IRIS
PIETRA, GABRIELLA
 Distribuzione geografica
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Continente #
EU - Europa 10.815
NA - Nord America 1.160
AS - Asia 1.145
Continente sconosciuto - Info sul continente non disponibili 185
SA - Sud America 104
AF - Africa 21
OC - Oceania 2
Totale 13.432
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Nazione #
IT - Italia 10.605
US - Stati Uniti d'America 1.087
SG - Singapore 471
CN - Cina 313
VN - Vietnam 209
FR - Francia 80
BD - Bangladesh 61
BR - Brasile 56
FI - Finlandia 40
HK - Hong Kong 32
DE - Germania 26
CA - Canada 22
AR - Argentina 18
GB - Regno Unito 17
JP - Giappone 17
MX - Messico 11
CO - Colombia 10
JM - Giamaica 10
CH - Svizzera 9
CR - Costa Rica 9
EC - Ecuador 8
IN - India 8
ZA - Sudafrica 8
HN - Honduras 7
IQ - Iraq 7
RU - Federazione Russa 7
GT - Guatemala 6
PL - Polonia 5
NL - Olanda 4
TR - Turchia 4
VE - Venezuela 4
BB - Barbados 3
ES - Italia 3
PH - Filippine 3
UA - Ucraina 3
AE - Emirati Arabi Uniti 2
AO - Angola 2
AT - Austria 2
CI - Costa d'Avorio 2
CL - Cile 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
GY - Guiana 2
IL - Israele 2
MA - Marocco 2
NP - Nepal 2
PR - Porto Rico 2
PY - Paraguay 2
SA - Arabia Saudita 2
SE - Svezia 2
SI - Slovenia 2
UZ - Uzbekistan 2
AU - Australia 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
CG - Congo 1
EG - Egitto 1
ET - Etiopia 1
GU - Guam 1
HU - Ungheria 1
ID - Indonesia 1
IE - Irlanda 1
IR - Iran 1
JO - Giordania 1
LB - Libano 1
LV - Lettonia 1
MD - Moldavia 1
ME - Montenegro 1
MK - Macedonia 1
MN - Mongolia 1
MY - Malesia 1
NG - Nigeria 1
NO - Norvegia 1
OM - Oman 1
PE - Perù 1
PS - Palestinian Territory 1
RS - Serbia 1
SC - Seychelles 1
SV - El Salvador 1
TH - Thailandia 1
TW - Taiwan 1
UY - Uruguay 1
Totale 13.247
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Città #
Genova 6.456
Genoa 2.459
Vado Ligure 811
Rapallo 760
San Jose 277
Singapore 215
Ashburn 136
Lauterbourg 76
Ho Chi Minh City 50
Council Bluffs 45
Hanoi 45
Beijing 41
Helsinki 40
New York 34
Hong Kong 32
Santa Clara 22
Frankfurt am Main 21
Los Angeles 19
Milan 18
Tokyo 16
Da Nang 13
Buffalo 12
Dallas 10
Rome 10
Tianjin 10
Houston 9
Zurich 9
Haiphong 8
Las Vegas 8
Mexico City 8
Brooklyn 7
Chicago 7
Des Moines 6
Florence 6
Hải Dương 6
Philadelphia 6
Phoenix 6
Queens 6
San José 6
Bordighera 5
Jacksonville 5
Johannesburg 5
London 5
Montreal 5
Naples 5
St Louis 5
São Paulo 5
Washington 5
Biên Hòa 4
City of London 4
Guatemala City 4
Kingston 4
Nuremberg 4
Princeton 4
Quảng Ngãi 4
Alexandria 3
Amsterdam 3
Atlanta 3
Baghdad 3
Bogotá 3
Boydton 3
Charlotte 3
Janesville 3
Kansas City 3
Lafayette 3
Miami 3
Newark 3
Orem 3
Orlando 3
Paris 3
Pasadena 3
Phủ Lý 3
Pisa 3
Pittsburgh 3
Quito 3
Reading 3
Rochester 3
San Pedro Sula 3
Savannah 3
Spartanburg 3
Toronto 3
Turin 3
Abidjan 2
Anderson 2
Baldwin Park 2
Baltimore 2
Bergamo 2
Blythewood 2
Bologna 2
Brasília 2
Bridgetown 2
Bắc Ninh 2
Calexico 2
Campinas 2
Can Tho 2
Catania 2
Chennai 2
Cincinnati 2
Cleveland 2
Dearborn Heights 2
Totale 11.916
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Nome #
Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function 269
Identification of cytomegalovirus (CMV)-specific T lymphocytes displaying an effector-memory phenotype that kill CMV-infected target cells in an HLA-E-restricted fashion 262
Cytokines can counteract the inhibitory effect of MEK-i on NK-cell function 221
NK-cell editing mediates epithelial-to-mesenchymal transition via phenotypic and proteomic changes in melanoma cell lines 216
Human natural killer cells: news in the therapy of solid tumors and high-risk leukemias 213
Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment 202
