IRIS
BRAMBILLA, GIOVANNI
 Distribuzione geografica
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Continente #
EU - Europa 12.279
AS - Asia 6
SA - Sud America 3
NA - Nord America 1
Totale 12.289
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Nazione #
IT - Italia 12.278
CN - Cina 3
VN - Vietnam 3
BR - Brasile 2
CO - Colombia 1
EE - Estonia 1
US - Stati Uniti d'America 1
Totale 12.289
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Città #
Genova 8.209
Genoa 2.338
Rapallo 1.041
Vado Ligure 673
Bordighera 17
Ho Chi Minh City 3
Ashburn 1
Maicao 1
Rio de Janeiro 1
Tallinn 1
Torres 1
Yuncheng 1
Totale 12.287
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Nome #
Keynote comment: nitrosatable drugs, cancer, and guidelines for genotoxicity 182
FORMATION OF DNA-DAMAGING NITROSO COMPOUNDS BY INTERACTION OF DRUGS WITH NITRITE. A PRELIMINARY SCREENING FOR DETECTING POTENTIALLY HAZARDOUS DRUGS. 180
DNA DAMAGE INDUCED IN RATS BY ORAL ADMINISTRATION OF CHLORDIAZEPOXIDE PLUS SODIUM NITRITE OR OF N-NITROSOCHLORDIAZEPOXIDE 175
DNA DAMAGE IN LIVER, COLON, STOMACH, LUNG AND KIDNEY OF BALB/C MICE TREATED WITH 1,2-DIMETHYLHYDRAZINE. 172
Comparison of micronuclei frequencies in mono-, bi- and poly-nucleated lymphocytes from subjects of a residential suburb and subjects living near a metallurgical plant 168
Are some progestins genotoxic liver carcinogens? 166
Increased frequency of micronucleated kidney cells in rats exposed to halogenated anaesthetics. 163
AN IN VIVO MICRONUCLEUS ASSAY FOR DETECTING THE CLASTOGENIC EFFECT IN RAT KIDNEY CELLS. 162
A STUDY OF THE POTENTIAL GENOTOXICITY OF CIMETIDINE USING HUMAN HEPATOCYTE PRIMARY CULTURES: DISCREPANCY FROM RESULTS OBTAINED IN RAT HEPATOCYTES. 157
Comparative study of DNA repair induced by cyproterone acetate, chlormadinone acetate and megestrol acetate in primary cultures of human and rat hepatocytes. 157
GENOTOXIC EFFECTS IN RODENTS GIVEN HIGH ORAL DOSES OF RANITIDINE AND SODIUM NITRITE. 154
Formation of DNA-damaging N-nitroso compounds from the interaction of calcium-channel blockers with nitrite 154
DNA-damaging activity of biotic and xenobiotic aldehydes in Chinese hamster ovary cells. 153
Comparison in human and rat hepatocytes of the DNA-damaging activity of five chemicals probably carcinogenic to humans. 151
Genotoxicity and carcinogenicity studies of antihypertensive agents 150
Studies on genotoxicity and carcinogenicity of antibacterial, antiviral, antimalarial and antifungal drugs. 147
Testing of metoclopramide and procainamide for their ability to induce genotoxic effects in cultured mammalian cells. 146
DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by chemicals carcinogenic to the rat thyroid 145
Pharmaceutical companies provide insufficient information about genotoxicity and carcinogenicity assays 141
Discrepancies between use of antihypertensive drugs and guidelines indications: pharmacoeconomic implications 140
GENOTOXICITY OF CIMETIDINE IN PRIMARY CULTURES OF RAT HEPATOCYTES. 139
Higher sensitivity for the detection of chemically-induced DNA damage: role of DNA unfolding in determining alkaline elution rate 139
ALKALINE ELUTION ASSAY AS A POTENTIALLY USEFUL METHOD FOR ASSESSING DNA DAMAGE INDUCED "IN VIVO" BY DIAZOALKANES. 138
Use of human thyroid cell primary cultures for genotoxicity studies 138
DNA alkaline elution: physical basis of the elution process and validation of this method as a screening procedure to identify chemical carcinogens. 137
Arylamine drugs: genotoxic-carcinogenic activity of NO-derivatives 137
REDUCTION OF DNA REPAIR EFFICIENCY DURING THE INITIAL PHASE OF RAT LIVER CARCINOGENESIS. 136
DNA repair synthesis and DNA fragmentation in primary cultures of human and rat hepatocytes exposed to cyproterone acetate. 136
Comparison of micronucleus formation in mouse bone marrow and spleen. 134
Methylglyoxal-induced DNA-protein cross-links and cytotoxicity in Chinese hamster ovary cells 133
