IRIS
SCHENONE, SILVIA
 Distribuzione geografica
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Continente #
EU - Europa 30.716
AS - Asia 3.892
NA - Nord America 3.117
Continente sconosciuto - Info sul continente non disponibili 595
SA - Sud America 312
AF - Africa 48
OC - Oceania 3
Totale 38.683
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Nazione #
IT - Italia 30.107
US - Stati Uniti d'America 2.948
SG - Singapore 1.601
CN - Cina 1.017
VN - Vietnam 595
FR - Francia 272
BD - Bangladesh 187
HK - Hong Kong 182
BR - Brasile 180
JP - Giappone 87
DE - Germania 84
FI - Finlandia 64
CA - Canada 57
AR - Argentina 55
MX - Messico 46
GB - Regno Unito 40
IN - India 36
ES - Italia 28
ID - Indonesia 26
NL - Olanda 26
JM - Giamaica 23
TW - Taiwan 19
EC - Ecuador 18
CH - Svizzera 15
CL - Cile 14
KR - Corea 14
PK - Pakistan 14
VE - Venezuela 14
CO - Colombia 13
PH - Filippine 13
IQ - Iraq 12
RU - Federazione Russa 11
SA - Arabia Saudita 11
PL - Polonia 10
TR - Turchia 10
IE - Irlanda 9
TH - Thailandia 9
AE - Emirati Arabi Uniti 8
PY - Paraguay 8
CR - Costa Rica 7
DZ - Algeria 7
GT - Guatemala 7
JO - Giordania 7
PT - Portogallo 7
ZA - Sudafrica 7
AZ - Azerbaigian 6
ET - Etiopia 6
GR - Grecia 6
KE - Kenya 6
MY - Malesia 6
NP - Nepal 6
AT - Austria 5
PA - Panama 5
SE - Svezia 5
UA - Ucraina 5
HR - Croazia 4
PE - Perù 4
PR - Porto Rico 4
TN - Tunisia 4
UZ - Uzbekistan 4
AM - Armenia 3
AU - Australia 3
BO - Bolivia 3
BY - Bielorussia 3
DO - Repubblica Dominicana 3
EG - Egitto 3
HN - Honduras 3
IL - Israele 3
MA - Marocco 3
SN - Senegal 3
SV - El Salvador 3
TT - Trinidad e Tobago 3
AL - Albania 2
CI - Costa d'Avorio 2
CY - Cipro 2
CZ - Repubblica Ceca 2
HU - Ungheria 2
IR - Iran 2
KG - Kirghizistan 2
KH - Cambogia 2
KW - Kuwait 2
LC - Santa Lucia 2
NI - Nicaragua 2
RO - Romania 2
SI - Slovenia 2
UY - Uruguay 2
BB - Barbados 1
BF - Burkina Faso 1
BG - Bulgaria 1
BH - Bahrain 1
BZ - Belize 1
CU - Cuba 1
DK - Danimarca 1
EE - Estonia 1
GY - Guiana 1
KZ - Kazakistan 1
LU - Lussemburgo 1
LV - Lettonia 1
LY - Libia 1
MG - Madagascar 1
Totale 38.079
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Città #
Genova 17.675
Genoa 7.586
Rapallo 2.357
Vado Ligure 2.117
San Jose 849
Singapore 804
Ashburn 334
Lauterbourg 234
Beijing 175
Council Bluffs 167
Ho Chi Minh City 164
Hong Kong 147
New York 144
Hanoi 134
Frankfurt am Main 76
Tokyo 75
Santa Clara 65
Helsinki 62
Milan 60
Los Angeles 58
Chicago 39
Bordighera 33
Haiphong 32
Mexico City 30
Rome 29
Da Nang 27
Boardman 25
São Paulo 24
Tianjin 23
Amsterdam 22
Dallas 22
Naples 22
Paris 22
Buffalo 21
Atlanta 20
Houston 16
Biên Hòa 15
Orem 15
Brooklyn 14
Kingston 14
Montreal 14
Seattle 13
Phoenix 12
St Louis 12
Denver 11
Memphis 11
Zurich 11
Cagliari 10
Jakarta 10
Las Vegas 10
Miami 10
Philadelphia 10
San Francisco 10
Buenos Aires 9
City of London 9
Dublin 9
Santiago 9
Can Tho 8
Jeddah 8
Karachi 8
Montgomery 8
Palermo 8
Washington 8
Amman 7
Baltimore 7
Cardiff 7
Des Moines 7
Florence 7
Guatemala City 7
Guayaquil 7
London 7
Madrid 7
Phủ Lý 7
Queens 7
Quito 7
Turin 7
Addis Ababa 6
Athens 6
Augusta 6
Baghdad 6
Baku 6
Columbus 6
Davenport 6
Detroit 6
Dhaka 6
Guangzhou 6
Hải Dương 6
Louisville 6
Milwaukee 6
Newark 6
Quảng Ngãi 6
San José 6
Thái Bình 6
Điện Bàn 6
Asunción 5
Bogotá 5
Boston 5
Bắc Ninh 5
Campinas 5
Caracas 5
Totale 34.205
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Nome #
Analogs, formulations and derivatives of imatinib: A patent review 207
Antiproliferative and pro-apoptotic effects afforded by novel Src-kinase inhibitors in human neuroblastoma cells. 206
SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW 4-AMINO-PYRAZOLO[3,4-d]PYRIMIDINES AS POTENTIAL SRC KINASE INHIBITORS 204
A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors. 203
Indolyl-pyrrolone as a new scaffold for Pim1 inhibitors 199
1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors 197
N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds. 196
The search for a common structural moiety among selected pharmacological correctors of the mutant CFTR chloride channel. 196
Affinity prediction on A1 adenosine receptor agonists: the chemometric approach 195
ATP-competitive inhibitors of mTOR: an update. 195
Molecular characterization of c-Abl/c-Src kinase inhibitors targeted against murine tumour progenitor cells that express stem cell markers. 193
Click Chemistry, A Potent Tool in Medicinal Sciences 192
Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives 192
Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors 188
An update on dual Src/Abl inhibitors 188
4-Amine-substituted derivatives of pyrazolo[3,4-d]pyrimidine and their preparation, pharmaceutical compositions, and use as antitumor agents 187
Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma 186
1-Acyl-, 3-acyl- and 1,3-diacyl-3-furfuryl-1-phenylthioureas with platelet antiaggregating and other activities. 185
A cascade screening approach for the identification of Bcr-Abl myristate pocket binders active against wild type and T315I mutant 185
Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against Neuroblastoma. 184
Synthesis and biological evaluation of neutrophilic inflammation inhibitors 184
3-Arylsulphonyl-5-arylamino-1,3,4-thiadiazol-2(3H)ones as antiinflammatory and analgesic agents 182
State-of-the-art Review on the Antiparasitic Activity of Benzimidazole-based Derivatives: Facing Malaria, Leishmaniasis, and Trypanosomiasis 181
Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells. 180
Bcr-Abl tyrosine kinase inhibitors: A patent review 180
2-Aryl-3-phenylamino-4,5-dihydro-2h-benz[g]indazoles with analgesic activity 180
Fyn kinase in brain diseases and cancer: the search for inhibitors. 179
A chemometric approach to predict A1 agonist effect of adenosine analogues 177
Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines 175
"One-pot" synthesis of N-acyl-N-phenylcarbamate derivatives endowed with anti-HIV and/or antiproliferative activities 174
3,3-disubstituted 1-acyl-1-phenylthioureas with platelet antiaggregating and other activities 167
Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line 166
The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme 165
Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis 165
2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole derivatives: New potent inhibitors of fMLP-induced neutrophil chemotaxis 163
A combination of docking/dynamics simulations and pharmacophoric modeling to discover new dual c-Src/Abl kinase inhibitors. 161
3-Cyano-4,6-diphenyl-pyridine amino acid derivatives active as influenza A polymerase inhibitors 160
2-Amino/Azido/Hydrazino-5-alkoxy-5H-[1]benzopyrano[4,3-d]pyrimidines: Synthesis and Pharmacological Evaluation 158
Last findings on dual inhibitors of abl and SRC tyrosine-kinases. 158
Derivati dell'1,3-benzodiossolo, potenziali inibitori delle PDE5 157
Src kinase inhibitors: an update on patented compounds 156
2-aryl-3-phenylamino-4,5-dihydro-2H-benz[g]indazoles with antiarrhythmic and local anaesthetic activities 155
Matrine in association with FD‑2 stimulates F508del‑cystic fibrosis transmembrane conductance regulator activity in the presence of corrector VX809 155
A1 receptors ligands: past, present and future trends. 154
F508del-CFTR rescue: a matter of cell stress response. 154
N-Acyl-N-phenyl ureas of piperidine and substituted piperidines endowed with antiinflammatory and antiproliferative activities 154
Synthesis and pharmacological evaluation of 5H-[1]benzopyrano[4,3-d]pyrimidines effective as antiplatelet/analgesic agents 154
Water Solubility Enhancement of Pyrazolo[3,4-d]pyrimidine Derivatives via Miniaturized Polymer–Drug Microarrays 154
New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation 154
Recent Studies on Ponatinib in Cancers Other Than Chronic Myeloid Leukemia 154
Synthetic SRC-kinase domain inhibitors and their structural requirements 153
2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors. 153
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents. 153
Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors 153
Antiinflammatory agents: new series of N-substituted amino acids with complex pyrimidine structures endowed with antiphlogistic activity 153
3-(Arylamino)-6,7-dihydro-6-methylpyrano[4,3-c]pyrazol-4(1H or 2H)-ones with antipyretic, analgesic, antiarrhythmic, hypotensive and other activities. 152
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors. 152
Synthesis, molecular modeling studies and pharmacological activity of selective A1 receptor antagonists 151
Biologically driven synthesis of pyrazolo[3,4-d]pyrimidines as protein kinase inhibitors: an old scaffold as a new tool for medicinal chemistry and chemical biology studies 151
SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: A new route of epigenomic regulation 151
Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction 151
Phenylhydrazones as Correctors of a Mutant Cystic Fibrosis Transmembrane Conductance Regulator 149
Pyrazolo-pyrimidine-derived c-Src inhibitor reduces angiogenesis and survival of squamous carcinoma cells by suppressing vascular endothelial growth factor production and signaling. 148
Hit identification and biological evaluation of anticancer pyrazolopyrimidines endowed with anti-inflammatory activity 148
Pyrrolo[2,3-d]pyrimidines as kinase inhibitors 148
4-Amino-pyrazolo[3,4-d]pyrimidines with antiproliferative activity on osteosarcoma cell line SaOS-2 147
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment 147
An Update on JAK Inhibitors 147
New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells. 146
Insight into the allosteric inhibition of Abl kinase 146
Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant. 146
Exploring SAR of a new generation of pyrazolo[3,4-d]pyrimidines as Fyn tyrosine kinase inhibitors 146
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation. 146
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data. 145
Unprecedented one-pot stereoselective synthesis of Knoevenagel-type derivatives via in situ condensation of N-methyleniminium salts of ethylenethiourea and ethyleneurea with active methylene reagents 144
Synthesis, Biological Activity, and ADME Properties of Novel S-DABOs/N-DABOs as HIV Reverse Transcriptase Inhibitors 144
2-Aryl-6-methyl-3-phenylamino-6,7-dihydropyrano[4,3-c]pyrazol-4(2H)-ones with analgesic activity. 144
New pyrazolo[3,4-d]pyrimidine SRC inhibitors induce apoptosis in mesothelioma cell lines through p27 nuclear stabilization 144
Synthesis of new piperazine-pyridazinone derivatives and their binding affinity toward alpha1-, alpha2-adrenergic and 5-HT1A serotoninergic receptors. 144
Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells 143
Exploring the molecular basis of selectivity in A1 adenosine receptors antagonist: a case study 143
Structure-based Design, Parallel Synthesis, SAR and Molecular Modelling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea Derivatives. 142
New halogenated 4-aminopyrazolo[3,4-b]pyridines A1 adenosine receptor ligands 142
Antitumor activity of new pyrazolo[3,4-d]pyrimidine SRC kinase inhibitors in Burkitt lymphoma cell lines and its enhancement by WEE1 inhibition. 142
2,3-Dihydro-1H-imidazo[1,2-b]pyrazole derivatives as potential neutrophils functions inhibitors 141
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 141
Synthesis of a small library of potential SGK1 inihibitors 141
Antiangiogenic agents: an update on small molecule VEGFR inhibitors 139
Preparation of new 5-aroylamino substituted 3-nicotinoyl/isonicotinoyl-1,3,4-thiadiazol-2(3H)-ones with anti-inflammatory activity 139
A Pyrazolo[3,4-d]pyrimidine compound inhibits Fyn phosphorylation and induces apoptosis in natural killer cell leukemia 139
3,5-Diphenyl-1H-pyrazole derivatives. XII. N-substituted 4-amino-1-(2-hydroxy- or 2-alkylaminoethyl)-3,5-diphenyl-1H-pyrazoles with local anesthetic, analgesic and platelet antiaggregating activities. 139
New SRC/ABL inhibitors for chronic myeloid leukemia therapy show selectivity for T315I ABL mutant CD34(+) cells. 138
Allosteric inhibitors of Bcr-Abl: towards novel myristate-pocket binders. 138
5-alkoxy-2-hydrazino and 5-methoxy-2-amino-5H-[1]benzopyrano[4,3-d]pyrimidines: synthesis and pharmacological activity 138
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors 138
Small molecules ATP-competitive inhibitors of FLT3: a chemical overview. 137
Substituted pyrazolo[3,4-b]pyridines as potent A1 adenosine antagonists: synthesis, biological evaluation, and development of an A1 bovine receptor model. 137
Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model 137
6-Substituted pyrazolo[3,4-d]pyrimidines: new promising compounds in the fight against Neuroblastoma 137
Pyrazolo[3,4-d]pyrimidines c-Src inhibitors reduce epidermal growth factor-induced migration in prostate cancer cells. 137
Totale 16.064
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Categoria #
all - tutte 122.934
article - articoli 92.136
book - libri 0
conference - conferenze 27.124
curatela - curatele 0
other - altro 0
patent - brevetti 2.554
selected - selezionate 0
volume - volumi 1.120
Totale 245.868
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20223.178 59 196 291 409 95 221 233 766 158 222 135 393
2022/20232.864 290 171 31 321 450 512 0 206 527 25 286 45
2023/20241.626 70 265 47 186 121 193 98 62 103 52 133 296
2024/20254.951 87 384 173 327 777 581 432 679 181 288 415 627
2025/202610.199 983 254 933 770 1.265 1.022 1.594 579 705 1.060 515 519
2026/2027955 955 0 0 0 0 0 0 0 0 0 0 0
Totale 38.683