Chronic lymphocytic leukemia nurse-like cells express hepatocyte growth factor receptor (c-MET) and indoleamine 2,3-dioxygenase and display features of immunosuppressive type 2 skewed macrophages 201
Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK cell function 196
Effect of tumor cells and tumor microenvironment on NK-cell function. 196
Detection of MAGE-1, -2, and -3 messenger RNA in tissue samples derived from lung and mammary tumors. 187
Human NK Cells: From Surface Receptors to the Therapy of Leukemias and Solid Tumors. 186
Targeting Syndecan-1, a molecule implicated in the process of vasculogenic mimicry, enhances the therapeutic efficacy of the L19-IL2 immunocytokine in human melanoma xenografts 185
Detection of oligoclonal T lymphocytes in lymph nodes draining from advanced non-small-cell lung cancer. 183
Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition 182
Adherent neoplastic cells grown at confluence downregulate HLA class I expression and enhance their susceptibility to lysis mediated by natural killer cells. 178
Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor 175
HO-1 downregulation favors BRAFV600 melanoma cell death induced by Vemurafenib/PLX4032 and increases NK recognition 174
alpha-Interferon treatment induces quantitative modifications of HLA class I-associated peptides eluted from cultured cancer cell lines 173
Intensified chemotherapy supported by DMSO-free peripheral blood progenitor cells in breast cancer patients. 168
Comparative analysis of NK- or NK-CTL-mediated lysis of immature or mature autologous dendritic cells 163
Analysis of the proliferative and phenotypic properties of tumor infiltrating lymphocytes expanded in vitro in the course of the clinical trial of adoptive immunotherapy of metastatic melanoma. 162
Influence of Vitamin D in Advanced Non-Small Cell Lung Cancer Patients Treated with Nivolumab 160
A new mechanism of resistance to NK cell attack in melanoma 159
A conserved energetic footprint underpins recognition of Human Leukocyte Antigen-E by two distinct αβ T cell receptors 157
HLA-E-restricted recognition of cytomegalovirus-derived peptides by human CD8+ cytolytic T lymphocytes. 155
Infusion of in vitro expanded tumour-infiltrating lymphocytes and recombinant interleukin-2 in patients with surgically resected lymph node metastases of malignant melanoma: a pilot study. 153
Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells 153
Human natural killer cells and other innate lymphoid cells in cancer: Friends or foes? 152
The emerging role of HLA-E-restricted CD8+ T lymphocytes in the adaptive immune response to pathogens and tumors. 150
Effect of Melanoma-derived Fibroblasts on NK Cell Phenotype and Functions 148
L19-IL2 immunocytokine in combination with the anti-syndecan-1 46F2SIP antibody format: A new targeted treatment approach in an ovarian carcinoma model 148
Structural basis for a major histocompatibility complex class Ib-restricted T cell response 147
Role of major histocompatibility complex class I expression and natural killer-like T cells in the genetic control of endometriosis. 147
Hypoxia modifies the transcriptome of human NK cells, modulates their immunoregulatory profile, and influences NK cell subset migration 147
Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation 147
Association Between Response to Nivolumab Treatment and Peripheral Blood Lymphocyte Subsets in Patients With Non-small Cell Lung Cancer 147
Natural killer cells lyse autologous herpes simplex virus infected targets using cytolytic mechanisms distributed clonotypically. 144
HLA-E-restricted recognition of human cytomegalovirus by a subset of cytolytic T lymphocytes 144
