IRIS
NENCIONI, ALESSIO
 Distribuzione geografica
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Continente #
EU - Europa 28.441
NA - Nord America 4.091
AS - Asia 3.672
Continente sconosciuto - Info sul continente non disponibili 577
SA - Sud America 351
AF - Africa 79
OC - Oceania 11
Totale 37.222
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Nazione #
IT - Italia 27.782
US - Stati Uniti d'America 3.794
SG - Singapore 1.362
CN - Cina 877
VN - Vietnam 638
BD - Bangladesh 386
FR - Francia 236
BR - Brasile 199
CA - Canada 137
HK - Hong Kong 137
DE - Germania 98
FI - Finlandia 81
AR - Argentina 64
GB - Regno Unito 59
JP - Giappone 51
MX - Messico 42
NL - Olanda 36
IN - India 33
IQ - Iraq 30
CH - Svizzera 25
ES - Italia 25
EC - Ecuador 24
JM - Giamaica 23
PH - Filippine 21
ZA - Sudafrica 21
CR - Costa Rica 19
ID - Indonesia 18
TR - Turchia 18
CO - Colombia 17
PK - Pakistan 17
CL - Cile 14
IE - Irlanda 13
RU - Federazione Russa 13
UA - Ucraina 13
TT - Trinidad e Tobago 12
EG - Egitto 11
GT - Guatemala 11
MA - Marocco 11
SA - Arabia Saudita 11
TH - Thailandia 11
VE - Venezuela 11
AU - Australia 10
HN - Honduras 10
KE - Kenya 9
PY - Paraguay 8
UZ - Uzbekistan 8
PE - Perù 7
PL - Polonia 7
SE - Svezia 7
TW - Taiwan 7
AT - Austria 6
DZ - Algeria 6
LT - Lituania 6
SV - El Salvador 6
AE - Emirati Arabi Uniti 5
AL - Albania 5
LB - Libano 5
NI - Nicaragua 5
NP - Nepal 5
PA - Panama 5
TN - Tunisia 5
BB - Barbados 4
BG - Bulgaria 4
BS - Bahamas 4
BZ - Belize 4
DO - Repubblica Dominicana 4
GR - Grecia 4
HR - Croazia 4
MY - Malesia 4
PT - Portogallo 4
AF - Afghanistan, Repubblica islamica di 3
AZ - Azerbaigian 3
BE - Belgio 3
GD - Grenada 3
JO - Giordania 3
KR - Corea 3
SC - Seychelles 3
UY - Uruguay 3
BO - Bolivia 2
DK - Danimarca 2
KZ - Kazakistan 2
OM - Oman 2
PR - Porto Rico 2
PS - Palestinian Territory 2
RO - Romania 2
AM - Armenia 1
AO - Angola 1
BH - Bahrain 1
BY - Bielorussia 1
CG - Congo 1
CI - Costa d'Avorio 1
CU - Cuba 1
CW - ???statistics.table.value.countryCode.CW??? 1
ET - Etiopia 1
GA - Gabon 1
GE - Georgia 1
GF - Guiana Francese 1
GM - Gambi 1
GN - Guinea 1
GP - Guadalupe 1
Totale 36.622
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Città #
Genova 14.599
Genoa 8.252
Rapallo 2.288
Vado Ligure 1.896
San Jose 845
Singapore 649
Ashburn 470
Ho Chi Minh City 204
Lauterbourg 200
Beijing 170
Hanoi 159
New York 158
Hong Kong 129
Council Bluffs 120
Los Angeles 96
Santa Clara 95
Milan 90
Frankfurt am Main 77
Helsinki 74
Phoenix 60
Rome 60
Chicago 59
Dallas 47
Tokyo 45
Bordighera 44
Buffalo 43
Montreal 41
Turin 32
Mexico City 30
Boardman 26
Da Nang 25
Haiphong 25
Houston 25
Zurich 23
Orem 22
St Louis 21
Brooklyn 20
Philadelphia 19
Atlanta 17
Naples 17
São Paulo 17
San José 16
Seattle 16
Tianjin 16
Amsterdam 15
Bologna 15
City of London 15
Biên Hòa 14
Brasília 14
Columbus 14
Florence 14
Jacksonville 14
Miami 14
Newark 14
Baghdad 13
Denver 13
Kingston 13
Washington 13
Bari 12
Charlotte 12
Dublin 12
Johannesburg 12
Las Vegas 12
San Francisco 12
Cardiff 11
Toronto 11
Des Moines 10
London 10
Quito 10
Can Tho 9
Cleveland 9
Guatemala City 9
Nuremberg 9
Rio de Janeiro 9
Tampa 9
Kyiv 8
Paris 8
Phủ Lý 8
Queens 8
The Bronx 8
Ancona 7
Birmingham 7
Boston 7
Detroit 7
Guangzhou 7
Hải Dương 7
New Orleans 7
Ninh Bình 7
Quảng Ngãi 7
Valenza 7
Virginia Beach 7
Alexandria 6
Austin 6
Buenos Aires 6
Cairo 6
Chaguanas 6
Guayaquil 6
Hamilton 6
La Plata 6
Lappeenranta 6
Totale 31.881
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Nome #
Clinical characteristics, management and in-hospital mortality of patients with COVID-19 In Genoa, Italy 355
APO866 increases antitumor activity of cyclosporin - A by inducing mitochondrial and endoplasmic reticulum stress in leukemia cells 331
Fasting and cancer: molecular mechanisms and clinical application 297
Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies. 295
1222 POSTER Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 266
APO866 activity in hematologic malignancies: a preclinical in vitro study. 257
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of AKT-mediated gene repression 255
Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells vulnerability to DNA-damaging agents 253
1221 POSTER Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 251
Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors and DNA repair. 250
Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation 250
Autophagy in blood cancers: biological role and therapeutic implications. 246
Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin. 239
