DE TULLIO, ROBERTA
 Distribuzione geografica
Continente #
EU - Europa 9.043
AS - Asia 68
SA - Sud America 19
AF - Africa 2
NA - Nord America 2
Totale 9.134
Nazione #
IT - Italia 9.042
CN - Cina 48
VN - Vietnam 16
BR - Brasile 15
AR - Argentina 3
ID - Indonesia 2
MA - Marocco 2
US - Stati Uniti d'America 2
BD - Bangladesh 1
BY - Bielorussia 1
SG - Singapore 1
VE - Venezuela 1
Totale 9.134
Città #
Genova 5.512
Genoa 2.273
Vado Ligure 664
Rapallo 588
Beijing 22
Bordighera 5
Ho Chi Minh City 5
Ashburn 2
Haiphong 2
Agadir 1
Brasília 1
Buôn Dơn 1
Bình Dương 1
Campina Grande 1
Campinas 1
Campo Grande 1
Catamarca 1
Gualeguaychú 1
Hanoi 1
Hortolândia 1
Igrejinha 1
Lagoa Santa 1
Long An 1
Luiz Alves 1
Lấp Vò 1
Maracaibo 1
Minsk 1
Osasco 1
Palmas 1
Porto Alegre 1
Rio de Janeiro 1
Salé 1
Sete Lagoas 1
Singapore 1
São Paulo 1
Thái Bình 1
Tây Ninh 1
Urdinarrain 1
Viamão 1
Totale 9.103
Nome #
"Intracellular calpastatin proteolysis: a salvage mechanism or a prelude to cell damage?" 242
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 213
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 196
Activation of Ca2+-dependent proteolysis in skeletal muscle and heart in cancer cachexia. 183
Role of the calpain-calpastatin system in the density-dependent growth arrest 182
Evidence for alteration of calpain/calpastatin system in PBMC of cystic fibrosis patients 179
Calpain inhibition promotes the rescue of F(508)del-CFTR in PBMC from cystic fibrosis patients. 175
Calpain3 is expressed in a proteolitically active form in papillomavirus-associated urothelial tumors of the urinary bladder in cattle. 173
A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation 171
Involvement of exon 6-mediated calpastatin intracellular movements in the modulation of calpain activation. 167
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain. 166
Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex. 165
Characterization of a new p94-like calpain form in human lymphocytes 162
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 162
Cell protection from Ca2+-overloading by bioactive molecules extracted from olive pomace 158
Degradation of CFTR-generated protein clusters by calpain: A physiological or a pathological role? 153
Characterization of the calpastatin defect in erythrocytes from patients with essential hypertension. 152
Changes in calpastatin localization and expression during calpain activation: a new mechanism for the regulation of intracellular Ca(2+)-dependent proteolysis. 151
Multiple rat brain calpastatin forms are produced by distinct starting points and alternative splicing of the N-terminal exons. 147
The role of calpain in the selective increased phosphorylation of the anion-transport protein in red cell of hypertensive subjects. 146
Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90. 146
Regulation of calpain activity in rat brain with altered Ca2+ homeostasis 146
Role of the regulatory domain of calpastatin in the autoproteolytic activation of calpain 146
Identification of a novel neutrophil membrane protein involved in modulation of oxidative burst. 141
Involvement of erythrocyte calpain in glycine- and carnitine-treated isovaleric acidemia. 140
Interaction between Calpain-1 and HSP90: New Insights into the Regulation of Localization and Activity of the Protease. 139
Changes in intracellular localization of calpastatin during calpain activation 138
"Association of calpastatin with inactive calpain: a novel mechanism to control the activation of the protease?" 137
Changes in intracellular calpastatin localization are mediated by reversible phosphorylation 136
A Bioactive Olive Pomace Extract Prevents the Death of Murine Cortical Neurons Triggered by NMDAR Over-Activation 135
The calpastatin defect in hypertension is possibly due to a specific degradation by calpain. 134
“In vivo degradation of Nitric-Oxide Synthase isozymes by Calpain is regulated by HSP90” 133
Age-dependent degradation of calpastatin in kidney of hypertensive rats 132
Role of calpain in the regulation of CFTR (cystic fibrosis transmembrane conductance regulator) turnover 132
"Cytosolic levels of calpastatin are regulated by limited proteolysis" 126
“Susceptibility of NOS isoforms to calpain digestion is modulated by the expression levels of HSP90” 125
Role of calpain-1 in the early phase of experimental ALS 125
Different susceptibility of red cell membrane proteins to calpain degradation. 122
Interference with Ca2+-Dependent Proteolysis Does Not Alter the Course of Muscle Wasting in Experimental Cancer Cachexia. 121
