IRIS
MELLONI, EDON
 Distribuzione geografica
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Continente #
EU - Europa 29.662
AS - Asia 2.491
NA - Nord America 1.373
SA - Sud America 189
AF - Africa 42
OC - Oceania 21
Totale 33.778
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Nazione #
IT - Italia 29.222
US - Stati Uniti d'America 1.288
SG - Singapore 1.155
CN - Cina 666
VN - Vietnam 390
FR - Francia 229
BR - Brasile 118
HK - Hong Kong 65
BD - Bangladesh 61
DE - Germania 50
AR - Argentina 40
JP - Giappone 34
CA - Canada 32
FI - Finlandia 32
GB - Regno Unito 28
MX - Messico 25
AU - Australia 21
IN - India 20
CH - Svizzera 19
NL - Olanda 15
ID - Indonesia 13
IQ - Iraq 13
CO - Colombia 10
ZA - Sudafrica 10
AE - Emirati Arabi Uniti 9
JM - Giamaica 9
TR - Turchia 9
ES - Italia 8
PH - Filippine 8
IE - Irlanda 6
KR - Corea 6
MA - Marocco 6
RU - Federazione Russa 6
UA - Ucraina 6
JO - Giordania 5
PL - Polonia 5
SA - Arabia Saudita 5
TW - Taiwan 5
UZ - Uzbekistan 5
VE - Venezuela 5
CR - Costa Rica 4
DZ - Algeria 4
EG - Egitto 4
HN - Honduras 4
KE - Kenya 4
KZ - Kazakistan 4
RO - Romania 4
RS - Serbia 4
SE - Svezia 4
TH - Thailandia 4
BO - Bolivia 3
CL - Cile 3
CZ - Repubblica Ceca 3
EC - Ecuador 3
PE - Perù 3
AL - Albania 2
AO - Angola 2
BE - Belgio 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GT - Guatemala 2
IL - Israele 2
LT - Lituania 2
MT - Malta 2
MY - Malesia 2
NG - Nigeria 2
NI - Nicaragua 2
PK - Pakistan 2
PY - Paraguay 2
SN - Senegal 2
TG - Togo 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AT - Austria 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CI - Costa d'Avorio 1
CY - Cipro 1
EE - Estonia 1
GR - Grecia 1
HU - Ungheria 1
IR - Iran 1
KW - Kuwait 1
LB - Libano 1
LK - Sri Lanka 1
MD - Moldavia 1
MK - Macedonia 1
NO - Norvegia 1
NP - Nepal 1
OM - Oman 1
PA - Panama 1
PR - Porto Rico 1
SK - Slovacchia (Repubblica Slovacca) 1
TN - Tunisia 1
Totale 33.778
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Città #
Genova 19.018
Genoa 5.918
Rapallo 2.408
Vado Ligure 1.761
San Jose 577
Singapore 562
Lauterbourg 218
Ashburn 115
Ho Chi Minh City 114
New York 95
Beijing 93
Hanoi 69
Hong Kong 59
Santa Clara 47
Frankfurt am Main 44
Helsinki 32
Tokyo 32
Bordighera 29
Council Bluffs 24
Da Nang 21
Haiphong 21
Zurich 19
Los Angeles 18
Mexico City 18
Tianjin 17
Buffalo 13
Montreal 13
São Paulo 13
Amsterdam 12
Chicago 9
Dallas 9
San Francisco 9
Toronto 9
Madrid 8
Orem 8
Rome 8
Baghdad 7
Des Moines 7
Dublin 7
Biên Hòa 6
Hải Dương 6
Kingston 6
London 6
Milan 6
Quảng Ngãi 6
Rio de Janeiro 6
Sydney 6
Abu Dhabi 5
Atlanta 5
Cardiff 5
City of London 5
Guangzhou 5
Johannesburg 5
Mumbai 5
Phoenix 5
Tashkent 5
Warsaw 5
Wuhan 5
Acalanes Ridge 4
Amman 4
Bari 4
Belgrade 4
Istanbul 4
Jeddah 4
Marseille 4
Melbourne 4
Naples 4
Nha Trang 4
Ninh Bình 4
Palermo 4
Paris 4
Shanghai 4
Ankara 3
Bogotá 3
Bologna 3
Brno 3
Brooklyn 3
Buenos Aires 3
Cairo 3
Campinas 3
Can Tho 3
Catania 3
Changsha 3
Charlotte 3
Curtea de Argeş 3
Dhaka 3
Fortaleza 3
Houston 3
Jacksonville 3
Nairobi 3
Osasco 3
Phủ Lý 3
Quezon City 3
Quận Ba 3
San José 3
Tây Ninh 3
Vĩnh Long 3
Addis Ababa 2
Algiers 2
Almaty 2
Totale 31.701
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Nome #
Activation of calpain 1 and protein kinase C alpha promotes a constitutive expression and release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 312
"Intracellular calpastatin proteolysis: a salvage mechanism or a prelude to cell damage?" 266
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 245
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 239
Evidence for alteration of calpain/calpastatin system in PBMC of cystic fibrosis patients 223
Activation of Ca2+-dependent proteolysis in skeletal muscle and heart in cancer cachexia. 215
A vincristine-resistant murine erythroleukemia cell line secretes a differentiation enhancing factor. 210
Clinical Severity of β-thalassaemia/Hb E Disease Is Associated with Differential Activities of the Calpain-Calpastatin Proteolytic System. 210
Role of the calpain-calpastatin system in the density-dependent growth arrest 209
Glia re-sealed particles freshly prepared from adult rat brain are competent for exocytotic release of glutamate 206
Acyl-CoA-binding protein is a potent m-calpain activator 204
Glycine taken up through GLYT1 and GLYT2 heterotransporters into glutamatergic axon terminals of mouse spinal cord elicits release of glutamate by homotransporter reversal and through anion channels 203
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain. 202
Autolysis of human erythrocytes calpain produces two active enzyme forms with different cell localization 199