An emerging role of glucagon-like Peptide-1 in preventing advanced-glycation-end-product-mediated damages in diabetes. 238
The vulnerable coronary plaque: update on imaging technologies. 232
Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics 231
Catastrophic NAD(+) Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE 230
Simulation-Based Education for Physicians to Increase Oral Anticoagulants in Hospitalized Elderly Patients with Atrial Fibrillation 229
Update on cardiotoxicity of anti-cancer treatments 226
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells 222
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial 219
Inhibition of Nicotinamide Phosphoribosyltransferase Reduces Neutrophil-Mediated Injury in Myocardial Infarction. 214
Proteasome inhibitors as immunosuppressants: biological rationale and clinical experience. 212
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. 212
Ras-induced resistance to lapatinib is overcome by MEK inhibition 210
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model 209
Sirt6 regulates dendritic cell differentiation, maturation, and function 208
Discovery of novel and selective SIRT6 inhibitors. 207
Reverse-transcriptase polymerase chain reaction of the maspin gene in the detection of bone marrow breast carcinoma cell contamination. 207
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects 207
Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells 206
ANTITUMOR ACTIVITY OF NAMPT INHIBITION AND SYNERGY WITH CYCLOSPORIN A AND HDACIS TO PROMOTE APOPTOSIS IN PRIMARY LEUKEMIC CELLS 206
Amnestic mild cognitive impairment and conversion to Alzheimer's disease: insulin resistance and glycoxidation as early biomarker clusters. 205
Fasting potentiates the anticancer activity of tyrosin kinase inhibitors by strenghtening MAPK signalling inhibition. 204
Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration 204
Anticancer vaccination strategies. 202
Delirium, Frailty, and Fast-Track Surgery in Oncogeriatrics: Is There a Link? 202
Diminazene enhances stability of atherosclerotic plaques in ApoE-deficient mice 202
Molecular diagnosis and monitoring of chronic myelogenous leukemia: BCR-Abl and more. 199
The In-Hospital Length of Stay after Hip Fracture in Octogenarians: Do Delirium and Dementia Shape a New Care Process? 198
Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes. possible relevance to the assays for the detection of micrometastatic breast cancer 197
Algoplus®Scale in Older Patients with Dementia: A Reliable Real-World Pain Assessment Tool 197
Pegfilgrastim compared with filgrastim after autologous peripheral blood stem cell transplantation in patients with solid tumours and lymphomas. 196
Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules 196
Monoclonal antibodies for non-Hodgkin's lymphoma: state of the art and perspectives. 195
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. 195
Pathophysiological role of neutrophils in acute myocardial infarction. 194
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 194
Use of oral anticoagulant drugs in older patients with atrial fibrillation in internal medicine wards 193
Patient-tailored treatments with anti-EGFR monoclonal antibodies in advanced colorectal cancer: KRAS and beyond. 191
Treatment with KLEPTOSE® CRYSMEB reduces mouse atherogenesis by impacting on lipid profile and Th1 lymphocyte response 191
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice. 190
Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors As Therapeutics: Rationales, Controversies, Clinical Experience. 188
Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 187
Peripheral blood vs. bone marrow for molecular monitoring of BCR-ABL1 levels in chronic myelogenous leukemia, a retrospective analysis in allogeneic bone marrow recipients. 187
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition 187
Appropriateness of prescription of oral anticoagulant therapy in acutely hospitalized older people with atrial fibrillation. Secondary analysis of the SIM-AF cluster randomized clinical trial 187
Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments. Concordance with experimental results. 186
Appropriateness of oral anticoagulant therapy prescription and its associated factors in hospitalized older people with atrial fibrillation 186
Evaluating treatment response of chronic myeloid leukemia: emerging science and technology. 185
Carvedilol Prevents Doxorubicin-induced Free Radical release and Oxidative Damage in Cardiomyocytes. 185
Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA 184
NAD+ METABOLISM RESTRICTION BOOSTS HIGH-DOSE MELPHALAN EFFICACY IN PATIENTS WITH MULTIPLE MYELOMA 183
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 183
Frailty assessment in elective gastrointestinal oncogeriatric surgery: Predictors of one-year mortality and functional status 183
CD38-Induced Metabolic Dysfunction Primes Multiple Myeloma Cells for NAD+-Lowering Agents 182
Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols. 182
Hedgehog Signaling Is Useful as a Novel Molecular Marker for Predicting Relapse and Resistance During Chronic Myeloid Leukemia Treatment 182
Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells. 182
The new small tyrosine-kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs 182
Systems medicine in oncology: Signaling network modeling and new-generation decision-support systems 181
Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer 178
Activation of the death receptor apoptosis pathway by TRAIL overcomes anticancer drug resisitance in antiapoptotic bcl-2 family members expressing lymphoma cells 178
Nicotinamide Phosphoribosyltransferase As A Target In Inflammation-Related Disorders. 178
Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer 178
Evaluation of prognostic indices in elderly hospitalized patients 178
Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum. 176
Abstract CT075: Fasting-mimicking diet and hormone therapy modulates metabolic factors to promote breast cancer regression and reduce side effects 175
Clinical characteristics, management and in-hospital mortality of patients with coronavirus disease 2019 in Genoa, Italy 175
The effect of preoperative chemoradiotherapy on lymph nodes harvested in TME for rectal cancer. 174
Treatment with Angiotensin-(1-7) reduces inflammation in carotid atherosclerotic plaques. 173
Dual NAMPT and BTK targeting leads to synergistic killing of Waldenström macroglobulinemia cells regardless of MYD88 and CXCR4 somatic mutation status 173
Selectivity hot-spots of sirtuin catalytic cores 171
Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells 170
The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level 170
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 170
Predictive values of two frailty screening tools in older patients with solid cancer: a comparison of SAOP2 and G8 170
Proteasome inhibitor-induced apoptosis in human monocyte-derived dendritic cells. 169
Catastrophic NAD+ Depletion through Nampt Inhibition in Activated T Lymphocytes Reduces Demyelination and Disability in EAE. 169
Role of genotype-based approach in the clinical management of adult acute myeloid leukemia with normal cytogenetics. 168
Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status 168
Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis 166
Safety and feasibility of fasting‐mimicking diet and effects on nutritional status and circulating metabolic and inflammatory factors in cancer patients undergoing active treatment 166
The use of dendritic cells in cancer immunotherapy. 165
Aromatase inhibitor-induced bone loss osteosarcopenia in older patients with breast cancer: effects of the RANK/RANKL system’s inhibitor denosumab vs. bisphosphonates 164
Amino acid depletion triggered by L-asparaginase sensitizes MM cells to carfilzomib by inducing mitochondria ROS-mediated cell death 164
Immunotherapy with dendritic cells for cancer 163
vitamin C, aging and Alzheimer's disease 162
NAD+ Levels Control Ca2+ Store Replenishment and Mitogen-induced Increase of Cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 Channel Gating in Human T Lymphocytes. 162
HDAC INHIBITORS SYNERGISTICALLY ENHANCE AP0866 ACTIVITY IN HUMAN LEUKEMIA CELLS: EVIDENCE FOR CONVERGING MECHANISMS OF SIRT1 INHIBITION 159
Totale 20.049
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Categoria #
all - tutte 122.681
article - articoli 116.799
book - libri 0
conference - conferenze 2.719
curatela - curatele 0
other - altro 0
patent - brevetti 2.215
selected - selezionate 0
volume - volumi 948
Totale 245.362
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.301 0 0 172 338 116 201 133 534 132 249 121 305
2022/20232.793 279 268 35 310 475 387 14 198 414 54 315 44
2023/20241.747 57 178 57 252 189 309 116 115 70 33 109 262
2024/20255.318 234 338 115 405 596 468 515 974 215 270 522 666
2025/202610.465 1.209 325 652 764 1.351 756 1.426 568 789 1.137 728 760
2026/20271.888 904 358 626 0 0 0 0 0 0 0 0 0
Totale 37.222