IRIS
MELLONI, EDON
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 29.829
AS - Asia 2.587
NA - Nord America 2.583
SA - Sud America 240
Continente sconosciuto - Info sul continente non disponibili 168
AF - Africa 46
OC - Oceania 21
Totale 35.474
Salva come PNG Salva come JPEG
Nazione #
IT - Italia 29.349
US - Stati Uniti d'America 2.394
SG - Singapore 1.159
CN - Cina 670
VN - Vietnam 399
FR - Francia 241
BR - Brasile 144
BD - Bangladesh 122
CA - Canada 74
HK - Hong Kong 69
DE - Germania 51
AR - Argentina 44
GB - Regno Unito 38
JP - Giappone 34
FI - Finlandia 32
MX - Messico 29
JM - Giamaica 23
AU - Australia 21
IN - India 20
CH - Svizzera 19
CO - Colombia 19
NL - Olanda 16
ID - Indonesia 15
IQ - Iraq 13
CR - Costa Rica 12
ES - Italia 12
HN - Honduras 12
TR - Turchia 11
PH - Filippine 10
ZA - Sudafrica 10
AE - Emirati Arabi Uniti 9
EC - Ecuador 8
GT - Guatemala 8
UA - Ucraina 8
VE - Venezuela 8
IE - Irlanda 7
MA - Marocco 7
NI - Nicaragua 7
TT - Trinidad e Tobago 7
KR - Corea 6
PL - Polonia 6
PR - Porto Rico 6
RU - Federazione Russa 6
SA - Arabia Saudita 6
JO - Giordania 5
PE - Perù 5
RO - Romania 5
TH - Thailandia 5
TW - Taiwan 5
UZ - Uzbekistan 5
BE - Belgio 4
CL - Cile 4
DZ - Algeria 4
EG - Egitto 4
KE - Kenya 4
KZ - Kazakistan 4
MY - Malesia 4
RS - Serbia 4
SE - Svezia 4
BA - Bosnia-Erzegovina 3
BO - Bolivia 3
CZ - Repubblica Ceca 3
SK - Slovacchia (Repubblica Slovacca) 3
AL - Albania 2
AO - Angola 2
AZ - Azerbaigian 2
BM - Bermuda 2
CY - Cipro 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
IL - Israele 2
LB - Libano 2
LT - Lituania 2
MT - Malta 2
NG - Nigeria 2
NO - Norvegia 2
PK - Pakistan 2
PY - Paraguay 2
SC - Seychelles 2
SN - Senegal 2
SV - El Salvador 2
TG - Togo 2
TN - Tunisia 2
UY - Uruguay 2
AT - Austria 1
AW - Aruba 1
BB - Barbados 1
BG - Bulgaria 1
BW - Botswana 1
BY - Bielorussia 1
BZ - Belize 1
CG - Congo 1
CI - Costa d'Avorio 1
CW - ???statistics.table.value.countryCode.CW??? 1
EE - Estonia 1
GE - Georgia 1
GF - Guiana Francese 1
GR - Grecia 1
HU - Ungheria 1
Totale 35.298
Salva come PNG Salva come JPEG
Città #
Genova 19.018
Genoa 5.923
Rapallo 2.408
Vado Ligure 1.761
San Jose 709
Singapore 563
Lauterbourg 218
Ashburn 217
Ho Chi Minh City 116
New York 114
Beijing 94
Hanoi 71
Santa Clara 66
Hong Kong 61
Phoenix 58
Frankfurt am Main 44
Los Angeles 40
Council Bluffs 35
Helsinki 32
Milan 32
Tokyo 32
Bordighera 29
Rome 25
Chicago 23
Da Nang 22
Dallas 21
Haiphong 21
Zurich 19
Mexico City 18
Buffalo 17
Tianjin 17
Montreal 16
Kingston 15
Amsterdam 13
Atlanta 13
Brooklyn 13
São Paulo 13
Houston 12
Naples 12
Toronto 12
Washington 12
Jacksonville 11
San Francisco 11
London 10
Philadelphia 10
San José 10
Charlotte 9
Madrid 9
Orem 9
Des Moines 8
Las Vegas 8
Baghdad 7
Bari 7
Dublin 7
Guatemala City 7
Rio de Janeiro 7
Biên Hòa 6
Brasília 6
Hải Dương 6
Managua 6
Miami 6
Quảng Ngãi 6
Sydney 6
Abu Dhabi 5
Bogotá 5
Cardiff 5
City of London 5
Cleveland 5
Detroit 5
Dhaka 5
Guangzhou 5
Istanbul 5
Jeddah 5
Johannesburg 5
Mumbai 5
Newark 5
Palermo 5
Paris 5
Sumter 5
Tashkent 5
The Bronx 5
Turin 5
Warsaw 5
Wuhan 5
Acalanes Ridge 4
Amman 4
Belgrade 4
Cairo 4
Durham 4
Edmonton 4
Figino 4
Florence 4
Greensboro 4
Iowa City 4
Marseille 4
Melbourne 4
Memphis 4
New Orleans 4
Nha Trang 4
Ninh Bình 4
Totale 32.296
Salva come PNG Salva come JPEG
Nome #
Activation of calpain 1 and protein kinase C alpha promotes a constitutive expression and release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 327
"Intracellular calpastatin proteolysis: a salvage mechanism or a prelude to cell damage?" 277
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 255
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 252
Evidence for alteration of calpain/calpastatin system in PBMC of cystic fibrosis patients 240
Calpain inhibition promotes the rescue of F(508)del-CFTR in PBMC from cystic fibrosis patients. 227
Role of the calpain-calpastatin system in the density-dependent growth arrest 221
Activation of Ca2+-dependent proteolysis in skeletal muscle and heart in cancer cachexia. 220
Clinical Severity of β-thalassaemia/Hb E Disease Is Associated with Differential Activities of the Calpain-Calpastatin Proteolytic System. 216
Glycine taken up through GLYT1 and GLYT2 heterotransporters into glutamatergic axon terminals of mouse spinal cord elicits release of glutamate by homotransporter reversal and through anion channels 215
Acyl-CoA-binding protein is a potent m-calpain activator 215
A vincristine-resistant murine erythroleukemia cell line secretes a differentiation enhancing factor. 215
Glia re-sealed particles freshly prepared from adult rat brain are competent for exocytotic release of glutamate 213