Purification and HPLC-MS analysis of a naturally processed HCMV-derived peptide isolated from the HEK-293T/HLA-E+/Ul40+ cell transfectants and presented at the cell surface in the context of HLA-E 144
Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines 143
How melanoma cells inactivate NK cells 142
Role of NK cells in immunotherapy and virotherapy of solid tumors 142
Hypoxia downregulates the expression of activating receptors involved in NK-cell-mediated target cell killing without affecting ADCC. 141
Natural killer cells kill human melanoma cells with characteristics of cancer stem cells. 140
Identification of HLA-E-specific alloreactive T lymphocytes: a cell subset that undergoes preferential expansion in mixed lymphocyte culture and displays a broad cytolytic activity against allogeneic cells. 140
EXPRESSION OF KILLER INHIBOTORY RECEPTOR (KIR) CD158B ON RESIDUAL TCRalpha/beta or gamma/delta T CELLS ON B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA (B-CLL) MODULATE THEIR CYTOTOXIC ACTIVITY 139
NK-CTLs, a novel HLA-E-restricted T-cell subset 138
Isolation, Expansion, and Characterization of Natural Killer Cells and Their Precursors as a Tool to Study Cancer Immunosurveillance 137
Interaction between novel anticancer agents and radiation in non-small cell lung cancer cell lines. 136
Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity. 136
Characterization of metabolic and molecular response of a human melanoma cell line resistant to PLX4032 134
Quantitative flow cytometric analysis of the effects of cetirizine on the expression of ICAM-1/CD54 on primary cultured nasal cells. 133
The analysis of the natural killer-like activity of human cytolytic T lymphocytes revealed HLA-E as a novel target for TCR alpha/beta-mediated recognition 132
Immune Checkpoint Inhibitors: Anti-NKG2A Antibodies on Board 132
PLX4032 resistance of patient-derived melanoma cells: crucial role of oxidative metabolism 131
Human NK cells: From surface receptors to clinical applications 131
Proliferative, phenotypic and functional and molecular characteristics of tumour-infiltrating lymphocytes obtained from unselected patients with malignant melanomas and expanded in vitro in the presence of recombinant interleukin-2 130
Dendritic cell maturation is inhibited by apoptotic bodies and promoted by necrotic cells from human melanoma 130
Melanoma cells inhibit natural killer cell function by modulating the expression of activating receptors and cytolytic activity 130
Melanoma immunoediting by NK cells. 127
Human NK cells and cancer 126
Adoptive immunotherapy with tumor-infiltrating lymphocytes and subcutaneous recombinant interleukin-2 plus interferon alfa-2a for melanoma patients with nonresectable distant disease: a phase I/II pilot trial. Melanoma Istituto Scientifico Tumori Group. 125
Morphological, phenotypic and karyotypic characterization of a novel natural-killer-cell target - evidence of involvement of MHC class-I molecules in NK cell recognition. 123
Melanoma cells inhibit NK cell functions-response 122
Whole-Exome Sequencing and cfDNA Analysis Uncover Genetic Determinants of Melanoma Therapy Response in a Real-World Setting 120
Normal epithelial cells modulating HLA class I surface molecules are susceptible to lysis mediated by CD3(+) and CD3(-) "nonspecific" killer cells. 120
Exploiting Human NK Cells in Tumor Therapy 120
Limiting dilution analysis of peripheral blood lymphocytes reacting with non-small-cell lung cancer: functionally heterogeneous effectors efficiently lyse autologous cancer cells. 118
Heterogeneity of the alpha-interferon-mediated overexpression of class-I and class-II major histocompatibility complex molecules in primary cultured cancer cells. 116
MELANOMA CELLS INTERFERE WITH THE ACTIVITY OF NK CELLS BY MODULATING THEIR PHENOTYPE AND CYTOTOXIC FUNCTION 114
