IRIS
TONETTI, MICHELA
 Distribuzione geografica
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Continente #
EU - Europa 9.833
AS - Asia 33
SA - Sud America 17
Totale 9.883
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Nazione #
IT - Italia 9.832
CN - Cina 23
BR - Brasile 11
AR - Argentina 5
VN - Vietnam 5
SG - Singapore 3
CO - Colombia 1
ID - Indonesia 1
RU - Federazione Russa 1
SA - Arabia Saudita 1
Totale 9.883
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Città #
Genova 6.158
Genoa 2.164
Rapallo 819
Vado Ligure 675
Bordighera 11
Beijing 10
Rio de Janeiro 3
Hanoi 2
Ho Chi Minh City 2
Rome 2
Singapore 2
Bogotá 1
Curitiba 1
Feira de Santana 1
Goiânia 1
Jeddah 1
Lomas de Zamora 1
Makhachkala 1
Monte Grande 1
Pampa del Infierno 1
Paraibuna 1
Pontevedra 1
Poços de Caldas 1
Quatro Barras 1
Santo Tomé 1
Sorriso 1
Sumaré 1
Vinh 1
Totale 9.865
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Nome #
Differential role of NADP+ and NADPH in the activity and structure of GDP-D-mannose 4,6-dehydratase from two chlorella viruses 187
A novel dimeric fluoropyrimidine molecule behaves as a remote precursor of 5-Fluoro-2'-deoxyuridine in human erythrocytes. 175
The Autonomous Glycosylation of Large DNA Viruses 153
Effects of microRNAs on fucosyltransferase 8 (FUT8) expression in hepatocarcinoma cells 144
Chloroviruses have a sweet tooth 144
Core fucosylation of N-linked glycans in leukocytes adhesion deficiency/congenital disorder of glycosylation IIc fibroblasts 143
Identification of an L-rhamnose synthetic pathway in two nucleocytoplasmic large DNA viruses 142
Impairment of the Golgi GDP-L-fucose transport and unresponsiveness to fucose replacement therapy in LAD II patients 141
Differential role of NADP+ and NADPH in the activity and structure of GDP-D-mannose 4,6-dehydratase from two chlorella viruses 141
Fucose supplementation in LAD II 139
Enhanced antitumor activity of adriamycin by encapsulation in mouse erythrocytes targeted to liver and lungs. 136
Characterization of a UDP-N-acetylglucosamine biosynthetic pathway encoded by the giant DNA virus Mimivirus 136
Leukocyte adhesion deficiency (LAD) type II/carbohydrate deficient glycoprotein (CDG)IIc-founder effect and genotype/phenotype correlation 135
N-linked Glycans of Chloroviruses Sharing a Core Architecture without Precedent 134
Impairment of the Golgi GDP-L-fucose transport and unresponsiveness to fucose replacement therapy in LAD II patients 132
Encapsulation of doxorubicin in liver-targeted erythrocytes increases the therapeutic index of the drug in a murine metastatic model 132
Giant virus Megavirus chilensis encodes the biosynthetic pathway for uncommon acetamido sugars 131
Giant DNA Virus Mimivirus Encodes Pathway for Biosynthesis of Unusual Sugar 4-Amino-4,6-dideoxy-D-glucose (Viosamine). 131
Synergistic Cytotoxicity of Carboplatin and Divicine on Murine Erythroleukemic Cells 129
The rare sugar N-acetylated viosamine is a major component of Mimivirus fibers 126
The N-glycan structures of the antigenic variants of chlorovirus PBCV-1 major capsid protein help to identify the virus-encoded glycosyltransferases 124
Structure of N-linked oligosaccharides attached to chlorovirus PBCV-1 major capsid protein reveals unusual class of complex N-glycans 124
Synthesis of GDP-L-Fucose by the Human FX protein 123
Biophysical Approaches to Solve the Structures of the Complex Glycan Shield of Chloroviruses 123
Use of glutaraldehyde treated autologous human erythrocytes for hepatic targeting of doxorubicin. 122
Carbohydrates: Translation from sticky to sweet 122
Defective intracellular activity of GDP-D-mannose 4,6 dehydratase in leukocytes adhesion deficiency Type II (LAD II) syndrome. 121
Enhanced intracellular activation of carboplatin in hemoglobin-synthesizing versus undifferentiated erythroleukemic cells 120
Multiple small molecular weight guanine nucleotide-binding proteins in human erythrocyte membranes 119
Expression, Purification and Characterization of GDP-D-Mannose 4,6-Dehydratase from Escherichia Coli 118