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain. 209
Role of the regulatory domain of calpastatin in the autoproteolytic activation of calpain 208
Modulation of the calpain autoproteolysis by calpastatin and phospholipids 204
Autolysis of human erythrocytes calpain produces two active enzyme forms with different cell localization 203
Characterization of a new p94-like calpain form in human lymphocytes 200
Characterization of the calpain/calpastatin system in human hemopoietic cell lines 199
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 196
Cell protection from Ca2+-overloading by bioactive molecules extracted from olive pomace 196
Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex. 196
Activation by hemoglobin of the Ca2+-requiring neutral proteinase of human erythrocytes: structural requirements. 194
Conformational changes of calpain from human erythrocytes in the presence of Ca2+. 193
Effect of extremely low frequency magnetic fields on calpain activation 193
Axonal damage and demyelination in long-term dorsal root ganglia cultures from a rat model of Charcot-Marie-Tooth type 1A disease 193
Activation of neutrophil calpain following its translocation to the plasma membrane induced by phorbol ester or fMet-Leu-Phe.. 192
Involvement of exon 6-mediated calpastatin intracellular movements in the modulation of calpain activation. 189
Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase. 189
Degradation of CFTR-generated protein clusters by calpain: A physiological or a pathological role? 184
Pathological role of the calpain/calpastatin system in cystic fibrosis 184
Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli 184
Carbon tetrachloride-induced inhibition of protein kinase C in isolated rat hepatocytes. 183
IGF-I induced rapid recruitment of integrin β1 to lipid rafts is Caveolin-1 dependent 183
Inactivation of hepatocyte protein kinase C by carbon tetrachloride: involvement of drug's metabolic activation and prooxidant effect. 182
The calpain-calpastatin system in mammalian cells: properties and possible functions 182
The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes 180
Activation of NADPH oxidase and phosphorylation of membrane proteins in human neutrophils: coordinate inhibition by a surface antigen-directed monoclonal antibody. 178
Activation of PKC-beta isoforms mediates HNE-induced MCP-1 release by macrophages 177
Changes during fasting in the activity of a specific lysosomal proteinase, fructose-1,6-bisphosphatase converting enzyme. 175
A dual role for the Ca2+-requiring proteinase in the degradation of hemoglobin by erythrocyte membrane proteinases. 174
Glucose 6-phosphate dehydrogenase activity in membranes of erythrocytes from normal individuals and subjects with Mediterranean G6PD deficiency. 174
Characterization of the defective calpain-endogenous calpain inhibitor system in erythrocytes from Milan hypertensive rats. 174
Characterization of the calpastatin defect in erythrocytes from patients with essential hypertension. 173
Regulation of calpain activity in rat brain with altered Ca2+ homeostasis 173
Properties and intracellular localization of calpain activator protein 173
Cathepsin M: a lysosomal proteinase with aldolase-inactivating activity 172
Changes in rabbit-liver lysosomes and fructose 1,6-bisphosphatase induced by cold and fasting. 172
Changes in calpastatin localization and expression during calpain activation: a new mechanism for the regulation of intracellular Ca(2+)-dependent proteolysis. 171
Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase. 171
Characterization of the inactive form of fructose-1,6-bisphosphate aldolase isolated from livers of fasted rabbits. 171
Molecular events involved in the activation of calpain from human erythrocytes 170
On the mechanism of inhibition of fructose 1,6-bisphosphatase by fructose 2,6-bisphosphate. 170
Changes in intracellular localization of calpastatin during calpain activation 169
Binding of Zn2+ to rabbit muscle fructose 1,6-bisphosphatase and its effect on the catalytic properties. 169
Multiple rat brain calpastatin forms are produced by distinct starting points and alternative splicing of the N-terminal exons. 169
"Association of calpastatin with inactive calpain: a novel mechanism to control the activation of the protease?" 169
Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process. 169
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein. 168
Interactions of Zn2+ and Mg2+ with rabbit liver fructose 1,6 bisphosphatase. 167
Interaction between Calpain-1 and HSP90: New Insights into the Regulation of Localization and Activity of the Protease. 167