Calpain inhibition promotes the rescue of F(508)del-CFTR in PBMC from cystic fibrosis patients. 198
Modulation of the calpain autoproteolysis by calpastatin and phospholipids 197
Role of the regulatory domain of calpastatin in the autoproteolytic activation of calpain 192
Characterization of a new p94-like calpain form in human lymphocytes 191
Characterization of the calpain/calpastatin system in human hemopoietic cell lines 191
Effect of extremely low frequency magnetic fields on calpain activation 189
Activation by hemoglobin of the Ca2+-requiring neutral proteinase of human erythrocytes: structural requirements. 189
Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex. 188
Conformational changes of calpain from human erythrocytes in the presence of Ca2+. 186
Cell protection from Ca2+-overloading by bioactive molecules extracted from olive pomace 185
Activation of neutrophil calpain following its translocation to the plasma membrane induced by phorbol ester or fMet-Leu-Phe.. 184
Axonal damage and demyelination in long-term dorsal root ganglia cultures from a rat model of Charcot-Marie-Tooth type 1A disease 184
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 183
Involvement of exon 6-mediated calpastatin intracellular movements in the modulation of calpain activation. 182
Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase. 182
Pathological role of the calpain/calpastatin system in cystic fibrosis 179
Carbon tetrachloride-induced inhibition of protein kinase C in isolated rat hepatocytes. 178
The calpain-calpastatin system in mammalian cells: properties and possible functions 176
Inactivation of hepatocyte protein kinase C by carbon tetrachloride: involvement of drug's metabolic activation and prooxidant effect. 175
IGF-I induced rapid recruitment of integrin β1 to lipid rafts is Caveolin-1 dependent 175
Degradation of CFTR-generated protein clusters by calpain: A physiological or a pathological role? 174
Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli 173
Characterization of the defective calpain-endogenous calpain inhibitor system in erythrocytes from Milan hypertensive rats. 172
The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes 171
Changes in calpastatin localization and expression during calpain activation: a new mechanism for the regulation of intracellular Ca(2+)-dependent proteolysis. 170
Characterization of the calpastatin defect in erythrocytes from patients with essential hypertension. 169
A dual role for the Ca2+-requiring proteinase in the degradation of hemoglobin by erythrocyte membrane proteinases. 169
Activation of NADPH oxidase and phosphorylation of membrane proteins in human neutrophils: coordinate inhibition by a surface antigen-directed monoclonal antibody. 169
Cathepsin M: a lysosomal proteinase with aldolase-inactivating activity 168
Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase. 168
Changes during fasting in the activity of a specific lysosomal proteinase, fructose-1,6-bisphosphatase converting enzyme. 168
Activation of PKC-beta isoforms mediates HNE-induced MCP-1 release by macrophages 167
Glucose 6-phosphate dehydrogenase activity in membranes of erythrocytes from normal individuals and subjects with Mediterranean G6PD deficiency. 167
Changes in rabbit-liver lysosomes and fructose 1,6-bisphosphatase induced by cold and fasting. 167
Molecular events involved in the activation of calpain from human erythrocytes 166
Characterization of the inactive form of fructose-1,6-bisphosphate aldolase isolated from livers of fasted rabbits. 166
Properties and intracellular localization of calpain activator protein 166
Regulation of calpain activity in rat brain with altered Ca2+ homeostasis 164
Binding of Zn2+ to rabbit muscle fructose 1,6-bisphosphatase and its effect on the catalytic properties. 163
On the mechanism of inhibition of fructose 1,6-bisphosphatase by fructose 2,6-bisphosphate. 162
Interactions of Zn2+ and Mg2+ with rabbit liver fructose 1,6 bisphosphatase. 162
Multiple rat brain calpastatin forms are produced by distinct starting points and alternative splicing of the N-terminal exons. 162
Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process. 162
The role of calpain in the selective increased phosphorylation of the anion-transport protein in red cell of hypertensive subjects. 161
Changes in intracellular localization of calpastatin during calpain activation 161
The calpain-calpastatin system in cystic fibrosis: physiopathological implications 161
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein. 161
