IRIS
VILLA, VALENTINA
 Distribuzione geografica
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Continente #
EU - Europa 6.918
AS - Asia 629
NA - Nord America 285
SA - Sud America 74
AF - Africa 12
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 7.922
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Nazione #
IT - Italia 6.824
US - Stati Uniti d'America 268
SG - Singapore 265
CN - Cina 170
VN - Vietnam 119
FR - Francia 45
BR - Brasile 44
HK - Hong Kong 28
DE - Germania 18
MX - Messico 9
JP - Giappone 8
AR - Argentina 7
EC - Ecuador 7
ID - Indonesia 6
CH - Svizzera 5
CO - Colombia 5
IN - India 5
IQ - Iraq 5
ZA - Sudafrica 5
BD - Bangladesh 4
BO - Bolivia 4
GB - Regno Unito 4
PH - Filippine 4
CA - Canada 3
CL - Cile 3
PL - Polonia 3
TR - Turchia 3
UA - Ucraina 3
VE - Venezuela 3
AU - Australia 2
DK - Danimarca 2
FI - Finlandia 2
HN - Honduras 2
IE - Irlanda 2
KE - Kenya 2
NL - Olanda 2
NP - Nepal 2
PK - Pakistan 2
RO - Romania 2
SY - Repubblica araba siriana 2
AL - Albania 1
BE - Belgio 1
BG - Bulgaria 1
BZ - Belize 1
CY - Cipro 1
DZ - Algeria 1
GA - Gabon 1
JM - Giamaica 1
JO - Giordania 1
KR - Corea 1
KZ - Kazakistan 1
LK - Sri Lanka 1
LT - Lituania 1
MA - Marocco 1
NC - Nuova Caledonia 1
RU - Federazione Russa 1
SI - Slovenia 1
TG - Togo 1
TH - Thailandia 1
TN - Tunisia 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 7.922
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Città #
Genova 3.952
Genoa 1.785
Rapallo 554
Vado Ligure 501
Singapore 121
San Jose 114
Lauterbourg 45
Ho Chi Minh City 37
Ashburn 33
Hong Kong 27
Beijing 20
Bordighera 19
Hanoi 18
New York 18
Frankfurt am Main 16
Santa Clara 12
Tokyo 8
Da Nang 7
Chicago 5
Council Bluffs 5
Los Angeles 5
Zurich 5
Mexico City 4
Quito 4
São Paulo 4
Tianjin 4
Haiphong 3
Hải Dương 3
Johannesburg 3
La Paz 3
Shanghai 3
Amsterdam 2
Berazategui 2
Biên Hòa 2
Brasília 2
Chennai 2
Copenhagen 2
Dublin 2
Guangzhou 2
Helsinki 2
Jakarta 2
Kyiv 2
Medellín 2
Milan 2
Nairobi 2
Nanjing 2
Nha Trang 2
Ninh Bình 2
Orem 2
Rio de Janeiro 2
Rome 2
Santiago 2
Verona 2
Warsaw 2
Agrolândia 1
Algiers 1
Amman 1
Araranguá 1
Araucária 1
Arraias 1
Atlanta 1
Babahoyo 1
Baghdad 1
Bangkok 1
Barcelona 1
Basingstoke 1
Belize City 1
Belleville 1
Boa Vista 1
Bornova 1
Brisbane 1
Brussels 1
Bucharest 1
Buffalo 1
Bulungan 1
Bắc Giang 1
Bắc Ninh 1
Caloocan City 1
Camaçari 1
Camposampiero 1
Can Tho 1
Canguçu 1
Cao Lanh 1
Caracas 1
Carapicuíba 1
Cardiff 1
Cebu City 1
Charleston 1
Charlotte 1
Chengdu 1
City of London 1
Cochabamba 1
Couva 1
Curitiba 1
Cúcuta 1
Da Lat 1
Dallas 1
Damascus 1
Des Moines 1
Diamantina 1
Totale 7.430
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Nome #
Characterization of the pro-apoptotic intracellular mechanisms induced by a toxic conformer of the recombinant human prion protein fragment 90-231 248
Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells 242
Amyloid precursor protein modulates ERK1/2 signaling 241
Calcium binding promotes Prion Protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure 231
Peptide Receptor Targeting in Cancer: The Somatostatin Paradigm 220
Apoptotic cell death and impairment of L-type voltage sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126 215
Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis 214
Dual modulation of ERK1/2 and p38 MAP kinase activities induced by minocycline reverses the neurotoxic effects of the prion protein fragment 90-231 210
Amino-terminally truncated prion protein PrP90-231 induces microglial activation in vitro 204
Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells 198
Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death 196
Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90–231 Neurotoxic Effects in Cerebellar Granule Neurons 193
Different structural stability and toxicity of PrPARR and PrPARQ sheep prion protein variants 182
Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic 181
Canine osteosarcoma cell lines contain stem-like cancer cells: Biological and pharmacological characterization 180
Emerging targets in pituitary adenomas: role of the CXCL12/CXCR4-R7 system 179
Novel celecoxib analogues inhibit glial production of prostaglandinE2, nitric oxide, and oxygen radicals reverting the neuroinflammatoryresponses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide 178
