IRIS
SPARATORE, BIANCA
 Distribuzione geografica
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Continente #
EU - Europa 15.018
AS - Asia 19
Totale 15.037
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Nazione #
IT - Italia 15.018
CN - Cina 19
Totale 15.037
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Città #
Genova 10.039
Genoa 2.790
Rapallo 1.248
Vado Ligure 929
Bordighera 12
Beijing 8
Totale 15.026
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Nome #
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 212
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 195
A vincristine-resistant murine erythroleukemia cell line secretes a differentiation enhancing factor. 183
A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation 169
Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment 169
Acyl-CoA-binding protein is a potent m-calpain activator 168
The calpain-calpastatin system in mammalian cells: properties and possible functions 165
Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase. 162
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 162
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain. 162
Activation by hemoglobin of the Ca2+-requiring neutral proteinase of human erythrocytes: structural requirements. 161
Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NK p30 157
Glucose 6-phosphate dehydrogenase activity in membranes of erythrocytes from normal individuals and subjects with Mediterranean G6PD deficiency. 154
Characterization of the calpastatin defect in erythrocytes from patients with essential hypertension. 152
Interactions of Zn2+ and Mg2+ with rabbit liver fructose 1,6 bisphosphatase. 151
Characterization of the defective calpain-endogenous calpain inhibitor system in erythrocytes from Milan hypertensive rats. 149
18β-Glycyrrhetic Acid Inhibits Immune Activation Triggered by HMGB1, a Pro-inflammatory Protein Found in the Tear Fluid during Conjunctivitis and Blepharitis. 148
On the mechanism of inhibition of fructose 1,6-bisphosphatase by fructose 2,6-bisphosphate. 147
The role of calpain in the selective increased phosphorylation of the anion-transport protein in red cell of hypertensive subjects. 146
Changes during fasting in the activity of a specific lysosomal proteinase, fructose-1,6-bisphosphatase converting enzyme. 146
Cathepsin M: a lysosomal proteinase with aldolase-inactivating activity 145
Activation of NADPH oxidase and phosphorylation of membrane proteins in human neutrophils: coordinate inhibition by a surface antigen-directed monoclonal antibody. 145
Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process. 145
A dual role for the Ca2+-requiring proteinase in the degradation of hemoglobin by erythrocyte membrane proteinases. 143
Binding of Zn2+ to rabbit muscle fructose 1,6-bisphosphatase and its effect on the catalytic properties. 143
Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase. 143
The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes 141
Cytosolic calcium dependent proteinase of human erythrocytes: formation of an enzyme-natural inhibitor complex induced by Ca2+ ions. 140
Inactivation of liver aldolase in fasting rabbits: evidence for the accumulation of two different immunoreactive forms. 140
Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli 140
The plasma membrane calcium pump is the preferred calpain substrate within the erythrocyte 138
Characterization of the inactive form of fructose-1,6-bisphosphate aldolase isolated from livers of fasted rabbits. 138
Two cytosolic, Ca2+-dependent, neutral proteinases from rabbit liver: purification and properties of the proenzymes. 138
NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy? 136
Phosphorylation and proteolytic modification of specific cytoskeletal proteins in human neutrophils stimulated by phorbol 12-myristate 13-acetate. 135
Selective Pro-Inflammatory Activation of Astrocytes by High Mobility Group Box 1 Protein Signaling 134
The calpastatin defect in hypertension is possibly due to a specific degradation by calpain. 134
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein. 134
Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation 133
Inactivation of fructose 1,6-bisphosphatase by a lysosomal proteinase is reversed by cystamine. 132
Decreased level of calpain inhibitor activity in kidney from Milan hypertensive rats. 131
Stimulation of erythroleukaemia cell differentiation by extracellular high mobility group-box protein 1 is independent of receptor for advanced glycation end products. 130
Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation. 130
High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo. 129
Antisense oligodeoxynucleotide inhibition of delta protein kinase C expression accelerates induced differentiation of murine erythroleukaemia cells 129
Isolation and characterization of calpain activator protein from bovine brain. 129
Modulation of the intracellular Ca2+-dependent proteolytic system is critically correlated with the kinetics of differentiation of murine erythroleukemia cells 127
Changes in activity of fructose-1,6-bisphosphate aldolase in livers of fasted rabbits and accumulation of crossreacting immune material. 127
Endogenous inhibitors of lysosomal proteinases 127
The breakpoint identified in a balanced de novo translocation t(7;9)(p14.1;q31.3) disrupts the A-kinase (PRKA) anchor protein 2 gene (AKAP2) on chromosome 9 in a patient with Kallmann syndrome and bone anomalies 126
Binding of monoclonal antibody to cathepsin M located on the external surface of rabbit lysosomes. 126
Biochemical responses in activated human neutrophils mediated by protein kinase C and a Ca2+-requiring proteinase. 126
Functional role of the charge at the T538 residue in the control of protein kinase Ctheta 125
Stimulated astrocytes release high-mobility group 1 protein, an inducer of LAN-5 neuroblastoma cell differentiation 125