"Association of calpastatin with inactive calpain: a novel mechanism to control the activation of the protease?" 161
Changes in intracellular calpastatin localization are mediated by reversible phosphorylation 159
Interaction between Calpain-1 and HSP90: New Insights into the Regulation of Localization and Activity of the Protease. 159
Effects of ethanol metabolism on PKC activity in isolated rat hepatocytes. 158
Age-dependent degradation of calpastatin in kidney of hypertensive rats 157
Extralysosomal protein degradation. 156
Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90. 156
Binding of monoclonal antibody to cathepsin M located on the external surface of rabbit lysosomes. 155
Cytosolic calcium dependent proteinase of human erythrocytes: formation of an enzyme-natural inhibitor complex induced by Ca2+ ions. 155
“In vivo degradation of Nitric-Oxide Synthase isozymes by Calpain is regulated by HSP90” 155
Identification of a novel neutrophil membrane protein involved in modulation of oxidative burst. 154
Antisense oligodeoxynucleotide inhibition of delta protein kinase C expression accelerates induced differentiation of murine erythroleukaemia cells 154
Mechanisms of inactivation of hepatocyte protein kinase C isoforms following acute ethanol treatment 154
Comparative patterns of 'in vitro' oxidative hemolysis of normal and glucose 6-phosphate dehydrogenase (G6PD)-deficient erythrocytes. 154
Inactivation of liver aldolase in fasting rabbits: evidence for the accumulation of two different immunoreactive forms. 153
Biochemical responses in activated human neutrophils mediated by protein kinase C and a Ca2+-requiring proteinase. 153
Changes in activity of fructose-1,6-bisphosphate aldolase in livers of fasted rabbits and accumulation of crossreacting immune material. 152
Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein 152
Decreased level of calpain inhibitor activity in kidney from Milan hypertensive rats. 151
Role of calpain in the regulation of CFTR (cystic fibrosis transmembrane conductance regulator) turnover 151
Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation 150
"Cytosolic levels of calpastatin are regulated by limited proteolysis" 150
Phosphorylation and proteolytic modification of specific cytoskeletal proteins in human neutrophils stimulated by phorbol 12-myristate 13-acetate. 149
Selective Pro-Inflammatory Activation of Astrocytes by High Mobility Group Box 1 Protein Signaling 149
The plasma membrane calcium pump is the preferred calpain substrate within the erythrocyte 148
Role of PKC-delta activity in glutathione-depleted neuroblastoma cells 148
Isolation and characterization of calpain activator protein from bovine brain. 148
Fructose-1, 6-diphosphatase from rabbit liver. 148
Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation. 148
ATP induces the release of a neutral serine proteinase and enhances the production of superoxide anion in membranes from phorbol ester-activated neutrophils. 148
Inactivation of fructose 1,6-bisphosphatase by a lysosomal proteinase is reversed by cystamine. 147
Isovalerylcarnitine is a specific activator of the high calcium requiring calpain forms. 147
Fructose 1,6-bisphosphatase: the role of lysosomal enzymes in the modification of catalytic and structural properties. 147
Cytosolic levels of calpastatin are regulated by limited proteolysis 147
Ethanol-induced effects on expression level, activity and distribution of protein kinase C isoforms in rat liver Golgi apparatus 147
Adaptive modifications in the calpain/calpastatin system in brain cells after persistent alteration in Ca2+ homeostasis 147
Two cytosolic, Ca2+-dependent, neutral proteinases from rabbit liver: purification and properties of the proenzymes. 146
The calpastatin defect in hypertension is possibly due to a specific degradation by calpain. 146
Depletion of protein kinase C induced by an anti HLA class I monoclonal antibody in phytohemagglutinin activated human T cells. 145
Totale 17.240
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Categoria #
all - tutte 95.912
article - articoli 83.931
book - libri 557
conference - conferenze 9.460
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.964
Totale 191.824
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021152 0 0 0 0 0 0 0 0 0 0 0 152
2021/20222.829 66 187 195 313 122 186 209 610 130 291 117 403
2022/20232.879 260 168 27 370 450 563 1 197 526 13 267 37
2023/20241.339 66 181 13 141 172 316 49 51 78 35 73 164
2024/20254.345 233 319 114 269 628 475 368 627 198 162 408 544
2025/20266.200 814 123 310 463 825 676 1.134 278 570 593 236 178
Totale 33.945