Human Red Blood Cells (RBC) as Bioreactors for the Production and the Release of Fluoropyrimidine Drugs from Encapsulated Pro-Drugs 116
Leukocyte Adhesion Deficiency 116
Probing the catalytic mechanism of GDP-4-keto-6-deoxy-D-mannose epimerase/reductase by kinetic and crystallographic characterization of site specific mutants 115
Enhanced formation of reactive species from cis- diammine (1,1-cyclobutane-dicarboxylato) platinum (II) (Carboplatin) in the presence of oxygen free radicals 114
Paramecium bursaria Chlorella Virus 1 encodes two enzymes involved in the biosynthesis of GDP-L-fucose and GDP-D-rhamnose 114
Cloning and expression of two enzymes involved in the de novo synthesis of GDP-L-fucose in PBCV-1 112
Cloning and expression of the human NADP(H)-binding protein FX 111
Occurence in human cells of a metabolic pathway converting dTDP-D-glucose to 6-deoxyhexoses 108
Core fucosylation of N-linked glycans in Lad II Cdg IIc fibroblasts 105
Characterization of the residual fucose-containing glycoconjugates in LAD II/CDGS IIc cells 104
Engineered erythrocytes as carriers and bioreactors for biomedical research 103
Encapsulation of Glucose Oxidase in mouse erythrocytes :an experimental model of oxidant-induced cytotoxicity and a means for splenic targeting of carrier erythrocytes. 103
In vitro reconstruction of the complete metabolic pathway that converts GDP-D-mannose to GDP-L-fucose in bacterial cells. 102
Quartz dissolution by the sponge Chondrosia reniformis (Porifera, Demospongiae) 102
Kinetic and Crystallographic Analises Support a Sequential-ordered Bi Bi Catalytic Mechanism for Escherichia Coli Glucose-1-Thymidyltransferase. 101
Defective intracellular activity of GDP-D-mannose 4,6 dehydratase in leukocyte adhesion deficiency type II (LAD II) 100
Quaternary assembly and crystal structure of GDP-D-mannose 4,6 dehydratase from Paramencium bursaria Chlorella virus 99
Identification of the molecular basis of leukocytes adhesion deficiency Type II (LAD II) syndrome 97
Effect of defective import of GDP-fucose into Golgi apparatus on glycoconjugates composition in cells from LAD II patient 97
Preliminary structural characterization of recombinant GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from E.coli 94
Tissue Specific Transplantation Antigen P35B (= GDP-4-keto-6-D-Deoxymannose Epimerase-Reductase) (TSTA3) 94
In vivo liver and lung targeting of adriamycin encapsulated in glutaraldehyde-treated murine erythrocytes. 92
Differential terminal fucosylation of N-Linked glycans versus protein O-Fucosylation in Leukocyte Adhesion Deficiency Type II (CDG IIc) 91
The glycosyaltion in nucleo-cytoplasmic large DNA viruses (NVLDV) 91
Use of mass spectrometry to characterize the products of two enzymes encoded by Chlorella Virus PBCV-1 90
Time -dependent normalization of defective Slex expression and GDP-mannose 4,6 dehydratase (GMD) activity in long-term culture of lymphocytes from a LAD II patients. 89
The Chlorella virus PBCV-1 encodes two enzymes involved in the de novo synthesis of GDP-L-fucose and GDP-D-rhamnose 88
The high resolution structure of GDP-4-keto-6-deoxy-D-mannose epimerase/reductase. 88
GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from E. coli, a key enzyme in the biosynthesis of GDP-L-fucose displays the strucutral characteristics of the RED protein homology superfamily 88
Le comunità di pratica presso l’Università di Genova: l’esperienza e le motivazioni dei partecipanti 87
Extracellular ATP Potentiates Nitric Oxide Synthase Expression Induced by Lipopolysaccharide in Raw 264.7 Murine Macrophages 86
Engineered Erythrocytes as Biotechnological Tools for Advanced Therapies 86
Chlorovirus PBCV-1 protein A064R has three of the transferase activities necessary to synthesize its capsid protein N-linked glycans 86
Synthesis and characterization of a specific peptide nuclei acid that inhibits expression of inducible NO synthase 85
Primary structure,cDNA sequence and tissue localization of the human NADP-binding protein FX. 85
Engineered erythrocytes as carriers and bioreactors. 84
Unraveling the pathogenic bases of Catel-Manzke syndrome using a zebrafish knock-out model 83
