IRIS
MOSTI, LUISA
 Distribuzione geografica
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Continente #
EU - Europa 8.571
AS - Asia 10
SA - Sud America 3
Totale 8.584
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Nazione #
IT - Italia 8.571
CN - Cina 5
BR - Brasile 3
SG - Singapore 3
BD - Bangladesh 1
VN - Vietnam 1
Totale 8.584
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Città #
Genova 5.535
Genoa 1.886
Rapallo 602
Vado Ligure 541
Bordighera 7
Beijing 3
Singapore 3
Belo Horizonte 1
Cedral 1
Haiphong 1
Rio de Janeiro 1
Tianjin 1
Totale 8.582
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Nome #
1-Phenyl-1H-Indazole derivatives with analgesic and anti-inflammatory activities. 188
An efficient synthesis of functionalized 2-pyridones by direct route or via amide/enolate ammonium salt intermediates 185
3-Acetyl-5-acylpyridin-2(1H)-ones and 3-acetyl-7,8-dihydro-2,5(1H,6H)-quinolinediones: synthesis, cardiotonic activity and computational studies 166
Chemometric study and validation strategies in the structure-activity relationships of new cardiotonic agents 164
4-Dialkylamino-1-(5-substituted or unsubstituted 1-phenyl-1H-pyrazol-4-yl)butan-1-ols: synthesis and evaluation of analgesic, anti-inflammatory and platelet anti-aggregating activities 162
CoMFA and CoMSIA analyses on 1,2,3,4-tetrahydropyrrolo[3,4-b]indole and benzimidazole derivatives as selective CB2 receptor agonists. 159
Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors 154
Exploring the QSAR of pyrazolo[3,4-b]pyridine, pyrazolo[3,4-b]pyridone and pyrazolo[3,4-b]pyrimidine derivatives as antagonists for A1 adenosine receptor. 153
Affinity prediction on A1 adenosine receptor agonists: the chemometric approach 150
A chemometric approach to predict A1 agonist effect of adenosine analogues 140
Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line 140
Synthesis of 5-substituted 1-aryl-1H-pyrazole-4-acetonitriles, 4-methyl-1-phenyl-1H-pyrazole-3-carbonitrile and pharmacologically active 1-aryl-1H-pyrazole-4-acetic acids. 139
4-Substituted 1,5-diarylpyrazoles, analogues of celecoxib: synthesis and preliminary evaluation of biological properties 137
2- substituted 5-acetyl-1,6-dihydro-6-oxo-3-pyridinecarboxylates: synthesis and cardiotonic activity 137
Structural basis for selective PDE 3 inhibition: a docking study 134
CoMFA and CoMSIA analyses on 4-oxo-1,4-dihydroquinoline and 4-oxo-1,4-dihydro-1,5-, -1,6- and -1,8-naphthyridine derivatives as selective CB2 receptor agonists 133
Synthesis and Cardiotonic Activity of Novel Pyrimidine Derivatives. Crystallographic and Quantum Chemical Studies 133
4-Substituted 1-methyl-1H-indazoles with analgesic, antiinflammatory and antipyretic activities 131
Synthesis and preliminary biological evaluation of novel N-substituted 1-amino-3-[1-methyl(phenyl)-1H-indazol-4-yloxy]-propan-2-ols interesting as potential antiarrhythmic, local anaesthetic and analgesic agents 131
An updated topographical model for phosphodiesterase 4 (PDE4) catalytic site 127
Synthesis, molecular modeling studies and pharmacological activity of selective A1 receptor antagonists 125
A New Milrinone analog: Role of Binding to A1 Adenosine Receptor in its Positive Inotropic Effect on Isolated Guinea Pig and Rat Atria 124
New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation 123
DNA-psoralens molecular recognition using molecular dynamics 122
Exploring the binding features of rimonabant analogues and acyclic CB1 antagonists: docking studies and QSAR analysis 119
Ionization Behaviour and Tautomerism-Dependent Lipophilicity of Pyridine-2(1H)-one Cardiotonic Agents 119
Synthesis and in vitro antiplatelet activity of new 4-(1-piperazinyl)coumarin derivatives. Human platelet phosphodiesterase 3 inhibitory properties of the two most effective compounds described and molecular modeling study on their interactions with phosphodiesterase 3A catalytic site 118
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Exploring the molecular basis of selectivity in A1 adenosine receptors antagonist: a case study 116
Zups: the evolution of a new class of molecular descriptors 115
Unprecedented one-pot stereoselective synthesis of Knoevenagel-type derivatives via in situ condensation of N-methyleniminium salts of ethylenethiourea and ethyleneurea with active methylene reagents 115
Synthesis of 1-(2-chloro-2-phenylethyl)-6-methylthio-1-H-pyrazolo[3,4-d]pyrimidines 4-amino substituted and their biological evaluation 113
Insights into Structure-Activity Relationships from Lipophilicity Profiles of Pyridin-2(1H)-one Analogs of the Cardiotonic Agent Milrinone 113
Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells 113
Synthesis and Pharmacological Characterization of Functionalized 2-Pyridones Structurally Related to the Cardiotonic Agent Milrinone 113
New halogenated 4-aminopyrazolo[3,4-b]pyridines A1 adenosine receptor ligands 112
Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation 112
Substituted pyrazolo[3,4-b]pyridines as potent A1 adenosine antagonists: synthesis, biological evaluation, and development of an A1 bovine receptor model. 111
2-Pyridone derivatives as inotropic agents: synthesis, pharmacology and molecular modeling study 111
