IRIS
NENCIONI, ALESSIO
 Distribuzione geografica
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Continente #
EU - Europa 28.300
AS - Asia 3.627
NA - Nord America 3.340
Continente sconosciuto - Info sul continente non disponibili 573
SA - Sud America 303
AF - Africa 78
OC - Oceania 10
Totale 36.231
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Nazione #
IT - Italia 27.668
US - Stati Uniti d'America 3.103
SG - Singapore 1.362
CN - Cina 863
VN - Vietnam 634
BD - Bangladesh 381
FR - Francia 235
BR - Brasile 179
HK - Hong Kong 132
CA - Canada 119
DE - Germania 91
FI - Finlandia 81
AR - Argentina 61
JP - Giappone 50
GB - Regno Unito 48
MX - Messico 41
IN - India 33
NL - Olanda 32
IQ - Iraq 30
CH - Svizzera 25
ES - Italia 23
ZA - Sudafrica 21
PH - Filippine 20
EC - Ecuador 17
ID - Indonesia 16
PK - Pakistan 16
TR - Turchia 16
JM - Giamaica 14
CL - Cile 13
IE - Irlanda 13
RU - Federazione Russa 13
UA - Ucraina 13
MA - Marocco 11
CR - Costa Rica 10
EG - Egitto 10
GT - Guatemala 10
TH - Thailandia 10
AU - Australia 9
KE - Kenya 9
SA - Arabia Saudita 9
CO - Colombia 8
PY - Paraguay 8
UZ - Uzbekistan 8
PE - Perù 7
PL - Polonia 7
SE - Svezia 7
TW - Taiwan 7
DZ - Algeria 6
AL - Albania 5
AT - Austria 5
HN - Honduras 5
LT - Lituania 5
PA - Panama 5
TN - Tunisia 5
TT - Trinidad e Tobago 5
AE - Emirati Arabi Uniti 4
BB - Barbados 4
BG - Bulgaria 4
DO - Repubblica Dominicana 4
GR - Grecia 4
HR - Croazia 4
LB - Libano 4
NI - Nicaragua 4
NP - Nepal 4
PT - Portogallo 4
SV - El Salvador 4
VE - Venezuela 4
AF - Afghanistan, Repubblica islamica di 3
AZ - Azerbaigian 3
BE - Belgio 3
BS - Bahamas 3
JO - Giordania 3
KR - Corea 3
SC - Seychelles 3
UY - Uruguay 3
BO - Bolivia 2
BZ - Belize 2
DK - Danimarca 2
GD - Grenada 2
MY - Malesia 2
OM - Oman 2
PS - Palestinian Territory 2
RO - Romania 2
AO - Angola 1
BH - Bahrain 1
BY - Bielorussia 1
CG - Congo 1
CI - Costa d'Avorio 1
ET - Etiopia 1
GA - Gabon 1
GE - Georgia 1
GF - Guiana Francese 1
GM - Gambi 1
GN - Guinea 1
GP - Guadalupe 1
HU - Ungheria 1
KG - Kirghizistan 1
KH - Cambogia 1
KN - Saint Kitts e Nevis 1
KW - Kuwait 1
Totale 35.639
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Città #
Genova 14.599
Genoa 8.244
Rapallo 2.288
Vado Ligure 1.896
San Jose 714
Singapore 649
Ashburn 404
Ho Chi Minh City 202
Lauterbourg 200
Beijing 165
Hanoi 159
New York 150
Hong Kong 124
Council Bluffs 118
Los Angeles 85
Santa Clara 84
Frankfurt am Main 74
Helsinki 74
Milan 66
Rome 47
Tokyo 45
Bordighera 44
Chicago 42
Buffalo 39
Montreal 38
Dallas 36
Mexico City 30
Turin 29
Da Nang 25
Haiphong 25
Boardman 24
Zurich 23
Phoenix 22
Houston 21
Orem 21
St Louis 21
São Paulo 17
Brooklyn 16
Naples 16
Tianjin 16
Amsterdam 15
Atlanta 15
City of London 15
Biên Hòa 14
Bologna 14
Baghdad 13
Jacksonville 13
Dublin 12
Johannesburg 12
Miami 12
Seattle 12
Cardiff 11
Columbus 11
Florence 11
Newark 11
Philadelphia 11
Washington 11
Bari 10
Charlotte 10
Denver 10
Des Moines 10
Las Vegas 10
Toronto 10
Can Tho 9
Kingston 9
London 9
Cleveland 8
Guatemala City 8
Kyiv 8
Phủ Lý 8
Rio de Janeiro 8
Ancona 7
Birmingham 7
Guangzhou 7
Hải Dương 7
Ninh Bình 7
Paris 7
Quảng Ngãi 7
San José 7
Tampa 7
The Bronx 7
Valenza 7
Alexandria 6
Buenos Aires 6
Detroit 6
La Plata 6
Lappeenranta 6
Louisville 6
Madrid 6
Melbourne 6
Minneapolis 6
Mumbai 6
Nairobi 6
Nuremberg 6
Palermo 6
Panama City 6
Pittsburgh 6
Quito 6
San Francisco 6
Santiago 6
Totale 31.417
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Nome #
Clinical characteristics, management and in-hospital mortality of patients with COVID-19 In Genoa, Italy 345
APO866 increases antitumor activity of cyclosporin - A by inducing mitochondrial and endoplasmic reticulum stress in leukemia cells 326
Fasting and cancer: molecular mechanisms and clinical application 282
Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies. 279
1222 POSTER Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 262
APO866 activity in hematologic malignancies: a preclinical in vitro study. 252
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of AKT-mediated gene repression 252
Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells vulnerability to DNA-damaging agents 250
1221 POSTER Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 248
Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors and DNA repair. 245
Autophagy in blood cancers: biological role and therapeutic implications. 241
Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation 241
Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin. 232
The vulnerable coronary plaque: update on imaging technologies. 231
An emerging role of glucagon-like Peptide-1 in preventing advanced-glycation-end-product-mediated damages in diabetes. 231
Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics 230
Update on cardiotoxicity of anti-cancer treatments 226
Catastrophic NAD(+) Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE 226
Simulation-Based Education for Physicians to Increase Oral Anticoagulants in Hospitalized Elderly Patients with Atrial Fibrillation 225
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial 218
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells 217
Inhibition of Nicotinamide Phosphoribosyltransferase Reduces Neutrophil-Mediated Injury in Myocardial Infarction. 213
Proteasome inhibitors as immunosuppressants: biological rationale and clinical experience. 210
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model 207
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. 207
Ras-induced resistance to lapatinib is overcome by MEK inhibition 206
Discovery of novel and selective SIRT6 inhibitors. 206
Reverse-transcriptase polymerase chain reaction of the maspin gene in the detection of bone marrow breast carcinoma cell contamination. 206
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects 206
Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells 204
Sirt6 regulates dendritic cell differentiation, maturation, and function 202
Delirium, Frailty, and Fast-Track Surgery in Oncogeriatrics: Is There a Link? 202
Diminazene enhances stability of atherosclerotic plaques in ApoE-deficient mice 201
Anticancer vaccination strategies. 200
Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration 200
Amnestic mild cognitive impairment and conversion to Alzheimer's disease: insulin resistance and glycoxidation as early biomarker clusters. 199
ANTITUMOR ACTIVITY OF NAMPT INHIBITION AND SYNERGY WITH CYCLOSPORIN A AND HDACIS TO PROMOTE APOPTOSIS IN PRIMARY LEUKEMIC CELLS 199
The In-Hospital Length of Stay after Hip Fracture in Octogenarians: Do Delirium and Dementia Shape a New Care Process? 198
Fasting potentiates the anticancer activity of tyrosin kinase inhibitors by strenghtening MAPK signalling inhibition. 197
Molecular diagnosis and monitoring of chronic myelogenous leukemia: BCR-Abl and more. 196
Algoplus®Scale in Older Patients with Dementia: A Reliable Real-World Pain Assessment Tool 196
Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes. possible relevance to the assays for the detection of micrometastatic breast cancer 195
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. 195
Monoclonal antibodies for non-Hodgkin's lymphoma: state of the art and perspectives. 193
Pathophysiological role of neutrophils in acute myocardial infarction. 192
Pegfilgrastim compared with filgrastim after autologous peripheral blood stem cell transplantation in patients with solid tumours and lymphomas. 192
Use of oral anticoagulant drugs in older patients with atrial fibrillation in internal medicine wards 191
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 191
Patient-tailored treatments with anti-EGFR monoclonal antibodies in advanced colorectal cancer: KRAS and beyond. 190
Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules 189
Treatment with KLEPTOSE® CRYSMEB reduces mouse atherogenesis by impacting on lipid profile and Th1 lymphocyte response 188
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition 187
Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors As Therapeutics: Rationales, Controversies, Clinical Experience. 186
Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments. Concordance with experimental results. 185
Peripheral blood vs. bone marrow for molecular monitoring of BCR-ABL1 levels in chronic myelogenous leukemia, a retrospective analysis in allogeneic bone marrow recipients. 185
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice. 185
Appropriateness of prescription of oral anticoagulant therapy in acutely hospitalized older people with atrial fibrillation. Secondary analysis of the SIM-AF cluster randomized clinical trial 185
Carvedilol Prevents Doxorubicin-induced Free Radical release and Oxidative Damage in Cardiomyocytes. 184
Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA 184
Evaluating treatment response of chronic myeloid leukemia: emerging science and technology. 182
Systems medicine in oncology: Signaling network modeling and new-generation decision-support systems 181
Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 180
Hedgehog Signaling Is Useful as a Novel Molecular Marker for Predicting Relapse and Resistance During Chronic Myeloid Leukemia Treatment 180
Appropriateness of oral anticoagulant therapy prescription and its associated factors in hospitalized older people with atrial fibrillation 180
Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols. 179
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 179
Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells. 178
Frailty assessment in elective gastrointestinal oncogeriatric surgery: Predictors of one-year mortality and functional status 178
Evaluation of prognostic indices in elderly hospitalized patients 177
The new small tyrosine-kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs 177
CD38-Induced Metabolic Dysfunction Primes Multiple Myeloma Cells for NAD+-Lowering Agents 176
NAD+ METABOLISM RESTRICTION BOOSTS HIGH-DOSE MELPHALAN EFFICACY IN PATIENTS WITH MULTIPLE MYELOMA 176
Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer 176
Activation of the death receptor apoptosis pathway by TRAIL overcomes anticancer drug resisitance in antiapoptotic bcl-2 family members expressing lymphoma cells 175
Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum. 174
Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer 173
Clinical characteristics, management and in-hospital mortality of patients with coronavirus disease 2019 in Genoa, Italy 172
Treatment with Angiotensin-(1-7) reduces inflammation in carotid atherosclerotic plaques. 171
Nicotinamide Phosphoribosyltransferase As A Target In Inflammation-Related Disorders. 171
Selectivity hot-spots of sirtuin catalytic cores 170
Dual NAMPT and BTK targeting leads to synergistic killing of Waldenström macroglobulinemia cells regardless of MYD88 and CXCR4 somatic mutation status 170
The effect of preoperative chemoradiotherapy on lymph nodes harvested in TME for rectal cancer. 169
Abstract CT075: Fasting-mimicking diet and hormone therapy modulates metabolic factors to promote breast cancer regression and reduce side effects 169
Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells 168
The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level 168
Role of genotype-based approach in the clinical management of adult acute myeloid leukemia with normal cytogenetics. 167
Proteasome inhibitor-induced apoptosis in human monocyte-derived dendritic cells. 167
Catastrophic NAD+ Depletion through Nampt Inhibition in Activated T Lymphocytes Reduces Demyelination and Disability in EAE. 167
Predictive values of two frailty screening tools in older patients with solid cancer: a comparison of SAOP2 and G8 166
Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status 165
The use of dendritic cells in cancer immunotherapy. 163
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 163
Immunotherapy with dendritic cells for cancer 162
Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis 161
Amino acid depletion triggered by L-asparaginase sensitizes MM cells to carfilzomib by inducing mitochondria ROS-mediated cell death 161
vitamin C, aging and Alzheimer's disease 160
NAD+ Levels Control Ca2+ Store Replenishment and Mitogen-induced Increase of Cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 Channel Gating in Human T Lymphocytes. 159
Evidence on the pathogenic role of auto-antibodies in acute cardiovascular diseases. 158
Aromatase inhibitor-induced bone loss osteosarcopenia in older patients with breast cancer: effects of the RANK/RANKL system’s inhibitor denosumab vs. bisphosphonates 157
Synthesis of Pyrrolidine 3,4-Diol Derivatives with Anticancer Activity on Pancreatic Tumor Cells 156
Totale 19.692
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Categoria #
all - tutte 116.678
article - articoli 111.086
book - libri 0
conference - conferenze 2.591
curatela - curatele 0
other - altro 0
patent - brevetti 2.100
selected - selezionate 0
volume - volumi 901
Totale 233.356
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.575 76 198 172 338 116 201 133 534 132 249 121 305
2022/20232.793 279 268 35 310 475 387 14 198 414 54 315 44
2023/20241.747 57 178 57 252 189 309 116 115 70 33 109 262
2024/20255.318 234 338 115 405 596 468 515 974 215 270 522 666
2025/202610.465 1.209 325 652 764 1.351 756 1.426 568 789 1.137 728 760
2026/2027897 897 0 0 0 0 0 0 0 0 0 0 0
Totale 36.231