Comparative patterns of 'in vitro' oxidative hemolysis of normal and glucose 6-phosphate dehydrogenase (G6PD)-deficient erythrocytes. 125
In vitro correction of erythrocyte glucose 6-phosphate dehydrogenase (G6PD) deficiency. 125
Selective proinflammatory activation of astrocytes by high mobility group box 1 protein signaling 124
Introduction of beta isozyme of protein kinase C accelerates induced differentiation of murine erythroleukemia cells 123
Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein 123
Regulation of the Ca2+-dependent neutral proteinases from rabbit liver by an endogenous inhibitor. 122
Characterization of the biological role of murine erythroleukemia cells "differentiation enhancing factor" using antisense oligodeoxynucleotides. Biochem. Biophys. Res. Commun. 193, 941-947 121
Differentiation of murine erythroleukemia cells by hexamethylenebisacetamide involves secretion and binding to membranes of a differentiation enhancing factor. 121
Limited proteolysis of liver aldolase and fructose 1,6-bisphosphatase by lysosomal proteinases: effect on complex formation. 120
Differentiation of HL60 promyelocytic cells is promoted by a "differentiation enhancing factor" produced by erythroleukemia cells" 118
Human neuroblastoma cell differentiation requires protein kinase C-θ 118
Role of phospholipids in the activation of the Ca2+-dependent neutral proteinase of human erythrocytes. 118
Localization of two lysosomal proteinases on the external surface of the lysosomal membrane. 118
Proteolysis of human reticulocyte membrane proteins: evidence for a physiological role of the acid endopeptidases. 117
Interaction of rabbit liver cathepsin M and fructose 1,6-bisphosphatase converting enzyme with their endogenous inhibitors. 117
Decay of proteinase and peptidase activities of human and rabbit erythrocytes during cellular aging. 117
ATP induces the release of a neutral serine proteinase and enhances the production of superoxide anion in membranes from phorbol ester-activated neutrophils. 116
Mechanism of action of a new component of the ca2+dependent proteolytic system in rat brain:the calpain activator 115
Characterization of three rabbit liver lysosomal proteinases with fructose 1,6-bisphosphatase converting enzyme activity. 115
An endogenous activator of the Ca2+-dependent proteinase of human neutrophils that increases its affinity for Ca2+. 115
Bioactive molecules isolated from olive pomace extract protect cells from calcium mediated damages 114
Cytolytic effects of neutrophils: role for a membrane-bound neutral proteinase. 112
Characterization of the single peptide generated from the amino-terminus end of alpha- and beta-hemoglobin chains by the Ca2+-dependent neutral proteinase. 111
Cytosolic calcium dependent neutral proteinase of human erythrocytes: the role of calcium ions on the molecular and catalytic properties of the enzyme. 110
Modulation of inhibitory efficiency of rat skeletal muscle calpastatin by phosphorylation. 110
Identification of proteolytic activities in the cytosolic compartment of mature human erythrocytes. 110
A 6 kda protein homologous to the N-terminus of the HMG1 protein promoting stimulation of murine erytrolekemia cell differentiation. 110
Decreased level of calpain inhibitor activity in red blood cells from Milan hypertensive rats. 109
Phosphorylation of proteins in human neutrophils activated with phorbol myristate acetate or with chemotactic factor. 109
Differences and similarities among three acidic endopeptidases associated with human erythrocyte membranes. Molecular and functional studies. 109
Evidence for an interaction between fructose 1,6-bisphosphatase and fructose 1,6-bisphosphate aldolase. 108
Erythrocyte deficiency in calpain inhibitor activity in essential hypertension. 108
A Novel signalling mechanism promoting Ca(2+) driven cell responses through high-mobility group box-1/NMDA receptor interaction. 108
Properties of calpastatin forms in rat brain 107
Cytosolic Ca2+-dependent neutral proteinases from rabbit liver: activation of the proenzymes by Ca2+ and substrate. 107
Role of δ-pkc on the differentiation process of murine erythroleukemia cells 106
Identification of an endogenous activator of calpain in rat skeletal muscle. 105
The reversible activation by Mn2+ ions of the Ca2+-requiring neutral proteinase of human erythrocytes. 104
Phosphorylation by protein kinase C of a 20-kDa cytoskeletal polypeptide enhances its susceptibility to digestion by calpain. 103
Neuronal differentiation of PC12 cells involves changes in protein kinase C-θ distribution and molecular properties. Biochem. Biophys. Res. Commun. 275, 149-153 101
Effects of a monoclonal anti-calpain antibody on responses of stimulated human neutrophils. Evidence for a role for proteolytically modified protein kinase C. 101
Cutting edge: extracellular high mobility proup box-1 protein s a proangiogenic cytokine 101
Following association to the membrane, human erythrocyte procalpain is converted and released as fully active calpain. 101
Participation of protein kinase C in the activation of human neutrophils by phorbol ester 100
The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol myristic acid. 99
Enhanced activation of the respiratory burst oxidase in neutrophils from hypertensive patients. 98
Totale 12.971
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Categoria #
all - tutte 43.660
article - articoli 41.032
book - libri 493
conference - conferenze 1.200
curatela - curatele 0
other - altro 0
patent - brevetti 309
selected - selezionate 0
volume - volumi 626
Totale 87.320
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021632 0 0 0 53 48 91 43 66 78 96 83 74
2021/20221.421 36 92 65 198 49 123 117 282 64 153 58 184
2022/20231.472 135 81 8 192 244 298 1 93 276 10 122 12
2023/2024613 34 86 5 64 86 142 22 28 37 6 33 70
2024/20252.095 100 163 71 134 342 219 127 286 44 83 232 294
2025/2026818 415 77 148 178 0 0 0 0 0 0 0 0
Totale 15.123