TONELLI, MICHELE
TONELLI, MICHELE
100006 - Dipartimento di Farmacia
A Fragment‑Based Computational Strategy for the Discovery of New‑Generation Glutaminase Inhibitors
2026-01-01 Allahi, Shahin; Trombetti Gabriele, Antonio; Poggialini, Federica; Vagaggini, Chiara; Dreassi, Elena; Tonelli, Michele; Francesconi, Valeria; Schenone, Silvia; Carbone, Anna; Fossa, Paola; D'Ursi, Pasqualina
An in silico fragment-based strategy for the rational design of new glutaminase inhibitors
2025-01-01 Allahi, Shahin; Trombetti Gabriele, Antonio; Poggialini, Federica; Vagaggini, Chiara; Dreassi, Elena; Tonelli, Michele; Schenone, Silvia; Fossa, Paola; Carbone, Anna; D’Ursi, Pasqualina
Antitubercular and antiprotozoal activities of quinolizidinyl/pyrrolizidinylalkyliminophenazines
2012-01-01 Novelli, Federica; Tasso, Bruno; Tonelli, Michele; Boido, Vito; Sparatore, Fabio; Anna, Sparatore; Paola, Molicotti; Stefania, Zanetti
Celecoxib, a COX-2 inhibitor, blocks microglial activation induced by a neurotoxic conformer of hPrP90-231
2012-01-01 Villa, Valentina; Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Tonelli, Michele; Tasso, Bruno; Sparatore, Fabio; Silvia, Leone; Fucile, Carmen; Florio, Tullio
Design of New GLS1 Allosteric Inhibitors by the Fragment_Based Strategy
2026-01-01 Allahi, Shahin; Trombetti Gabriele Antonio, ; Federica, Poggialini; Chiara, Vagaggini; Elena, Dreassi; Tonelli, Michele; Francesconi, Valeria; Schenone, Silvia; Carbone, Anna; Fossa, Paola; Pasqualina, D'Ursi
Fragment based design of GLS1 allosteric inhibitors for cancer therapy
2025-01-01 Allahi, S.; Trombetti, G. A.; Poggialini, F.; Vagaggini, C.; Dreassi, E.; Tonelli, M.; Schenone, S.; Fossa, P.; D’Ursi, P.; Carbone, A.
GLUTAMINASE 1 (GLS1) ALLOSTERIC INHIBITORS: SYNTHESIS OF KEY INTERMEDIATES
2026-01-01 Vezzoli, M.; Francesconi, V.; Poggialini, F.; Vagaggini, C.; Schenone, S.; Dreassi, E.; Fossa, P.; D’Ursi, P.; Tonelli, M.; Carbone, A.
Identification of a theranostic prodrug candidate against glioblastoma
2025-01-01 Carbone, A.; Vagaggini, C.; Francesconi, V.; Salis, A.; Poggialini, F.; Petroni, D.; D’Antona, L.; Pozzi, C.; Grossi, G.; Tonelli, M.; Musumeci, F.; Menichetti, L.; Dreassi, E.; Schenone, S.
New naphtho- and anthraquinone derivatives as Cholinesterase inhibitors for the treatment of Alzheimer's disease
2019-01-01 Campora, Marta; Marco, Catto; Tonelli, Michele; Tasso, Bruno
Quinolizidinyl derivatives of bi- and tricyclic systems as AChE/BchE and beta-amyloid aggregation inhibitors,
2011-01-01 Tasso, Bruno; Novelli, Federica; Marco, Catto; Orazio, Nicolotti; Tonelli, Michele; Gerolamo, Vettoretti; Boido, Vito; Sparatore, Fabio; Angelo, Carotti
Quinone-based derivatives: a new class of multi-target agents against Alzheimer’s disease
2019-01-01 Campora, Marta; Catto, Marco; Relini, Annalisa; Canale, Claudio; Tasso, Bruno; Tonelli, Michele
The fragment-based strategy: an effective approach for designing new small molecules that act as GLS1 inhibitors.