The role of calpain in the selective increased phosphorylation of the anion-transport protein in red cell of hypertensive subjects. 166
The calpain-calpastatin system in cystic fibrosis: physiopathological implications 166
Effects of ethanol metabolism on PKC activity in isolated rat hepatocytes. 166
Antisense oligodeoxynucleotide inhibition of delta protein kinase C expression accelerates induced differentiation of murine erythroleukaemia cells 165
Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90. 164
Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation. 164
Cytosolic calcium dependent proteinase of human erythrocytes: formation of an enzyme-natural inhibitor complex induced by Ca2+ ions. 163
Age-dependent degradation of calpastatin in kidney of hypertensive rats 162
Changes in intracellular calpastatin localization are mediated by reversible phosphorylation 161
Extralysosomal protein degradation. 160
Identification of a novel neutrophil membrane protein involved in modulation of oxidative burst. 160
Binding of monoclonal antibody to cathepsin M located on the external surface of rabbit lysosomes. 160
Comparative patterns of 'in vitro' oxidative hemolysis of normal and glucose 6-phosphate dehydrogenase (G6PD)-deficient erythrocytes. 160
“In vivo degradation of Nitric-Oxide Synthase isozymes by Calpain is regulated by HSP90” 160
Inactivation of fructose 1,6-bisphosphatase by a lysosomal proteinase is reversed by cystamine. 158
Biochemical responses in activated human neutrophils mediated by protein kinase C and a Ca2+-requiring proteinase. 158
"Cytosolic levels of calpastatin are regulated by limited proteolysis" 158
Ethanol-induced effects on expression level, activity and distribution of protein kinase C isoforms in rat liver Golgi apparatus 158
Adaptive modifications in the calpain/calpastatin system in brain cells after persistent alteration in Ca2+ homeostasis 158
The plasma membrane calcium pump is the preferred calpain substrate within the erythrocyte 157
Mechanisms of inactivation of hepatocyte protein kinase C isoforms following acute ethanol treatment 157
Inactivation of liver aldolase in fasting rabbits: evidence for the accumulation of two different immunoreactive forms. 157
Role of calpain in the regulation of CFTR (cystic fibrosis transmembrane conductance regulator) turnover 157
Selective Pro-Inflammatory Activation of Astrocytes by High Mobility Group Box 1 Protein Signaling 156
Changes in activity of fructose-1,6-bisphosphate aldolase in livers of fasted rabbits and accumulation of crossreacting immune material. 156
Decreased level of calpain inhibitor activity in kidney from Milan hypertensive rats. 155
Cytosolic levels of calpastatin are regulated by limited proteolysis 155
Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation 154
A Novel signalling mechanism promoting Ca(2+) driven cell responses through high-mobility group box-1/NMDA receptor interaction. 154
Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein 154
Phosphorylation and proteolytic modification of specific cytoskeletal proteins in human neutrophils stimulated by phorbol 12-myristate 13-acetate. 153
Fructose 1,6-bisphosphatase: properties of the neutral enzyme and its modification by proteolytic enzymes. 153
Isolation and characterization of calpain activator protein from bovine brain. 152
Fructose 1,6-bisphosphatase: the role of lysosomal enzymes in the modification of catalytic and structural properties. 152
Two cytosolic, Ca2+-dependent, neutral proteinases from rabbit liver: purification and properties of the proenzymes. 152
The calpastatin defect in hypertension is possibly due to a specific degradation by calpain. 152
Depletion of protein kinase C induced by an anti HLA class I monoclonal antibody in phytohemagglutinin activated human T cells. 151
ATP induces the release of a neutral serine proteinase and enhances the production of superoxide anion in membranes from phorbol ester-activated neutrophils. 151
Isovalerylcarnitine is a specific activator of the high calcium requiring calpain forms. 150
Totale 17.969
Salva come PNG Salva come JPEG
Categoria #
all - tutte 104.386
article - articoli 91.357
book - libri 597
conference - conferenze 10.267
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 2.165
Totale 208.772
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.576 0 0 195 313 122 186 209 610 130 291 117 403
2022/20232.879 260 168 27 370 450 563 1 197 526 13 267 37
2023/20241.339 66 181 13 141 172 316 49 51 78 35 73 164
2024/20254.345 233 319 114 269 628 475 368 627 198 162 408 544
2025/20266.378 814 123 310 463 825 676 1.134 278 570 593 236 356
2026/20271.351 729 149 473 0 0 0 0 0 0 0 0 0
Totale 35.474