IRIS
BONDAVALLI, FRANCESCO
 Distribuzione geografica
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Continente #
EU - Europa 15.230
AS - Asia 8
SA - Sud America 5
AF - Africa 1
Totale 15.244
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Nazione #
IT - Italia 15.230
BR - Brasile 5
SG - Singapore 5
VN - Vietnam 2
CN - Cina 1
ZA - Sudafrica 1
Totale 15.244
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Città #
Genova 9.467
Genoa 3.470
Rapallo 1.383
Vado Ligure 896
Bordighera 14
Singapore 5
Ho Chi Minh City 2
Belo Horizonte 1
Fazenda Rio Grande 1
Mauá 1
Santo André 1
Stellenbosch 1
Tailândia 1
Totale 15.243
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Nome #
An efficient synthesis of functionalized 2-pyridones by direct route or via amide/enolate ammonium salt intermediates 185
Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines 160
Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors 155
2-Aryl-3-phenylamino-4,5-dihydro-2h-benz[g]indazoles with analgesic activity 155
1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors 153
Synthesis and biological evaluation of neutrophilic inflammation inhibitors 151
3-Arylsulphonyl-5-arylamino-1,3,4-thiadiazol-2(3H)ones as antiinflammatory and analgesic agents 150
Affinity prediction on A1 adenosine receptor agonists: the chemometric approach 150
3,5-Diphenyl-1H-pyrazole derivatives. IX. 2-substituted 4-phenyl-5-(3,5-diphenyl-1H-pyrazol-1-yl) pyrimidines with platelet antiaggregating and other activities. 149
1-Acyl-, 3-acyl- and 1,3-diacyl-3-furfuryl-1-phenylthioureas with platelet antiaggregating and other activities. 149
. 3,5-diphenyl-1H-pyrazole derivatives. XI. N-aryl-5(3)-phenyl-4-(3,5- diphenyl-1-pyrazolyl)-3(5)-pyrazole amines, 5-substituted 4,5-dihydro-3-phenyl-4-(3,5-diphenyl-1-pyrazolyl)-1H-pyrazoles and 2,6-disubstituted 1,6-dihydro-4- phenyl-5-(3,5-diphenyl-1-pyrazolyl)pyrimidines with antipyretic, antiinflammatory and other activities. 148
A chemometric approach to predict A1 agonist effect of adenosine analogues 141
Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line 140
3,5-Diphenyl-1H-pyrazole derivatives. V--1-Acetyl-4-hydroxy-3,5-diphenyl-2-pyrazoline esters, 4-hydroxy-3,5-diphenyl-1H-pyrazole esters and N-substituted 4-(3-amino-2-hydroxy-1-propoxy)-1-methyl-3,5-diphenyl-1H-pyrazoles with antiarrhythmic, sedative and platelet antiaggregating activities. 139
3,5-Diphenyl-1H-pyrazole derivatives. III. Ethers 1-(2-hydroxyethyl)-3,5-diphenyl-1H-pyrazole and its 4-bromo derivative with hypotensive, depressant, antiarrhythmic and analgesic activities 137
N-Acyl-N-phenyl ureas of piperidine and substituted piperidines endowed with antiinflammatory and antiproliferative activities 136
Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis 136
3,3-disubstituted 1-acyl-1-phenylthioureas with platelet antiaggregating and other activities 135
Antiinflammatory agents: new series of N-substituted amino acids with complex pyrimidine structures endowed with antiphlogistic activity 133
Synthesis and reactivity of (1S,4S,5S) -5-bromo-1,3,3-trimethyl-N-nitro-2-oxabicyclo[2.2.2]octan-6-imine. X Ray-molecular structure and absolute configuration of E and Z isomers of (1S,4S)-5,5-dibromo-1,3,3-trimethyl-N-nitro-2-oxabicyclo[2.2.2]octan-6-imine, the first case of separated nitrimine isomers. 132
Synthesis and pharmacological activity of derivatives of exo- trimethylenenorbornane. I 130
Synthesis and pharmacological evaluation of 5H-[1]benzopyrano[4,3-d]pyrimidines effective as antiplatelet/analgesic agents 130
N-acyl-N'-methyl-N-(1,3,3-trimethylbicyclo[2.2.1]hept-2-yl) benzamidines with hypotensive activity. 129
N'-acyl-N,N-(1,3,3-trimethylbicyclo [2.2.1]hept-2-ylidene)benzamidines with hypotensive activity. 129