DNA DAMAGE INDUCED BY SEVEN N-NITROSOCOMPOUNDS IN PRIMARY CULTURES OF HUMAN AND RAT KIDNEY CELLS. 132
Genotoxicity testing of chloramphenicol in rodent and human cells 131
Ipriflavone inhibits osteoclast differentiation in parathyroid transplanted parietal bone of rats 130
The effect of benzenediols and benzenetriols on the nitrosation of propranolol depends on the position of hydroxyl groups on the benzene ring 130
Cynnamaldehyde-induced micronuclei in rodent liver 130
DNA-DAMAGING AND MUTAGENIC PROPERTIES OF 2-NITROPROPANE IN RODENTS AND HUMAN CELLS. 129
Human hepatocyte primary cultures in toxicity assessment 129
Update of carcinogenicity studies in animals and humans of 535 marketed pharmaceuticals 129
Comparison of the sensitivity of human and rat hepatocytes to genotoxic effects of metronidazole 129
Correlation between induction of DNA fragmentation in urinary bladder cells from rats and humans and tissue-specific carcinogenic activity. 128
Physico-chemical model for DNA alkaline elution: new experimental evidence and differential role of DNA length, chain flexibility and superpacking 127
Grain counting in the in vitro hepatocyte DNA-repair assay. 127
COMPARATIVE EFFECTS OF CHEENODEOXYCHOLIC (CDCA) AND URSODEOXYCHOLIC ACID (UDCA) IN PREGNAT RATS. 126
Genotoxicity and carcinogenicity studies of antihistamines. 125
Species, sex and inter-individual differences in DNA repair induced by nine sex steroids in primary cultures of rat and human hepatocytes 125
DNA FRAGMENTATION BY N-NITROSODIMETHYLAMINE AND METHYL METHANESULFONATE IN HUMAN HEPATOCYTE PRIMARY CULTURES. 124
Update on genotoxicity and carcinogenicity testing of 472 marketed pharmaceuticals 124
Induction of sister-chromatid exchanges in Chinese hamster ovary cells of biotic ketoaldehyde methylglyoxal. 123
DNA DAMAGE AND REPAIR INDUCED IN RAT HEPATOCYTE PRIMARY CULTURES BY FIVE ANTIHISTAMINES AND THEIR NITROSATION PRODUCTS. 123
Genotoxicity of N-nitrosochlordiazepoxide in cultured mammalian cells. 123
DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by four rat thyroid carcinogens 123
Effects of mono-, di- and tri-hydroxybenzoic acids on the nitrosation of propranolol: structure-activity relationship 122
INDUCTION OF DNA FRAGMENTATION AND DNA REPAIR SYNTHESIS IN HUMAN AND RAT HEPATOCYTES BY DIETHYLSTILBESTROL. 122
Cytotoxic and Genotoxic activity of 1,3-dichloropropene in cultured mammalian cells. 122
DNA damage induced by 3,3’-dimethoxybenzidine in liver and urinary bladder cells of rats and humans 122
Genotoxicity and carcinogenicity studies of benzodiazepines 121
Correlation between induction of DNA fragmentation in lung cell from rats and humans and carcinogenicity activity 121
Mutagenicity in V79 Chinese hamster cells of n-alkanals produced by lipid peroxidation 120
Nitrosation of propranolol under simulated gastric conditions. 119
DNA damage induced by nitrosated ranitidine in cultured mammalian cells. 119
Genotoxicity testing of potassium canrenoate in cultured rat and human cells 117
Correlation between induction of DNA fragmentation and micronuclei formation in kidney cells from rats and human and tissue-specific carcinogenic activity. 116
Lack of evidence of omeprazole genotoxicity in Sprague-Dawley rats. 116
Is lipid peroxidation associated with DNA damage? 116
DNA DAMAGE AND REPAIR IN MOUSE TISSUES FOLLOWING PROCARBAZINE ADMINISTRATION. 115
Genotoxicity and carcinogenicity studies of bronchodilators and antiasthma drugs 113
Genotoxic and carcinogenic effects of gastrointestinal drugs 112
Genotoxic and carcinogenic risk to humans of drug-nitrite interaction products. 111
Human hepatocytes in genotoxicity assays 111
Guidelines for the clinical use of albumin; comparison of use in two Italian hospitals and a third hospital without guidelines. 111
GENOTOXIC ACTIVITY OF 1,3-DICHLOROPROPENE IN A BATTERY OF IN VIVO SHORT-TERM TESTS. 111
Viscoelastic properties of native DNA from intact nuclei of mammalian cells. Higher-order DNA packing and cell function 110