ACTIVATION OF AUTOPHAGY PATHWAY AS NEUROPROTECTIVE MECHANISM AGAINST AMYLOIDOGENIC PRION PEPTIDE 174
The chemokine SDF1/CXCL12: a novel autocrine/paracrine factor involved in pituitary adenoma development 173
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction 173
Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment 170
ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation 166
Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231 166
The phosphotyrosine phosphatase PTPh mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2 159
Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation 158
Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity 157
Role of prion protein aggregation in neurotoxicity 153
Celecoxib, a COX-2 inhibitor, blocks microglial activation induced by a neurotoxic conformer of hPrP90-231 153
Addressing thermal and mechanical stability of human prion protein with single molecule and ensemble measurements 153
Psychological treatments and psychotherapies in the neurorehabilitation of pain: Evidences and recommendations from the italian consensus conference on pain in neurorehabilitation 152
p38 MAP Kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells 151
Aminoterminally truncated human Prion protein fragment 90-231 forms intracellular aggregates and causes lysosomal loss of impermeability 150
Expression in E. coli and purification of recombinant fragments of wild type and mutant human prion protein 149
High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein 147
Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity 145
Molecular mechanisms involved in the aggregation and fibril formation of the recombinant human prion fragment PrP90-231 129
Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor 3 (SSTR3) mediated regulation of endothelial NOS and MAP kinase activities” 124
Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling 123
Intracellular accumulation of a mild-denatured monomer of the human PrP fragment 90-231 (hPrP90-231), as possible mechanism of its neurotoxic effects 122
Prion protein fragment 90-231 induces microglia activation: role of ERK1/2 and p38 MAP kinases in nitric oxide production and CCL5 secretion 121
Nitric oxide production stimulated by the basic fibroblast growth factor requires the synthesis of ceramide 121
Study of the Molecular Mechanism Responsible of the Conformational Changes Induced by E200K and D202N Pathological PrP Mutation 113
Expression of somatostatin receptors mRNA in human meningiomas and their implication in in vitro antiproliferative activity 110
Molecular mechanisms mediating the neuroprotective effects of quinacrine and minocycline on cell death induced by the prion protein fragment 90-231 (hPrP90-231) 107
Study of the molecular mechanisms responsible of the transition of the prion protein fragment 90-231 in a neurotoxic conformation. 106
Somatostatinergic control of Kaposi’s sarcoma growth through the inhibition of angiogenesis 96
Neurotoxicity of the recombinant prion protein fragment 90-231 in SH-SY5Y cells is dependent on its conversion in beta-structured-isoform 89
Somatostatin receptor expression in patients with stromal tumors of the gastrointestinal tract 87
Somatostatin receptor expression in stromal tumors of the gastrointestinal 84
Characterization of the intracellular mechanisms mediating somatostatin and lanreotide inhibition of DNA synthesis and growth hormone release from dispersed human GH-secreting pituitary adenoma cells in vitro 80
The activation of the phosphotyrosine phosphatase eta is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation 65
Totale 8.038
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Categoria #
all - tutte 23.541
article - articoli 21.932
book - libri 0
conference - conferenze 1.272
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 337
Totale 47.082
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202148 0 0 0 0 0 0 0 0 0 0 22 26
2021/2022672 16 75 35 68 20 52 61 149 20 54 32 90
2022/2023648 48 43 5 64 110 116 1 54 94 5 101 7
2023/2024346 22 33 7 48 22 87 28 20 17 6 24 32
2024/20251.197 32 68 30 117 165 123 92 232 39 44 122 133
2025/20261.780 243 51 252 184 244 141 265 91 106 198 5 0
Totale 8.038