Murine models to study human NK cells in human solid tumors 113
HLA-E and HLA-E-bound peptides: recognition by subsets of NK and T cells. 112
Melanoma cells inhibit natural killer cell function by modulating their phenotype 111
Hla-E-Restricted Cytolytic T Lymphocytes: Their Role in Cytomegalovirus Infection and Transplantation 111
Human cytolytic T lymphocytes expressing HLA class I-specific inhibitory receptors 105
Natural Killer Cell Effector Mechanisms Against solid tumors and leukemias and their exploitation in immunotherapy 105
Phenotipic and Functional Characterization of Human Decidual Natural Killer Cells 104
NK CELL AND TUMOR MICROENVIRONMENT INTERACTIONS IN MELANOMA 103
Recognition of the non-classical MHC class I molecule, HLA-E, by the adaptive immune system 102
HO-1 Limits the Efficacy of Vemurafenib/PLX4032 in BRAFV600E Mutated Melanoma Cells Adapted to Physiological Normoxia or Hypoxia 92
Peptides with dual binding specificity for HLA-A2 and HLA-E are encoded by alternatively spliced isoforms of the antioxidant enzymes peroxiredoxin 5 92
Guadecitabine impact on phenotype and function of peripheral blood and hematopoietic stem cell-derived NK: in vitro differentiation and proliferation 91
In vitro effects of loratadine and its active metabolite an T lymphocytes 91
The engagement of ctla-4 on primary melanoma cell lines induces antibody-dependent cellular cytotoxicity and tnf-alpha production. 90
RECOGNITION OF HLA-E BY NATURAL KILLER CELLS IS IMPACTED BY VARIATION IN CYTOMEGALOVIRUS UL40 SEQUENCES IN HAEMOPOIETIC STEM CELL TRANSPLANTATION 89
Interleukin-15 and cancer: Some solved and many unsolved questions 89
Human dendritic cells (DCs) efficiently internalize apoptotic bodies from vaccinia virus infected non Hodgkin lymphoma (NHL) cells. 88
The role of peptide in the recognition of HLA-E by cytomegalovirus-specific CD8+T cells 88
Immune Checkpoint Blockade: A Strategy to Unleash the Potential of Natural Killer Cells in the Anti-Cancer Therapy 87
Inhibitory checkpoints in human natural killer cells: IUPHAR Review 28 86
NK cells and ILCs in tumor immunotherapy 85
Polymorphism in human cytomegalovirus UL40 impacts on recognition of HLA-E by natural killer cells. 84
Targeted therapies: Friends or foes for patient's NK cell-mediated tumor immune-surveillance? 83
Titolo BOOK Chapter: NK cell effector mechanisms against solid tumors and leukemias and their exploitation in immunotherapy. Cancer Immunotherapy Principles and Practice, edited by Lisa H. Butterfield, PhD, Howard L. Kaufman, MD, FACS, and Francesco M. Marincola, MD, FACS, (Volume Editors). 80
Vitamin D plasma level can affect nivolumab drug exposure in a cohort of patients with non-small-cell lung cancer 77
Phases of apoptosis of melanoma cells, but not of normal melanocytes, differently affect maturation of myeloid dendritic cells. 66
The roles of different forms of IL-15 in human melanoma progression 63
Natural killer cell receptors regulate responses of HLA-E-restricted T cells 53
TIGIT Blockade and IL15 in Tumor Immunotherapy: Together is Better 50
Totale 13.432
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Categoria #
all - tutte 42.203
article - articoli 40.868
book - libri 359
conference - conferenze 243
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 733
Totale 84.406
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022975 0 0 87 96 47 76 73 261 59 104 47 125
2022/2023918 99 56 13 78 176 168 0 66 155 3 89 15
2023/2024535 30 62 18 84 61 104 21 20 20 17 22 76
2024/20251.810 37 121 66 89 335 213 211 219 76 99 143 201
2025/20262.945 330 114 174 229 395 279 459 201 211 276 121 156
2026/2027604 343 97 164 0 0 0 0 0 0 0 0 0
Totale 13.432