COMPARATIVE STUDY OF DNA DAMAGE AND REPAIR INDUCED BY TEN N-NITROSO COMPOUNDS IN PRIMARY CULTURES OF HUMAN AND RAT HEPATOCYTES. 109
Evaluation of omeprazole genotoxicity in a battery of in vitro and in vivo assays 108
The questionable use of antihypertensive drugs in the Italian Liguria Region in the year 2003 108
DNA-DAMAGING ACTIVITY OF TRIPELENNAMINE IN PRIMARY CULTURES OF HUMAN HEPATOCYES. 106
Evaluation of DNA-damaging, clastogenic and promoting activities of metoclopramide and procainamide in rats. 105
Failure of the standard battery of short-term tests in detecting some rodent and human genotoxic carcinogens 105
Genotoxicity and carcinogenicity studies of analgesics, anti-inflammatory drugs and antipyretics. 104
Induction of micronuclei and of enzyme-altered foci in the liver of female rats exposed to progesterone and three synthetic progestins. 103
Evaluation in a battery of in vivo assays of four in vitro genotoxins proved to be noncarcinogens in rodents. 102
QUANTITATIVE CORRELATION AMONG DNA DAMAGING POTENCY OF N-NITROSO COMPOUNDS AND THEIR POTENCY IN INDUCING TUMOR GROWTH AND BACTERIAL MUTATIONS. 101
DNA damage and micronuclei induced in rat and human kidney cells by six chemicals carcinogenic to the rat kidney 101
DNA fragmentation, DNA repair and apoptosis induced in primary rat hepatocytes by dienogest, dydrogesterone and 1,4,6-androstatriene-17beta-ol-3-one acetate 101
CYTOTOXIC, DNA-DAMAGING AND MUTAGENIC PROPERTIES OF 2,6-DIMETHOXY-1,4-BENZOQUINONE, FORMED BY DIMETHOPHRINE-NITRITE INTERACTION. 100
DNA-DAMAGING ACTIVITY "IN VIVO" AND BACTERIAL MUTAGENICITY OF SIXTEEN HYDRAZINE DERIVATIVES AS RELATED QUANTITATIVELY TO THEIR CARCINOGENICITY. 99
COMPARISON OF DNA ALKYLATION, FRAGMENTATION, AND REPAIR IN MATERNAL AND FETAL TISSUES OF PREGNANT RATS TREATED WITH A SINGLE DOSE OF ETHYL METHANESULFONATE, ETHYL-N-NITROSOUREA, N-NITROSODIMETHYLAMINE, AND METHYL-N-NITROSOUREA. 97
DNA damage induced by 4,4'-methylenedianiline in primary cultures of hepatocytes and thyreocytes from rats and humens 93
DNA fragmentation by 2-nitropropane in rat tissues, and effects of the modulation of biotransformation processes. 91
Induction and promotion of gamma-glutamiltranspeptidase-positive foci in the rat liver by methylglyoxal 90
Sequential analysis of DNA damage and repair during the development of carcinogen-induced rat liver hyperplastic lesions 89
Genotoxicity and carcinogenicity testing of pharmaceuticals: Correlations between induction of DNA lesions and carcinogenic activity 85
GENOTOXIC ACTIVITY OF FIVE ANTIDEPRESSANT HYDRAZINES IN A BACTERY OF "IN VIVO" AND "IN VITRO" SHORT-TERM TESTS. 83
Genotoxic and carcinogenic effects of antipsycotics and antidepressants 82
Formation of the N-nitroso derivatives of six beta-adrenergic blocking agents and their genotoxic effects in rat and human hepatocytes. 81
Low clastogenic activity in vivo of the N-nitrosoderivatives of five (-adrenergic-blocking drugs proved to be potent genotoxins in vitro 78
Induction of micronuclei and inhibition of enzyme-altered foci in the liver of female rats treated with cyproterone acetate, chlormadinone acetate or megestrol acetate 75
DNA damage in tissues of rat treated with potassium canrenoate 69
Genotoxic effects of alfa-hexachlorocyclohexane in primary cultures of rodents and human hepatocytes 68
Comparison of the Sensitivity of Human and Rat Hepatocytes to the Genotoxic Effects of Metronidazole 63
Totale 12.240
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Categoria #
all - tutte 37.306
article - articoli 36.528
book - libri 401
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 377
Totale 74.612
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021436 0 0 0 0 29 63 20 68 61 65 56 74
2021/20221.232 21 138 105 110 53 69 62 316 32 103 70 153
2022/20231.237 116 91 25 145 203 232 0 100 230 4 70 21
2023/2024620 36 81 9 87 37 202 22 42 24 10 19 51
2024/20251.597 20 135 42 87 219 202 124 288 33 69 175 203
2025/2026630 374 48 93 115 0 0 0 0 0 0 0 0
Totale 12.327