IRIS
BOTTINO, CRISTINA
 Distribuzione geografica
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Continente #
EU - Europa 24.152
AS - Asia 2.262
NA - Nord America 854
SA - Sud America 175
AF - Africa 41
OC - Oceania 4
Totale 27.488
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Nazione #
IT - Italia 23.759
SG - Singapore 990
US - Stati Uniti d'America 802
CN - Cina 610
VN - Vietnam 410
FR - Francia 188
BR - Brasile 102
HK - Hong Kong 78
DE - Germania 47
FI - Finlandia 46
JP - Giappone 31
AR - Argentina 28
MX - Messico 27
GB - Regno Unito 23
BD - Bangladesh 21
IN - India 20
CH - Svizzera 19
CA - Canada 18
IQ - Iraq 17
PH - