IRIS
SCHENONE, SILVIA
 Distribuzione geografica
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Continente #
EU - Europa 30.579
AS - Asia 3.735
NA - Nord America 2.146
SA - Sud America 272
AF - Africa 45
OC - Oceania 3
Totale 36.780
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Nazione #
IT - Italia 29.991
US - Stati Uniti d'America 2.040
SG - Singapore 1.598
CN - Cina 1.006
VN - Vietnam 590
FR - Francia 267
HK - Hong Kong 180
BR - Brasile 162
JP - Giappone 87
DE - Germania 83
BD - Bangladesh 69
FI - Finlandia 64
AR - Argentina 50
MX - Messico 46
GB - Regno Unito 40
CA - Canada 34
IN - India 33
NL - Olanda 26
ID - Indonesia 25
ES - Italia 22
TW - Taiwan 19
CH - Svizzera 15
KR - Corea 14
EC - Ecuador 13
PH - Filippine 13
VE - Venezuela 13
IQ - Iraq 12
CL - Cile 11
RU - Federazione Russa 11
SA - Arabia Saudita 11
TR - Turchia 10
IE - Irlanda 9
TH - Thailandia 9
CO - Colombia 8
PK - Pakistan 8
PL - Polonia 8
DZ - Algeria 7
JM - Giamaica 7
JO - Giordania 7
PY - Paraguay 7
ZA - Sudafrica 7
AZ - Azerbaigian 6
ET - Etiopia 6
GR - Grecia 6
KE - Kenya 6
NP - Nepal 6
PT - Portogallo 6
UA - Ucraina 5
HR - Croazia 4
MY - Malesia 4
PA - Panama 4
SE - Svezia 4
TN - Tunisia 4
UZ - Uzbekistan 4
AM - Armenia 3
AU - Australia 3
BY - Bielorussia 3
EG - Egitto 3
IL - Israele 3
MA - Marocco 3
PE - Perù 3
SN - Senegal 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
AT - Austria 2
BO - Bolivia 2
CY - Cipro 2
CZ - Repubblica Ceca 2
GT - Guatemala 2
HN - Honduras 2
HU - Ungheria 2
IR - Iran 2
KG - Kirghizistan 2
KH - Cambogia 2
KW - Kuwait 2
PR - Porto Rico 2
SI - Slovenia 2
UY - Uruguay 2
BB - Barbados 1
BF - Burkina Faso 1
BG - Bulgaria 1
BH - Bahrain 1
BZ - Belize 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
CU - Cuba 1
DO - Repubblica Dominicana 1
EE - Estonia 1
GY - Guiana 1
KZ - Kazakistan 1
LC - Santa Lucia 1
LU - Lussemburgo 1
LV - Lettonia 1
LY - Libia 1
MG - Madagascar 1
MM - Myanmar 1
MN - Mongolia 1
MU - Mauritius 1
NE - Niger 1
NI - Nicaragua 1
Totale 36.775
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Città #
Genova 17.675
Genoa 7.569
Rapallo 2.357
Vado Ligure 2.117
Singapore 804
San Jose 701
Ashburn 249
Lauterbourg 234
Beijing 168
Council Bluffs 167
Ho Chi Minh City 163
Hong Kong 147
New York 134
Hanoi 130
Frankfurt am Main 76
Tokyo 75
Helsinki 62
Milan 50
Santa Clara 50
Los Angeles 44
Bordighera 32
Haiphong 32
Mexico City 30
Da Nang 27
Boardman 25
São Paulo 23
Tianjin 23
Paris 22
Amsterdam 21
Chicago 21
Rome 19
Dallas 17
Biên Hòa 15
Naples 15
Orem 15
Buffalo 13
Montreal 11
Zurich 11
Denver 10
Jakarta 10
Memphis 10
St Louis 10
Atlanta 9
City of London 9
Dublin 9
Buenos Aires 8
Can Tho 8
Jeddah 8
Phoenix 8
San Francisco 8
Seattle 8
Amman 7
Cardiff 7
Des Moines 7
Phủ Lý 7
Santiago 7
Addis Ababa 6
Athens 6
Baghdad 6
Baku 6
Brooklyn 6
Cagliari 6
Guangzhou 6
Guayaquil 6
Hải Dương 6
London 6
Madrid 6
Quảng Ngãi 6
Thái Bình 6
Điện Bàn 6
Asunción 5
Bắc Ninh 5
Campinas 5
Caracas 5
Curitiba 5
Dhaka 5
Houston 5
Johannesburg 5
Nairobi 5
Nha Trang 5
Pisa 5
Quito 5
Shanghai 5
Taipei 5
Turin 5
Vĩnh Long 5
Warsaw 5
Washington 5
Basingstoke 4
Belo Horizonte 4
Brescia 4
Chennai 4
Detroit 4
Dobong-gu 4
Draper 4
Hangzhou 4
New Delhi 4
Ninh Bình 4
Palermo 4
Panama City 4
Totale 33.716
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Nome #
Antiproliferative and pro-apoptotic effects afforded by novel Src-kinase inhibitors in human neuroblastoma cells. 205
Analogs, formulations and derivatives of imatinib: A patent review 201
SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW 4-AMINO-PYRAZOLO[3,4-d]PYRIMIDINES AS POTENTIAL SRC KINASE INHIBITORS 198
A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors. 196
Indolyl-pyrrolone as a new scaffold for Pim1 inhibitors 196
The search for a common structural moiety among selected pharmacological correctors of the mutant CFTR chloride channel. 193
ATP-competitive inhibitors of mTOR: an update. 192
1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors 192
Affinity prediction on A1 adenosine receptor agonists: the chemometric approach 191
N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds. 190
Molecular characterization of c-Abl/c-Src kinase inhibitors targeted against murine tumour progenitor cells that express stem cell markers. 187
Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives 187
Click Chemistry, A Potent Tool in Medicinal Sciences 185
An update on dual Src/Abl inhibitors 183
4-Amine-substituted derivatives of pyrazolo[3,4-d]pyrimidine and their preparation, pharmaceutical compositions, and use as antitumor agents 183
A cascade screening approach for the identification of Bcr-Abl myristate pocket binders active against wild type and T315I mutant 182
1-Acyl-, 3-acyl- and 1,3-diacyl-3-furfuryl-1-phenylthioureas with platelet antiaggregating and other activities. 181
State-of-the-art Review on the Antiparasitic Activity of Benzimidazole-based Derivatives: Facing Malaria, Leishmaniasis, and Trypanosomiasis 180
Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against Neuroblastoma. 180
Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma 180
Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors 179
Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells. 177
3-Arylsulphonyl-5-arylamino-1,3,4-thiadiazol-2(3H)ones as antiinflammatory and analgesic agents 177
Synthesis and biological evaluation of neutrophilic inflammation inhibitors 177
2-Aryl-3-phenylamino-4,5-dihydro-2h-benz[g]indazoles with analgesic activity 176
Fyn kinase in brain diseases and cancer: the search for inhibitors. 176
Bcr-Abl tyrosine kinase inhibitors: A patent review 174
"One-pot" synthesis of N-acyl-N-phenylcarbamate derivatives endowed with anti-HIV and/or antiproliferative activities 172
A chemometric approach to predict A1 agonist effect of adenosine analogues 172
Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines 170
Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line 163
3,3-disubstituted 1-acyl-1-phenylthioureas with platelet antiaggregating and other activities 162
The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme 162
Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis 162
Last findings on dual inhibitors of abl and SRC tyrosine-kinases. 157
2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole derivatives: New potent inhibitors of fMLP-induced neutrophil chemotaxis 156
Derivati dell'1,3-benzodiossolo, potenziali inibitori delle PDE5 153
3-Cyano-4,6-diphenyl-pyridine amino acid derivatives active as influenza A polymerase inhibitors 153
Synthetic SRC-kinase domain inhibitors and their structural requirements 151
2-aryl-3-phenylamino-4,5-dihydro-2H-benz[g]indazoles with antiarrhythmic and local anaesthetic activities 151
2-Amino/Azido/Hydrazino-5-alkoxy-5H-[1]benzopyrano[4,3-d]pyrimidines: Synthesis and Pharmacological Evaluation 151
Recent Studies on Ponatinib in Cancers Other Than Chronic Myeloid Leukemia 151
A combination of docking/dynamics simulations and pharmacophoric modeling to discover new dual c-Src/Abl kinase inhibitors. 150
2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors. 150
3-(Arylamino)-6,7-dihydro-6-methylpyrano[4,3-c]pyrazol-4(1H or 2H)-ones with antipyretic, analgesic, antiarrhythmic, hypotensive and other activities. 150
Matrine in association with FD‑2 stimulates F508del‑cystic fibrosis transmembrane conductance regulator activity in the presence of corrector VX809 150
New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation 150
Antiinflammatory agents: new series of N-substituted amino acids with complex pyrimidine structures endowed with antiphlogistic activity 150
Synthesis, molecular modeling studies and pharmacological activity of selective A1 receptor antagonists 149
Src kinase inhibitors: an update on patented compounds 149
F508del-CFTR rescue: a matter of cell stress response. 149
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors. 149
N-Acyl-N-phenyl ureas of piperidine and substituted piperidines endowed with antiinflammatory and antiproliferative activities 149
A1 receptors ligands: past, present and future trends. 148
Pyrazolo-pyrimidine-derived c-Src inhibitor reduces angiogenesis and survival of squamous carcinoma cells by suppressing vascular endothelial growth factor production and signaling. 147
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents. 147
SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: A new route of epigenomic regulation 147
Synthesis and pharmacological evaluation of 5H-[1]benzopyrano[4,3-d]pyrimidines effective as antiplatelet/analgesic agents 147
Biologically driven synthesis of pyrazolo[3,4-d]pyrimidines as protein kinase inhibitors: an old scaffold as a new tool for medicinal chemistry and chemical biology studies 146
Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors 146
Water Solubility Enhancement of Pyrazolo[3,4-d]pyrimidine Derivatives via Miniaturized Polymer–Drug Microarrays 146
Phenylhydrazones as Correctors of a Mutant Cystic Fibrosis Transmembrane Conductance Regulator 145
4-Amino-pyrazolo[3,4-d]pyrimidines with antiproliferative activity on osteosarcoma cell line SaOS-2 144
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment 144
An Update on JAK Inhibitors 144
Pyrrolo[2,3-d]pyrimidines as kinase inhibitors 143
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data. 142
Unprecedented one-pot stereoselective synthesis of Knoevenagel-type derivatives via in situ condensation of N-methyleniminium salts of ethylenethiourea and ethyleneurea with active methylene reagents 142
Hit identification and biological evaluation of anticancer pyrazolopyrimidines endowed with anti-inflammatory activity 142
2-Aryl-6-methyl-3-phenylamino-6,7-dihydropyrano[4,3-c]pyrazol-4(2H)-ones with analgesic activity. 142
Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant. 142
Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction 142
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation. 142
Synthesis, Biological Activity, and ADME Properties of Novel S-DABOs/N-DABOs as HIV Reverse Transcriptase Inhibitors 141
New halogenated 4-aminopyrazolo[3,4-b]pyridines A1 adenosine receptor ligands 140
New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells. 140
Insight into the allosteric inhibition of Abl kinase 140
Exploring the molecular basis of selectivity in A1 adenosine receptors antagonist: a case study 140
New pyrazolo[3,4-d]pyrimidine SRC inhibitors induce apoptosis in mesothelioma cell lines through p27 nuclear stabilization 139
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 138
A Pyrazolo[3,4-d]pyrimidine compound inhibits Fyn phosphorylation and induces apoptosis in natural killer cell leukemia 138
Exploring SAR of a new generation of pyrazolo[3,4-d]pyrimidines as Fyn tyrosine kinase inhibitors 138
Structure-based Design, Parallel Synthesis, SAR and Molecular Modelling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea Derivatives. 137
New SRC/ABL inhibitors for chronic myeloid leukemia therapy show selectivity for T315I ABL mutant CD34(+) cells. 137
Antitumor activity of new pyrazolo[3,4-d]pyrimidine SRC kinase inhibitors in Burkitt lymphoma cell lines and its enhancement by WEE1 inhibition. 137
Pyrazolo[3,4-d]pyrimidines c-Src inhibitors reduce epidermal growth factor-induced migration in prostate cancer cells. 137
Antiangiogenic agents: an update on small molecule VEGFR inhibitors 136
2,3-Dihydro-1H-imidazo[1,2-b]pyrazole derivatives as potential neutrophils functions inhibitors 136
Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model 136
Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells 136
Synthesis of new piperazine-pyridazinone derivatives and their binding affinity toward alpha1-, alpha2-adrenergic and 5-HT1A serotoninergic receptors. 136
Preparation of new 5-aroylamino substituted 3-nicotinoyl/isonicotinoyl-1,3,4-thiadiazol-2(3H)-ones with anti-inflammatory activity 135
Allosteric inhibitors of Bcr-Abl: towards novel myristate-pocket binders. 135
5-alkoxy-2-hydrazino and 5-methoxy-2-amino-5H-[1]benzopyrano[4,3-d]pyrimidines: synthesis and pharmacological activity 135
Synthesis and pharmacological evaluation of 2,5-Cycloamino-5H[1]benzopyrano[4,3-d]pyrimidines endowed with in vitro antiplatelet activity 135
Synthesis of a small library of potential SGK1 inihibitors 135
Small molecules ATP-competitive inhibitors of FLT3: a chemical overview. 134
Using insights into Pim1 structure to design new anticancer drugs. 134
CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction. 133
Substituted pyrazolo[3,4-b]pyridines as potent A1 adenosine antagonists: synthesis, biological evaluation, and development of an A1 bovine receptor model. 133
Totale 15.628
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Categoria #
all - tutte 116.307
article - articoli 87.261
book - libri 0
conference - conferenze 25.556
curatela - curatele 0
other - altro 0
patent - brevetti 2.426
selected - selezionate 0
volume - volumi 1.064
Totale 232.614
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021174 0 0 0 0 0 0 0 0 0 0 0 174
2021/20223.178 59 196 291 409 95 221 233 766 158 222 135 393
2022/20232.864 290 171 31 321 450 512 0 206 527 25 286 45
2023/20241.626 70 265 47 186 121 193 98 62 103 52 133 296
2024/20254.951 87 384 173 327 777 581 432 679 181 288 415 627
2025/20269.846 983 254 933 770 1.265 1.022 1.594 579 705 1.060 515 166
Totale 37.375