IRIS
VILLA, VALENTINA
 Distribuzione geografica
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Continente #
EU - Europa 6.950
AS - Asia 688
NA - Nord America 601
Continente sconosciuto - Info sul continente non disponibili 117
SA - Sud America 82
AF - Africa 14
OC - Oceania 3
Totale 8.455
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Nazione #
IT - Italia 6.848
US - Stati Uniti d'America 561
SG - Singapore 267
CN - Cina 176
VN - Vietnam 123
BD - Bangladesh 47
BR - Brasile 47
FR - Francia 46
HK - Hong Kong 29
DE - Germania 18
CA - Canada 13
MX - Messico 10
AR - Argentina 9
JP - Giappone 9
EC - Ecuador 8
CO - Colombia 7
ID - Indonesia 7
CH - Svizzera 5
GB - Regno Unito 5
IN - India 5
IQ - Iraq 5
ZA - Sudafrica 5
BO - Bolivia 4
PH - Filippine 4
CL - Cile 3
HN - Honduras 3
JM - Giamaica 3
NL - Olanda 3
PL - Polonia 3
RO - Romania 3
TR - Turchia 3
UA - Ucraina 3
VE - Venezuela 3
AU - Australia 2
CR - Costa Rica 2
CY - Cipro 2
DK - Danimarca 2
FI - Finlandia 2
GT - Guatemala 2
IE - Irlanda 2
KE - Kenya 2
NP - Nepal 2
PK - Pakistan 2
PR - Porto Rico 2
PT - Portogallo 2
SC - Seychelles 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
AL - Albania 1
BE - Belgio 1
BG - Bulgaria 1
BS - Bahamas 1
BZ - Belize 1
DZ - Algeria 1
ES - Italia 1
GA - Gabon 1
JO - Giordania 1
KR - Corea 1
KY - Cayman, isole 1
KZ - Kazakistan 1
LK - Sri Lanka 1
LT - Lituania 1
MA - Marocco 1
NC - Nuova Caledonia 1
RS - Serbia 1
RU - Federazione Russa 1
SI - Slovenia 1
TG - Togo 1
TH - Thailandia 1
TN - Tunisia 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 8.339
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Città #
Genova 3.952
Genoa 1.788
Rapallo 554
Vado Ligure 501
San Jose 136
Singapore 123
Ashburn 55
Lauterbourg 45
Ho Chi Minh City 37
Hong Kong 27
Beijing 26
Hanoi 21
New York 21
Bordighera 19
Frankfurt am Main 16
Santa Clara 13
Chicago 12
Los Angeles 9
Tokyo 9
Da Nang 7
Rome 6
Brooklyn 5
Council Bluffs 5
Mexico City 5
Zurich 5
Louisville 4
Milan 4
Nashville 4
Quito 4
São Paulo 4
Tianjin 4
Atlanta 3
Haiphong 3
Hải Dương 3
Johannesburg 3
La Paz 3
Medellín 3
Miami 3
Pittsburgh 3
Savannah 3
Shanghai 3
Tampa 3
Toms River 3
Warsaw 3
Akron 2
Amsterdam 2
Azusa 2
Berazategui 2
Biên Hòa 2
Brasília 2
Buffalo 2
Chennai 2
Clanton 2
Columbus 2
Copenhagen 2
Dallas 2
Detroit 2
Dublin 2
Fresno 2
Golden 2
Guangzhou 2
Guatemala City 2
Helsinki 2
Jakarta 2
Kyiv 2
Lawrenceville 2
Long Beach 2
Mount Airy 2
Nairobi 2
Nanjing 2
Naples 2
Nha Trang 2
Nicosia 2
Ninh Bình 2
Norristown 2
Orem 2
Phoenix 2
Plymouth 2
Princeton 2
Rio Rancho 2
Rio de Janeiro 2
San Antonio 2
San Diego 2
San José 2
Santiago 2
Sumter 2
Tegucigalpa 2
Verona 2
Virginia Beach 2
Waterbury 2
Agrolândia 1
Albacete 1
Algiers 1
Alpharetta 1
Alsip 1
Amman 1
Ancaster 1
Araranguá 1
Araucária 1
Arraias 1
Totale 7.562
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Nome #
Characterization of the pro-apoptotic intracellular mechanisms induced by a toxic conformer of the recombinant human prion protein fragment 90-231 265
Amyloid precursor protein modulates ERK1/2 signaling 259
Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells 257
Calcium binding promotes Prion Protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure 238
Peptide Receptor Targeting in Cancer: The Somatostatin Paradigm 226
Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis 224
Amino-terminally truncated prion protein PrP90-231 induces microglial activation in vitro 223
Apoptotic cell death and impairment of L-type voltage sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126 222
Dual modulation of ERK1/2 and p38 MAP kinase activities induced by minocycline reverses the neurotoxic effects of the prion protein fragment 90-231 217
Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells 205
Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death 205
Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90–231 Neurotoxic Effects in Cerebellar Granule Neurons 199
Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic 195
Different structural stability and toxicity of PrPARR and PrPARQ sheep prion protein variants 194
Canine osteosarcoma cell lines contain stem-like cancer cells: Biological and pharmacological characterization 186
Emerging targets in pituitary adenomas: role of the CXCL12/CXCR4-R7 system 185
ACTIVATION OF AUTOPHAGY PATHWAY AS NEUROPROTECTIVE MECHANISM AGAINST AMYLOIDOGENIC PRION PEPTIDE 184
ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation 182
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction 180
Novel celecoxib analogues inhibit glial production of prostaglandinE2, nitric oxide, and oxygen radicals reverting the neuroinflammatoryresponses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide 180
The chemokine SDF1/CXCL12: a novel autocrine/paracrine factor involved in pituitary adenoma development 177
Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231 177
Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment 177
The phosphotyrosine phosphatase PTPh mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2 172
Addressing thermal and mechanical stability of human prion protein with single molecule and ensemble measurements 169
Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation 164
Celecoxib, a COX-2 inhibitor, blocks microglial activation induced by a neurotoxic conformer of hPrP90-231 163
Psychological treatments and psychotherapies in the neurorehabilitation of pain: Evidences and recommendations from the italian consensus conference on pain in neurorehabilitation 163
Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity 162
Aminoterminally truncated human Prion protein fragment 90-231 forms intracellular aggregates and causes lysosomal loss of impermeability 160
p38 MAP Kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells 157
Role of prion protein aggregation in neurotoxicity 156
Expression in E. coli and purification of recombinant fragments of wild type and mutant human prion protein 156
High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein 151
Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity 149
Molecular mechanisms involved in the aggregation and fibril formation of the recombinant human prion fragment PrP90-231 136
Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor 3 (SSTR3) mediated regulation of endothelial NOS and MAP kinase activities” 127
Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling 127
Intracellular accumulation of a mild-denatured monomer of the human PrP fragment 90-231 (hPrP90-231), as possible mechanism of its neurotoxic effects 126
Prion protein fragment 90-231 induces microglia activation: role of ERK1/2 and p38 MAP kinases in nitric oxide production and CCL5 secretion 126
Nitric oxide production stimulated by the basic fibroblast growth factor requires the synthesis of ceramide 124
Study of the Molecular Mechanism Responsible of the Conformational Changes Induced by E200K and D202N Pathological PrP Mutation 118
Expression of somatostatin receptors mRNA in human meningiomas and their implication in in vitro antiproliferative activity 118
Molecular mechanisms mediating the neuroprotective effects of quinacrine and minocycline on cell death induced by the prion protein fragment 90-231 (hPrP90-231) 114
Study of the molecular mechanisms responsible of the transition of the prion protein fragment 90-231 in a neurotoxic conformation. 113
Somatostatinergic control of Kaposi’s sarcoma growth through the inhibition of angiogenesis 103
Somatostatin receptor expression in stromal tumors of the gastrointestinal 97
Neurotoxicity of the recombinant prion protein fragment 90-231 in SH-SY5Y cells is dependent on its conversion in beta-structured-isoform 95
Characterization of the intracellular mechanisms mediating somatostatin and lanreotide inhibition of DNA synthesis and growth hormone release from dispersed human GH-secreting pituitary adenoma cells in vitro 93
Somatostatin receptor expression in patients with stromal tumors of the gastrointestinal tract 89
The activation of the phosphotyrosine phosphatase eta is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation 70
Totale 8.455
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Categoria #
all - tutte 25.666
article - articoli 23.928
book - libri 0
conference - conferenze 1.361
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 377
Totale 51.332
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022672 16 75 35 68 20 52 61 149 20 54 32 90
2022/2023648 48 43 5 64 110 116 1 54 94 5 101 7
2023/2024346 22 33 7 48 22 87 28 20 17 6 24 32
2024/20251.197 32 68 30 117 165 123 92 232 39 44 122 133
2025/20261.942 243 51 252 184 244 141 265 91 106 198 99 68
2026/2027255 255 0 0 0 0 0 0 0 0 0 0 0
Totale 8.455