IRIS
MELLONI, EDON
 Distribuzione geografica
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Continente #
EU - Europa 29.742
AS - Asia 2.562
NA - Nord America 2.108
SA - Sud America 225
Continente sconosciuto - Info sul continente non disponibili 167
AF - Africa 45
OC - Oceania 21
Totale 34.870
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Nazione #
IT - Italia 29.277
US - Stati Uniti d'America 1.954
SG - Singapore 1.159
CN - Cina 667
VN - Vietnam 395
FR - Francia 238
BR - Brasile 135
BD - Bangladesh 116
HK - Hong Kong 67
CA - Canada 60
DE - Germania 50
AR - Argentina 42
JP - Giappone 34
FI - Finlandia 32
GB - Regno Unito 28
MX - Messico 27
AU - Australia 21
IN - India 20
CH - Svizzera 19
JM - Giamaica 19
CO - Colombia 16
NL - Olanda 16
ID - Indonesia 14
IQ - Iraq 13
ES - Italia 12
TR - Turchia 10
ZA - Sudafrica 10
AE - Emirati Arabi Uniti 9
CR - Costa Rica 9
HN - Honduras 9
EC - Ecuador 8
PH - Filippine 8
GT - Guatemala 7
IE - Irlanda 7
UA - Ucraina 7
VE - Venezuela 7
KR - Corea 6
MA - Marocco 6
PL - Polonia 6
RU - Federazione Russa 6
SA - Arabia Saudita 6
TT - Trinidad e Tobago 6
JO - Giordania 5
NI - Nicaragua 5
PE - Perù 5
RO - Romania 5
TW - Taiwan 5
UZ - Uzbekistan 5
BE - Belgio 4
CL - Cile 4
DZ - Algeria 4
EG - Egitto 4
KE - Kenya 4
KZ - Kazakistan 4
RS - Serbia 4
SE - Svezia 4
TH - Thailandia 4
BA - Bosnia-Erzegovina 3
BO - Bolivia 3
CZ - Repubblica Ceca 3
PR - Porto Rico 3
SK - Slovacchia (Repubblica Slovacca) 3
AL - Albania 2
AO - Angola 2
CY - Cipro 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
IL - Israele 2
LT - Lituania 2
MT - Malta 2
MY - Malesia 2
NG - Nigeria 2
NO - Norvegia 2
PK - Pakistan 2
PY - Paraguay 2
SC - Seychelles 2
SN - Senegal 2
TG - Togo 2
TN - Tunisia 2
UY - Uruguay 2
AT - Austria 1
AW - Aruba 1
AZ - Azerbaigian 1
BB - Barbados 1
BG - Bulgaria 1
BM - Bermuda 1
BW - Botswana 1
BY - Bielorussia 1
BZ - Belize 1
CG - Congo 1
CI - Costa d'Avorio 1
EE - Estonia 1
GF - Guiana Francese 1
GR - Grecia 1
HU - Ungheria 1
IR - Iran 1
KW - Kuwait 1
LB - Libano 1
LK - Sri Lanka 1
Totale 34.696
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Città #
Genova 19.018
Genoa 5.922
Rapallo 2.408
Vado Ligure 1.761
San Jose 624
Singapore 563
Lauterbourg 218
Ashburn 173
Ho Chi Minh City 114
New York 108
Beijing 94
Hanoi 71
Hong Kong 59
Santa Clara 56
Frankfurt am Main 44
Helsinki 32
Tokyo 32
Los Angeles 30
Bordighera 29
Council Bluffs 24
Da Nang 21
Haiphong 21
Chicago 19
Zurich 19
Mexico City 18
Buffalo 17
Tianjin 17
Phoenix 15
Montreal 14
Amsterdam 13
Dallas 13
Kingston 13
Rome 13
São Paulo 13
Houston 11
Milan 11
Toronto 11
Atlanta 10
Brooklyn 10
Naples 10
Washington 10
Jacksonville 9
Madrid 9
San Francisco 9
Des Moines 8
Orem 8
Baghdad 7
Dublin 7
Guatemala City 7
London 7
Philadelphia 7
Rio de Janeiro 7
San José 7
Biên Hòa 6
Hải Dương 6
Quảng Ngãi 6
Sydney 6
Abu Dhabi 5
Bari 5
Cardiff 5
City of London 5
Cleveland 5
Dhaka 5
Guangzhou 5
Istanbul 5
Jeddah 5
Johannesburg 5
Las Vegas 5
Miami 5
Mumbai 5
Newark 5
Paris 5
Sumter 5
Tashkent 5
The Bronx 5
Warsaw 5
Wuhan 5
Acalanes Ridge 4
Amman 4
Belgrade 4
Bogotá 4
Cairo 4
Charlotte 4
Detroit 4
Durham 4
Edmonton 4
Iowa City 4
Managua 4
Marseille 4
Melbourne 4
New Orleans 4
Nha Trang 4
Ninh Bình 4
Omaha 4
Palermo 4
Pittsburgh 4
Queens 4
Shanghai 4
Springfield 4
Tegucigalpa 4
Totale 31.987
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Nome #
Activation of calpain 1 and protein kinase C alpha promotes a constitutive expression and release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 321
"Intracellular calpastatin proteolysis: a salvage mechanism or a prelude to cell damage?" 267
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 250
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 250
Evidence for alteration of calpain/calpastatin system in PBMC of cystic fibrosis patients 231
Activation of Ca2+-dependent proteolysis in skeletal muscle and heart in cancer cachexia. 219
Clinical Severity of β-thalassaemia/Hb E Disease Is Associated with Differential Activities of the Calpain-Calpastatin Proteolytic System. 216
Role of the calpain-calpastatin system in the density-dependent growth arrest 215
A vincristine-resistant murine erythroleukemia cell line secretes a differentiation enhancing factor. 213
Glycine taken up through GLYT1 and GLYT2 heterotransporters into glutamatergic axon terminals of mouse spinal cord elicits release of glutamate by homotransporter reversal and through anion channels 212
Glia re-sealed particles freshly prepared from adult rat brain are competent for exocytotic release of glutamate 210
Acyl-CoA-binding protein is a potent m-calpain activator 210
