islets with cyclic ADP-ribose as second messenger. 169
The danger signal extracellular ATP is involved in the immunomediated damage of α-sarcoglycan deficient muscular dystrophy 169
Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells. 168
Abscisic acid enhances adipocyte diffentiation and glucose uptake in murine 3T3-L1 and in human ATMSC 166
ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells. 165
Mitochondrial dysfunction induced by a cytotoxic adenine dinucleotide produced by ADP-ribosyl cyclases from cADPR. 165
Catastrophic NAD+ Depletion through Nampt Inhibition in Activated T Lymphocytes Reduces Demyelination and Disability in EAE. 164
LANCL2 is the abscisic acid receptor in in human granulocytes and in rat insulinoma cells 163
Autocrine abscisic acid plays a key role in quartz-induced macrophage activation 163
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 163
Equilibrative and concentrative nucleoside transporters mediate the influx of Cyclic ADP-ribose into 3T3 murine fibroblasts. 161
Abscisic acid produced by human monocyte and vascular smooth muscle cell responses involved in the development of the atherosclerotic lesion. 160
Expression of CD38 increases intracellular calcium concentration and reduces doubling time in HeLa and 3T3 cells. 159
Dimeric and tetrameric forms of catalytically active transmembrane CD38 in transfected HeLa cells 159
Synthetic analogues of abscisic acid with anti-inflammatory and insulin release stimulation effects on human cells 159
NAD+ Levels Control Ca2+ Store Replenishment and Mitogen-induced Increase of Cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 Channel Gating in Human T Lymphocytes. 159
Amino acid depletion triggered by L-asparaginase sensitizes MM cells to carfilzomib by inducing mitochondria ROS-mediated cell death 158
NAADP+ synthesis from cADPRP and nicotinic acid by ADP-ribosyl cyclases 157
Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine 156
The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism 155
Abscisic acid is an endogenous pro-inflammatory cytokine in human granulocytes with cyclic ADP-ribose as second messenger 155
Toward a medicine-oriented use of the human hormone/nutritional supplement Abscisic Acid 154
Rejuvenating sirtuins: the rise of a new family of cancer drug targets 154
Abscisic acid and cyclic ADP-ribose increase intracellular Ca++ and stimulate proliferation of human mesenchymal stem cells 153
The plant hormone abscisic acid stimulates the proliferation of human hemopoietic progenitors through the second messenger cyclic ADP-ribose. 153
Paracrine roles of NAD+ and Cyclic ADP-ribose in increasing intracellular calcium and enhancing cell proliferation of 3T3 fibroblasts 152
Autocrine and paracrine calcium signalling by the CD38/NAD+/cyclic ADP-ribose system 152
The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts 152
Abscisic acid: a new human adipose tissue-derived hormone? 152
Fluridone as a new anti-inflammatory drug 152
A P2X7 antagonist improves muscle strength and motor distal amplitude in CMT1A rats: preliminary results from an in vivo trial 151
Cyclic ADP-ribose-mediated expansion and stimulation of human mesenchymal stem cells by the plant hormone abscisic acid 150
SIRT6 pharmacological inhibition delays skin cancer progression in the squamous cell carcinoma 148
Abscisic acid: a new player in cardiomyocyte protection from hypoxia 148
Totale 18.748
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Categoria #
all - tutte 114.460
article - articoli 88.245
book - libri 0
conference - conferenze 22.653
curatela - curatele 0
other - altro 0
patent - brevetti 3.208
selected - selezionate 0
volume - volumi 354
Totale 228.920
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.648 72 221 246 280 86 146 178 584 118 248 94 375
2022/20232.769 253 217 43 293 489 404 15 210 443 12 357 33
2023/20241.987 84 195 72 272 186 396 124 118 99 58 128 255
2024/20255.591 303 340 227 427 576 459 502 972 189 292 606 698
2025/202610.609 1.282 294 693 882 1.498 832 1.514 571 845 1.010 604 584
2026/2027796 796 0 0 0 0 0 0 0 0 0 0 0
Totale 36.857