2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole derivatives: New potent inhibitors of fMLP-induced neutrophil chemotaxis 128
3-(Arylamino)-6,7-dihydro-6-methylpyrano[4,3-c]pyrazol-4(1H or 2H)-ones with antipyretic, analgesic, antiarrhythmic, hypotensive and other activities. 126
2- And 5-substituted 5-amino-2,6,6-trimethyltetrahydropyrans 126
Synthesis, molecular modeling studies and pharmacological activity of selective A1 receptor antagonists 125
Carbonyl transposition and regio- and stereo-specific syntheses of new alcohols, amino-alcohols and ketones in the monoterpenoid 1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane 125
2-aryl-3-phenylamino-4,5-dihydro-2H-benz[g]indazoles with antiarrhythmic and local anaesthetic activities 124
Derivati dell'1,3-benzodiossolo, potenziali inibitori delle PDE5 123
New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation 123
omega-Dialkylaminoalkyl esters of 3-dialkylamino-4,7,7-trimethyl-N-phenylbicyclo[2.2.1] hept-2-ene-2-iminothiolic acids with local anesthetic activity. 121
3,5-Diphenyl-1H-pyrazole derivatives. I--Esters and N-substituted carbamates of 1-(2-hydroxyethyl)-3,5-diphenyl-1H-pyrazole and its 4-bromo derivative with depressant, antiarrhythmic, analgesic and other activities. 120
Preparation of new 5-aroylamino substituted 3-nicotinoyl/isonicotinoyl-1,3,4-thiadiazol-2(3H)-ones with anti-inflammatory activity 120
2-Amino/Azido/Hydrazino-5-alkoxy-5H-[1]benzopyrano[4,3-d]pyrimidines: Synthesis and Pharmacological Evaluation 120
Synthesis and pharmacological evaluation of 2,5-Cycloamino-5H[1]benzopyrano[4,3-d]pyrimidines endowed with in vitro antiplatelet activity 120
3,5-Diphenyl-1H-pyrazole derivatives. IV--N,N-disubstituted 3-(3,5-diphenyl-1H-pyrazol-1-yl)propanamides and 3-(3,5-diphenyl-1H-pyrazol-1-yl)propanamines with sedative, platelet antiaggregating and local anesthetic activities. 119
null 117
New 1,3,4-thiadiazole derivatives endowed with analgesic and anti-inflammatory activities 117
3,5-Diphenyl-1H-pyrazole derivatives. II--N-substituted 1-(2-aminoethyl)-3,5-diphenyl-1H-pyrazoles and their 4-bromo derivatives with analgesic and other activities 116
null 116
Exploring the molecular basis of selectivity in A1 adenosine receptors antagonist: a case study 116
Unprecedented one-pot stereoselective synthesis of Knoevenagel-type derivatives via in situ condensation of N-methyleniminium salts of ethylenethiourea and ethyleneurea with active methylene reagents 115
Synthesis and anti-inflammatory activity of esters derived from 5-aryl-1,2-dihydro-2-(2-hydroxyethyl)-3H-1,2,4-triazole-3-thiones 115
Antiangiogenic agents: an update on small molecule VEGFR inhibitors 114
3,5-Diphenyl-1H-pyrazole derivatives. VI Esters and 2-dialkylaminoethyl ethers of 1(2-hydroxy-2-phenylethyl)-3,5-diphenyl-1H-pyrazole and N,N-disubstituted 1-(2-amino-2-phenylethyl)-3,5-diphenyl-1H-pyrazoles with depressant and platelet antiaggregating activities. 114
Synthesis of 1-(2-chloro-2-phenylethyl)-6-methylthio-1-H-pyrazolo[3,4-d]pyrimidines 4-amino substituted and their biological evaluation 113
Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells 113
2-Aryl-6-methyl-3-phenylamino-6,7-dihydropyrano[4,3-c]pyrazol-4(2H)-ones with analgesic activity. 113
The reaction of Terpenoid Nitrimines with secondary amines; a new route to Terpenoid Enamines 113
New halogenated 4-aminopyrazolo[3,4-b]pyridines A1 adenosine receptor ligands 112
Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation 112
Substituted pyrazolo[3,4-b]pyridines as potent A1 adenosine antagonists: synthesis, biological evaluation, and development of an A1 bovine receptor model. 111
Synthesis, antiplatelet and antithrombotic activities of new 2-substituted benzopyrano[4,3-d]pyrimidin-4-cycloamines and 4-amino/cycloamino-benzopyrano[4,3-d]pyrimidin-5-ones  109