The defect of the Golgi GDP-L-fucose transporter IIc:effect on GDP-L-fucose metabolism. 83
Chlorella Virus PBCV-1 encodes two enzymes involved in the biosynthesis of GDP-L-fucose and GDP-D-rhamnose 83
Structural and enzymatic characterization of human recombinant GDP-D-mannose 4,6 dehydratase 83
Differential terminal fucosylation of N-Linked glycans versus protein O-Fucosylation in Leukocyte Adhesion Deficiency Type II (CDG IIc) 83
Effects of the murine L929 and L1210 cell lines on nitric oxide and TNFalfa production by RAW 264.7 murine macrophages. 82
Human and Murine Erythrocytes as Bioreactors releasing the antineoplastic drug 5-fluoro-2'-deoxyuridine. 82
Core fucosylation of glycoprotein in LAD II/CDGs IIc fibroblasts 81
The NADP(H)-binding protein FX is an enzyme involved in the synthesis of GDP-L-fucose. 79
Identification of a metabolic pathway able to convert dTDP-D-glucose to 6-deoxyhexoses in human cells 79
Structural and enzymatic characterization of recombinant GDP-D-mannose dehydratase (GMD) from PBCV-1 virus. 78
Come avviare un programma di Faculty Development: l’esperienza dell’Università di Genova 78
Liver targeting of autologous erythrocytes loaded with doxorubicin 77
Structural and enzymatic characterization of recombinant GDP-D-mannose dehydratase (GMD) from PBCV-1 virus 76
Structural and enzymatic characterization of recombinant GDP-D-mannose dehydratase (GMD) from PBCV-1 virus 75
Differential terminal fucosylation of N-Linked glycans versus protein O-Fucosylation in Leukocyte Adhesion Deficiency Type II (CDG IIc). 75
The metabolism of 6-deoxhexoses in bacterial and animal cells 74
GDP-L-fucose metabolism in fibroblasts from LAD II/CDG IIc patients. 74
Analisi strutturale degli oligosaccaridi N-linked e O-linked contenenti fucoso nelle glicoproteine di pazienti affetti da sindrome LAD II 71
The chlorella virus PBCV-1 encodes two enzymes involved in the de novo synthesis of GDP-L-fucose. 70
Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced b indoleamine 2,3-dioxgenase 69
Relationship between elevated FX expression and increased production of GDP-L-fucose, a common donor substrate for fucosylation in human hepatocellular carcinoma and hepatoma cell lines. 68
Interaction of carboplatin with carrier human erythrocytes 68
Il corso di formazione all’innovazione didattica universitaria (FOR.I.U.) dell’Università di Genova 68
Structural and enzymatic characterization of recombinant GDP-D-mannose dehydratase (GMD) from PBCV-1 virus. 67
Extracellular ATP enhances mRNA levels of nitric oxide synthase and TNF-a in lipopolysaccharide-treated RAW 264.7 murine macrophage 65
Interactions of carboplatin with human erythrocytes and murine erythroleukemic cells. 65
Glucose 6-phosphate dehydrogenase from human erythrocytes: identification of N-acetil-alanine at the N-terminus of the mature protein 62
Effects of microRNAs on fucosyltransferase 8 expressio in hepatocarcinoma cells 61
Identification of cis-diamminedichloroplatinum adducts with DNA by HPLC and mass Spectrometry 57
The L-Rhamnose Biosynthetic Pathway in Trichomonas vaginalis: Identification and Characterization of UDP-D-Glucose 4,6-dehydratase 43
Expanding the Occurrence of Polysaccharides to the Viral World: The Case of Mimivirus 39
Unveiling the GT114 family: Structural characterization of A075L, a glycosyltransferase from Paramecium bursaria chlorella virus-1 (PBCV-1) 28
Generation of a tgds knock-out zebrafish model for the study of the developmental defects in Catel-Manzke Syndrome 19
Totale 9.915
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Categoria #
all - tutte 32.588
article - articoli 23.192
book - libri 0
conference - conferenze 6.821
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 2.575
Totale 65.176
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021332 0 0 0 0 48 34 31 38 52 60 32 37
2021/20221.111 30 87 84 132 41 54 78 273 29 96 41 166
2022/20231.013 117 54 10 99 175 191 0 85 182 4 84 12
2023/2024471 27 89 17 48 38 91 25 27 15 8 17 69
2024/20251.557 43 119 53 103 258 144 148 201 41 74 166 207
2025/2026700 344 67 98 174 17 0 0 0 0 0 0 0
Totale 9.967