2026-01-01 Allahi, Shahin; Antonio Trombetti, Gabriele; Poggialini, Federica; Vagaggini, Chiara; Dreassi, Elena; Tonelli, Michele; Schenone, Silvia; Carbone, Anna; Fossa, Paola; D'Ursi, Pasqualina
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A Fragment‑Based Computational Strategy for the Discovery of New‑Generation Glutaminase Inhibitors | 1-gen-2026 | Allahi, Shahin; Trombetti Gabriele, Antonio; Poggialini, Federica; Vagaggini, Chiara; Dreassi, Elena; Tonelli, Michele; Francesconi, Valeria; Schenone, Silvia; Carbone, Anna; Fossa, Paola; D'Ursi, Pasqualina | |
| An in silico fragment-based strategy for the rational design of new glutaminase inhibitors | 1-gen-2025 | Allahi, Shahin; Trombetti Gabriele, Antonio; Poggialini, Federica; Vagaggini, Chiara; Dreassi, Elena; Tonelli, Michele; Schenone, Silvia; Fossa, Paola; Carbone, Anna; D’Ursi, Pasqualina | |
| Antitubercular and antiprotozoal activities of quinolizidinyl/pyrrolizidinylalkyliminophenazines | 1-gen-2012 | Novelli, Federica; Tasso, Bruno; Tonelli, Michele; Boido, Vito; Sparatore, Fabio; Anna, Sparatore; Paola, Molicotti; Stefania, Zanetti | |
| Celecoxib, a COX-2 inhibitor, blocks microglial activation induced by a neurotoxic conformer of hPrP90-231 | 1-gen-2012 | Villa, Valentina; Corsaro, Alessandro; THELLUNG DE COURTELARY, Stefano; Tonelli, Michele; Tasso, Bruno; Sparatore, Fabio; Silvia, Leone; Fucile, Carmen; Florio, Tullio | |
| Design of New GLS1 Allosteric Inhibitors by the Fragment_Based Strategy | 1-gen-2026 | Allahi, Shahin; Trombetti Gabriele Antonio, ; Federica, Poggialini; Chiara, Vagaggini; Elena, Dreassi; Tonelli, Michele; Francesconi, Valeria; Schenone, Silvia; Carbone, Anna; Fossa, Paola; Pasqualina, D'Ursi | |
| Fragment based design of GLS1 allosteric inhibitors for cancer therapy | 1-gen-2025 | Allahi, S.; Trombetti, G. A.; Poggialini, F.; Vagaggini, C.; Dreassi, E.; Tonelli, M.; Schenone, S.; Fossa, P.; D’Ursi, P.; Carbone, A. | |
| GLUTAMINASE 1 (GLS1) ALLOSTERIC INHIBITORS: SYNTHESIS OF KEY INTERMEDIATES | 1-gen-2026 | Vezzoli, M.; Francesconi, V.; Poggialini, F.; Vagaggini, C.; Schenone, S.; Dreassi, E.; Fossa, P.; D’Ursi, P.; Tonelli, M.; Carbone, A. | |
| Identification of a theranostic prodrug candidate against glioblastoma | 1-gen-2025 | Carbone, A.; Vagaggini, C.; Francesconi, V.; Salis, A.; Poggialini, F.; Petroni, D.; D’Antona, L.; Pozzi, C.; Grossi, G.; Tonelli, M.; Musumeci, F.; Menichetti, L.; Dreassi, E.; Schenone, S. | |
| New naphtho- and anthraquinone derivatives as Cholinesterase inhibitors for the treatment of Alzheimer's disease | 1-gen-2019 | Campora, Marta; Marco, Catto; Tonelli, Michele; Tasso, Bruno | |
| Quinolizidinyl derivatives of bi- and tricyclic systems as AChE/BchE and beta-amyloid aggregation inhibitors, | 1-gen-2011 | Tasso, Bruno; Novelli, Federica; Marco, Catto; Orazio, Nicolotti; Tonelli, Michele; Gerolamo, Vettoretti; Boido, Vito; Sparatore, Fabio; Angelo, Carotti | |
| Quinone-based derivatives: a new class of multi-target agents against Alzheimer’s disease | 1-gen-2019 | Campora, Marta; Catto, Marco; Relini, Annalisa; Canale, Claudio; Tasso, Bruno; Tonelli, Michele | |
| The fragment-based strategy: an effective approach for designing new small molecules that act as GLS1 inhibitors. | 1-gen-2026 | Allahi, Shahin; Antonio Trombetti, Gabriele; Poggialini, Federica; Vagaggini, Chiara; Dreassi, Elena; Tonelli, Michele; Schenone, Silvia; Carbone, Anna; Fossa, Paola; D'Ursi, Pasqualina |