3,5-Diphenyl-1H-pyrazole derivatives. VII--Esters, 2-dialkylaminoethyl ethers and N-substituted carbamates of 1-(2-hydroxy-3-phenoxypropyl)-3,5-diphenyl-1H-pyrazole with depressant and platelet antiaggregating activities 109
Synthesis of 6-thiosubstituted 5-ethoxycarbonyl-1,3-diphenyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-ones, 6-substituted 5-hydroxy-1,3-diphenyl-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-ones and their esters with local anesthetic, antiarrhythmic, antiinflammatory and analgesic activities. 109
4-Amino-pyrazolo[3,4-d]pyrimidines with antiproliferative activity on osteosarcoma cell line SaOS-2 108
Derivatives of 4,5,6,7-Tetrahydro-7,8,8-trimethyl-3-phenylamino-4,7-methano-2H-Indazole with hypoglycemic and hypotensive activities 107
5-alkoxy-2-hydrazino and 5-methoxy-2-amino-5H-[1]benzopyrano[4,3-d]pyrimidines: synthesis and pharmacological activity 107
3,5-Diphenyl-1H-pyrazole derivatives. XII. N-substituted 4-amino-1-(2-hydroxy- or 2-alkylaminoethyl)-3,5-diphenyl-1H-pyrazoles with local anesthetic, analgesic and platelet antiaggregating activities. 107
Structure-based Design, Parallel Synthesis, SAR and Molecular Modelling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea Derivatives. 106
3,5-Diphenyl-1H-pyrazole derivatives. VIII. N-substituted 3-(4-hydroxy-3,5-diphenyl-1H-pyrazol-1-yl)-propanamides, -propanamines and 2-(4-hydroxy-3,5-diphenyl-1H-pyrazol-1-yl)ethanamines with platelet antiaggregating, hypotensive, antiarrhythmic and other activities. 106
N-Substituted O-(3-amino-2-hydroxypropyl)oximes of 1,3,3-trimethyl-5-endo-(1-piperidinyl or 4-morpholinyl)-2-oxabicyclo[2.2.2]octan-6-ones with platelet antiaggregating and local anesthetic activities 106
Design, synthesis, SAR, and molecular modeling studies of acylthiocarbamates: a novel series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors structurally related to phenethylthiazolylthiourea derivatives 105
4-Amino-substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and their preparation, pharmaceutical composistion and use antitumor and antileukemic agents 105
Synthesis and biological data of 4-amino-1-(2-chloro-2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl esters, a new series of A1-adenosine receptor (A1AR) ligands 104
O-[2-Hydroxy-3-(dialkylamino)propyl]ethers of (+)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one oxime (camphor oxime) with analgesic and antiarrhythmic activities 104
2,3-Dihydro-1H-imidazo[1,2-b]pyrazole derivatives as potential neutrophils functions inhibitors 103
5-[[ω-(Dialkylamino)alkoxy]methylene]-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ones with hypotensive, local anesthetic, antiarrhythmic and other activities 103
null 102
null 101
N-arylsubstituted-1-aryl-3,4-diphenyl-5-pyrazole amines with analgesic and antiarrhythmic properties. 101
Progress in 5H-[1]benzopyrano[4,3-d]pyrimidin-5-amine series: 2-methoxy derivatives effective as antiplatelet agents with analgesic activity 101
N-acyl-4,7,7-trimethyl-N-phenyl-3-(1-piperidinyl or dimethylamino)bicyclo[2.2.1]hept-2-ene-2-carbothioamides with platelet antiaggregating and other activities. 101
New pyrazolo[3,4-b]pyridones as selective A1 adenosine receptor antagonists: synthesis, biological evaluation and molecular modeling studies 100
Derivatives of 5,7,7-trimethyl-6-oxa-3-azabicyclo[3.2.2]nonane with antiarrhythmic, local anesthetic and hypotensive activities. II 100
Bamford-Stevens reaction of (+)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-one p-tolylsulphonylhydrazone 99
N-Monosubstituted Urethanes and Esters of 6-cis-Dimethylamino-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-5-trans-ol with hypotensive and other activities 99