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain. 209
Role of the regulatory domain of calpastatin in the autoproteolytic activation of calpain 204
Autolysis of human erythrocytes calpain produces two active enzyme forms with different cell localization 201
Calpain inhibition promotes the rescue of F(508)del-CFTR in PBMC from cystic fibrosis patients. 201
Modulation of the calpain autoproteolysis by calpastatin and phospholipids 198
Characterization of a new p94-like calpain form in human lymphocytes 198
Characterization of the calpain/calpastatin system in human hemopoietic cell lines 197
Effect of extremely low frequency magnetic fields on calpain activation 193
Cell protection from Ca2+-overloading by bioactive molecules extracted from olive pomace 193
Activation by hemoglobin of the Ca2+-requiring neutral proteinase of human erythrocytes: structural requirements. 192
Activation of neutrophil calpain following its translocation to the plasma membrane induced by phorbol ester or fMet-Leu-Phe.. 191
Axonal damage and demyelination in long-term dorsal root ganglia cultures from a rat model of Charcot-Marie-Tooth type 1A disease 191
Conformational changes of calpain from human erythrocytes in the presence of Ca2+. 190
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 190
Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex. 190
Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase. 188
Involvement of exon 6-mediated calpastatin intracellular movements in the modulation of calpain activation. 187
Pathological role of the calpain/calpastatin system in cystic fibrosis 184
Carbon tetrachloride-induced inhibition of protein kinase C in isolated rat hepatocytes. 183
Degradation of CFTR-generated protein clusters by calpain: A physiological or a pathological role? 181
Inactivation of hepatocyte protein kinase C by carbon tetrachloride: involvement of drug's metabolic activation and prooxidant effect. 180
Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli 180
The calpain-calpastatin system in mammalian cells: properties and possible functions 179
IGF-I induced rapid recruitment of integrin β1 to lipid rafts is Caveolin-1 dependent 179
The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes 176
Activation of NADPH oxidase and phosphorylation of membrane proteins in human neutrophils: coordinate inhibition by a surface antigen-directed monoclonal antibody. 176
Activation of PKC-beta isoforms mediates HNE-induced MCP-1 release by macrophages 175
Changes during fasting in the activity of a specific lysosomal proteinase, fructose-1,6-bisphosphatase converting enzyme. 174
Characterization of the defective calpain-endogenous calpain inhibitor system in erythrocytes from Milan hypertensive rats. 173
Characterization of the calpastatin defect in erythrocytes from patients with essential hypertension. 172
A dual role for the Ca2+-requiring proteinase in the degradation of hemoglobin by erythrocyte membrane proteinases. 172
Glucose 6-phosphate dehydrogenase activity in membranes of erythrocytes from normal individuals and subjects with Mediterranean G6PD deficiency. 172
Changes in rabbit-liver lysosomes and fructose 1,6-bisphosphatase induced by cold and fasting. 172
Changes in calpastatin localization and expression during calpain activation: a new mechanism for the regulation of intracellular Ca(2+)-dependent proteolysis. 171
Regulation of calpain activity in rat brain with altered Ca2+ homeostasis 171
Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase. 171
Characterization of the inactive form of fructose-1,6-bisphosphate aldolase isolated from livers of fasted rabbits. 171
Properties and intracellular localization of calpain activator protein 171
Cathepsin M: a lysosomal proteinase with aldolase-inactivating activity 170
Changes in intracellular localization of calpastatin during calpain activation 168
Multiple rat brain calpastatin forms are produced by distinct starting points and alternative splicing of the N-terminal exons. 168
Binding of Zn2+ to rabbit muscle fructose 1,6-bisphosphatase and its effect on the catalytic properties. 167
Interactions of Zn2+ and Mg2+ with rabbit liver fructose 1,6 bisphosphatase. 167
Molecular events involved in the activation of calpain from human erythrocytes 166
On the mechanism of inhibition of fructose 1,6-bisphosphatase by fructose 2,6-bisphosphate. 166
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein. 165
The role of calpain in the selective increased phosphorylation of the anion-transport protein in red cell of hypertensive subjects. 164
"Association of calpastatin with inactive calpain: a novel mechanism to control the activation of the protease?" 164
Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process. 164
Effects of ethanol metabolism on PKC activity in isolated rat hepatocytes. 164
The calpain-calpastatin system in cystic fibrosis: physiopathological implications 163
Interaction between Calpain-1 and HSP90: New Insights into the Regulation of Localization and Activity of the Protease. 162
Antisense oligodeoxynucleotide inhibition of delta protein kinase C expression accelerates induced differentiation of murine erythroleukaemia cells 161
Cytosolic calcium dependent proteinase of human erythrocytes: formation of an enzyme-natural inhibitor complex induced by Ca2+ ions. 161
Changes in intracellular calpastatin localization are mediated by reversible phosphorylation 161
Extralysosomal protein degradation. 159
Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90. 159
Binding of monoclonal antibody to cathepsin M located on the external surface of rabbit lysosomes. 159
Comparative patterns of 'in vitro' oxidative hemolysis of normal and glucose 6-phosphate dehydrogenase (G6PD)-deficient erythrocytes. 159
Age-dependent degradation of calpastatin in kidney of hypertensive rats 159
“In vivo degradation of Nitric-Oxide Synthase isozymes by Calpain is regulated by HSP90” 159
Identification of a novel neutrophil membrane protein involved in modulation of oxidative burst. 157
Inactivation of fructose 1,6-bisphosphatase by a lysosomal proteinase is reversed by cystamine. 157
Biochemical responses in activated human neutrophils mediated by protein kinase C and a Ca2+-requiring proteinase. 157
Mechanisms of inactivation of hepatocyte protein kinase C isoforms following acute ethanol treatment 156
Inactivation of liver aldolase in fasting rabbits: evidence for the accumulation of two different immunoreactive forms. 156
Selective Pro-Inflammatory Activation of Astrocytes by High Mobility Group Box 1 Protein Signaling 156
Changes in activity of fructose-1,6-bisphosphate aldolase in livers of fasted rabbits and accumulation of crossreacting immune material. 156
Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation. 155
Ethanol-induced effects on expression level, activity and distribution of protein kinase C isoforms in rat liver Golgi apparatus 155
Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation 154
Decreased level of calpain inhibitor activity in kidney from Milan hypertensive rats. 154
Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein 154
Adaptive modifications in the calpain/calpastatin system in brain cells after persistent alteration in Ca2+ homeostasis 154
Cytosolic levels of calpastatin are regulated by limited proteolysis 153
"Cytosolic levels of calpastatin are regulated by limited proteolysis" 153
Role of calpain in the regulation of CFTR (cystic fibrosis transmembrane conductance regulator) turnover 153
The plasma membrane calcium pump is the preferred calpain substrate within the erythrocyte 152
Phosphorylation and proteolytic modification of specific cytoskeletal proteins in human neutrophils stimulated by phorbol 12-myristate 13-acetate. 152
Fructose 1,6-bisphosphatase: the role of lysosomal enzymes in the modification of catalytic and structural properties. 151
ATP induces the release of a neutral serine proteinase and enhances the production of superoxide anion in membranes from phorbol ester-activated neutrophils. 151
Isolation and characterization of calpain activator protein from bovine brain. 150
Fructose 1,6-bisphosphatase: properties of the neutral enzyme and its modification by proteolytic enzymes. 150
The calpastatin defect in hypertension is possibly due to a specific degradation by calpain. 150
Role of PKC-delta activity in glutathione-depleted neuroblastoma cells 149
Isovalerylcarnitine is a specific activator of the high calcium requiring calpain forms. 149
Two cytosolic, Ca2+-dependent, neutral proteinases from rabbit liver: purification and properties of the proenzymes. 149
Role of calpain-1 in the early phase of experimental ALS 149
Totale 17.697
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Categoria #
all - tutte 100.618
article - articoli 88.071
book - libri 579
conference - conferenze 9.894
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 2.074
Totale 201.236
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.763 0 187 195 313 122 186 209 610 130 291 117 403
2022/20232.879 260 168 27 370 450 563 1 197 526 13 267 37
2023/20241.339 66 181 13 141 172 316 49 51 78 35 73 164
2024/20254.345 233 319 114 269 628 475 368 627 198 162 408 544
2025/20266.378 814 123 310 463 825 676 1.134 278 570 593 236 356
2026/2027747 729 18 0 0 0 0 0 0 0 0 0 0
Totale 34.870