Structure-based Design, Parallel Synthesis, SAR and Molecular Modelling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea Derivatives. 106
Synthesis of indole imminun salts as key-intermediates in a convergent multi-step one-pot stereoselective synthesis of new potent antiproliferative Knoevenagel-type agent 105
Quinolinedione nucleus as a novel scaffold for A1 and A2A adenosine receptor antagonists. 105
Towards the identification of the cardiac cAMP phosphodiesterase receptor site 104
Development of a new topographical model for myocardial cGI-PDE catalytic site 104
Synthesis and biological data of 4-amino-1-(2-chloro-2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl esters, a new series of A1-adenosine receptor (A1AR) ligands 104
Novel angular furo and thieno-quinolinones: synthesis and preliminary photobiological studies 104
Synthesis and biological evaluation of azole derivatives, analogues of bifonazole, with a phenylisoxazolyl or phenylpyrimidinyl moiety 103
2-Pyridone derivatives as inotropic agents: synthesis, pharmacology and molecular modeling study 102
New pyrazolo[3,4-b]pyridones as selective A1 adenosine receptor antagonists: synthesis, biological evaluation and molecular modeling studies 100
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Toward the identification of the cardiac cGMP inhibited-phosphodiesterase catalytic site 97
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines 97
New milrinone analogues:in vitro study of structure-activity relationships for positive inotropic effect, antagonism towards endogenous adenosine and inhibition of cardiac type III phosphodiesterase 97
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Modulazioni Strutturali in O-[2-(N-Ftalimmido)etil] Acil(Aril)Tiocarbammati, Inibitori Non-Nucleosidici della Transcrittasi Inversa di HIV-1 94
Synthesis of pyrazolo[3,4-d]pyridines selective antagonists of A1 adenosine receptors 94
Reaction of Sulfene with Heterocyclic N,N-Disubstituted alfa-Amino methyleneketones.XI. Synthesis of 1,2-Oxathiino[5,6-d]-1-benzoxepin Derivatives. 92
Molecular Modeling of DNA-psoralens complexes 91
QSAR study on new cardiotonic agents related to milrinone 90
Exploring the binding features of rimonabant analogues and acyclic CB1 antagonists: docking studies and 3D-QSAR analysis 89
Reaction of Sulfene with Heterocyclic N, N-Disubstituted alfa-Amino methyleneketones. IX. Synthesis of 1,2-Oxathiino [6,5-e] indole Derivatives. 89
Androstane derivatives: synthesis of substituted 6'-H-androst-2-eno*3,2-b*pyran-6'-ones. 86
Riconoscimento molecolare DNA-psoraleni mediante tecniche di dinamica molecolare 85
In silico rationalization of the structural and physicochemical requirements for photobiological activity in angelicine derivatives and their heteroanalogues 85
Synthesis, Biological Evaluation and Molecular Modeling Studies on Benzothiadiazine Derivatives as PDE4 Selective Inhibitors 84
Flavonoidverbindungen und Allantoin aus Anchusa officinalis L. 81
Synthesis, antimicrobial activity and molecular modelling studies of halogenated 4-[1H-imidazol-1-yl(phenyl)methyl]-1,5-diphenyl-1H-pyrazoles 78
Inotropic Agents. Synthesis and Structure-Activity Relationships of New Milrinone Related cAMP PDEIII inhibitors 76
New pyrazolo[3,4-b]pyridines antagonist of A1 adenosine receptors 74
omega-Dialkylaminoalkil Ethers of Phenyl-(5-substituted 1-phenyl-1H-pyrazol-4-yl)methanols with Analgesic and Anti-inflammatory Activity 74
Glycoside und Depside aus den Blättern von Castanea sativa Mill. 74
Studio computazionale di complessi di intercalazione al buio DNA-psoraleni Pavia, 27-29 maggio 1999 70
Computational studies of the binding mode and 3D-QSAR analyses of symmetric formimidoester disulfides: a new class of non-nucleoside HIV-1 reverse transcriptase inhibitors 70
Synthesis and photobiological properties of 3-acylangelicins, 3-alkoxycarbonyl-angelicins and related derivatives 67
Zupan's descriptors in QSAR applied to the study of a new class of cardiotonic agents 66
Synthesis of new pyrazolo[3,4-b]pyridines: new selective A1 adenosine receptor antagonists 61
Acylthiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: docking studies and ligand-based CoMFA and CoMSIA analyses 49
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: docking-based CoMFA and CoMSIA analyses 20
Rational design, synthesis and biological evaluation of new 1,5-diarylpyrazole derivatives as CB1 receptor antagonists, structurally related to rimonabant 18
Synthesis of N-substituted-N-acylthioureas of 4-substituted piperazines endowed with local anaesthetic, antihyperlipidemic, antiproliferative activities and antiarrythmic, analgesic, antiaggregating actions 12
Totale 8.681
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Categoria #
all - tutte 26.631
article - articoli 21.996
book - libri 0
conference - conferenze 4.635
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.262
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021281 0 0 0 26 42 22 17 30 37 38 26 43
2021/2022949 43 85 70 91 26 43 63 254 39 85 45 105
2022/2023730 66 47 7 85 122 121 0 37 104 5 117 19
2023/2024361 20 59 11 51 38 51 20 15 9 12 35 40
2024/20251.322 24 91 40 105 189 130 99 248 72 62 131 131
2025/2026653 285 58 167 143 0 0 0 0 0 0 0 0
Totale 8.681