Cytosolic levels of calpastatin are regulated by limited proteolysis 119
Is the Expression of [-G93A(+)] human SOD1 a model to study neurodegenerations? 118
Adaptive modifications in the calpain/calpastatin system in brain cells after persistent alteration in Ca2+ homeostasis 117
Bioactive molecules isolated from olive pomace extract protect cells from calcium mediated damages 116
In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS-HSP90 heterocomplex 115
Calpain-mediated activation of NO synthase in human neuroblastoma SK-N-BE cells 114
Phosphorylation of rat brain calpastatins by protein kinase C. 114
Properties of calpastatin forms in rat brain 109
Modulation of rat brain calpastatin efficiency by post-translational modifications 105
Association of calpastatin with inactive calpain: a novel mechanism to control the activation of the protease? 104
Differential degradation of calpastatin by mu- and m-calpain in Ca(2+)-enriched human neuroblastoma LAN-5 cells. 104
“Involvement of the Calpain/Calpastatin System in Familial Amyotrophic Lateral Sclerosis” 103
“How is alteration in Ca2+ homeostasis controlled in brain? A role for calpastatin” 98
Enhanced activation of the respiratory burst oxidase in neutrophils from hypertensive patients. 98
Regulation of the calpain-calpastatin system in rat brain during alteration of Ca2+ homeostasis 96
Site-directed activation of calpain is promoted by a membrane-associated natural activator protein 96
The calpain-calpastatin system in human central nervous system tumours: new insight on its prognostic value 92
“Regulation of calpain activity in brain following altered Ca2+ homeostasis” 91
Rat brain contains multiple mRNAs for calpastatin 91
Production and purification of recombinant calpastatin 91
Isolation of endogenous calpastatin 90
Specific role of calpain-1 associated to N-methy l-D-aspartate receptor in lipid rafts microdomains 87
Temperature-Dependent Olive Pomace Extraction for Obtaining Bioactive Compounds Preventing the Death of Murine Cortical Neurons 82
Interaction between catalitically inactive calpain and calpastatin: evidence for its occurrence in stimulated cells 81
Modulation of calpastatin specificity in rat tissues by reversible phosphorylation and dephosphorylation. 79
Expression of calpastatin hcast 3-25 and activity of the calpain/calpastatin system in human glioblastoma stem cells: possible involvement of hcast 3-25 in cell differentiation 78
Differential regulation of mu- and m-calpain in rat hearts perfused with Ca2+ and cAMP. 77
“Entry in the quiescent G0 cell state requires enhanced calpain activation” 76
Specific degradation of troponin T and I by mu-calpain and its modulation by substrate phosphorylation. 74
Immunoblotting for calpastatin expression 74
Respiratory burst in activated neutrophis is directly correlated to the intracellular level of protein kinase C 73
Functional role of HSP90 complexes with endothelial nitric-oxide synthase (eNOS) and calpain on nitric oxide generation in endothelial cells 71
Identification of potential leukocyte biomarkers related to drug recovery of cftr: Clinical applications in cystic fibrosis 66
Modulation of Plasmatic Matrix Metalloprotease 9: A Promising New Tool for Understanding the Variable Clinical Responses of Patients with Cystic Fibrosis to Cystic Fibrosis Transmembrane Conductance Regulator Modulators 47
GenBank: MF577037.1: Homo sapiens clone hcast 3-25 calpastatin (CAST) mRNA, partial cds 33
GenBank: MK585065.1: Homo sapiens calpastatin (CAST) mRNA, complete cds 32
Possible etiological association of ovine papillomaviruses with bladder tumors in cattle 25
Pro-inflammatory role of extracellular nicotinamide phosphoribosyltransferase in cystic fibrosis 8
Pro-inflammatory role of extracellular nicotinamide phosphorybosiltransferase in cystic fibrosis 8
Pro-inflammatory role of extracellular nicotinamide phosphorybosiltransferase in cystic fibrosis 8
Totale 9.257
Categoria #
all - tutte 28.941
article - articoli 21.383
book - libri 0
conference - conferenze 6.257
curatela - curatele 0
other - altro 444
patent - brevetti 0
selected - selezionate 0
volume - volumi 857
Totale 57.882


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021330 0 0 0 0 25 36 26 52 36 68 36 51
2021/2022899 31 72 56 84 24 56 63 212 36 88 37 140
2022/2023711 60 41 8 90 98 116 1 52 126 6 100 13
2023/2024487 23 53 8 48 54 116 20 16 29 13 29 78
2024/20251.707 131 130 37 108 199 179 174 254 96 56 163 180
2025/2026730 293 59 159 196 23 0 0 0 0 0 0 0
Totale 9.257