N-Substituted 3-(arylamino)-4,5-dihydro-2H-benz[g]indazol-2-yl acetamides with antiinflammatory and analgesic activities 98
New pyrazolo[3,4-d]pyrimidines 4-benzylamino substituted endowed with antiproliferative activity on chronic myeloid leukemia cell line 98
5-Substituted 2,3-dihydro-6-mercapto-1,3-diphenyl-2-thioxo-4(3H)-pyrimidinones and their 6-(acylthio) derivatives with platelet antiaggregating, antiinflammatory, antiarrhythmic, antihyperlipidemic and other activities. 98
New rolipram related PDE4 inhibitors: synthesis, enantiomers separation and enzymatic activity 97
Synthesis of new 2-phenyl-1-arylcarbamoyl-2,3-dihydro-1h-imidazo[1,2-b]pyrazoles 7-substituted as potential neutrophil chemotaxis inhibitors 97
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines 97
Synthesis of 3-Cyclopentyloxy-4-methoxy-N-(cycloalkylamino-1-yl)-benzamides and related compounds as new Rolipram-analogues 96
Derivatives of 5,7,7-trimethyl-6-oxa-3-azabicyclo[3.2.2]nonane with antiarrhythmic, local anesthetic and hypotensive activities 96
Reduction of 6-hydroxyimino-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane and nitrosation of the resulting amines. New rearrangement products of the monoterpenoid 1,3,3-trimethyl-2-oxabicyclo [2.2.2]octane 96
Synthesis of new pyrazolo [3,4-d]pyrimidines Bcr-Abl tyrosine kinase inhibitors 95
ω-Dialkylaminoalkyl ethers of 6-(benzyl or phenyl)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ol with platelet antiaggregating and local anesthetic activities 95
N-Monosubstituted Urethanes of 6-cis-Dialkylamino-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-5-trans-ols with hypotensive and other activities 95
Reactions of the potassium salt of 1,7,7-trimethyl-N-nitrobicyclo[2.2.1] heptan-2-imine with bromine and nitrous acid: Synthesis of 3-exo-bromo-1,7,7-trimethyl-N-nitrobicyclo[2.2.1]heptan-2-imine, 3-endo-bromo-1,7,7-trimethyl-N-nitrobicyclo[2.2.1]heptan-2-imine, 1,7,7-trimethyl-N-nitro-3-nitrosobicyclo[2.2.1]hept-2-en-2-amine and their reactions with nitrogen nucleophiles. 95
Modulazioni Strutturali in O-[2-(N-Ftalimmido)etil] Acil(Aril)Tiocarbammati, Inibitori Non-Nucleosidici della Transcrittasi Inversa di HIV-1 94
Synthesis of pyrazolo[3,4-d]pyridines selective antagonists of A1 adenosine receptors 94
New selective PDE4D inhibitors able to discriminate between long, short and supershort isoforms 94
O-[ω-(dialkylamino)alkyl]oximes of (+)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one with hypotensive, antiinflammatory, analgesic, local anesthetic and other activities 94
Esters of 6-Cis-dialkyilamino-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-5-trans-ols with hypotensive and other activities 94
Derivatives of 1,3,3-Trimethyl-6-azabicyclo[3.2.1]octane with hypotensive activity 94
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 93
3-Hydroxyiminocamphornitrimine and Camphorquinone Dinitrimine, Compounds previously described as N-Nitro-3-nitrosocamphorenamine.and N-Nitro-N,3-Dinitrosocamphorenamine. Crystal Structure of Camphorquinone Dinitrimine. 93
Totale 11.604
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Categoria #
all - tutte 48.400
article - articoli 39.130
book - libri 0
conference - conferenze 7.815
curatela - curatele 0
other - altro 0
patent - brevetti 1.455
selected - selezionate 0
volume - volumi 0
Totale 96.800
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021461 0 0 0 28 26 72 29 36 79 41 67 83
2021/20221.646 31 154 95 250 54 110 158 348 40 128 79 199
2022/20231.667 181 101 16 170 320 307 0 113 275 11 152 21
2023/2024808 39 134 12 100 76 159 30 27 57 7 43 124
2024/20252.196 33 185 66 164 285 240 141 331 85 93 242 331
2025/20261.120 524 87 256 253 0 0 0 0 0 0 0 0
Totale 15.349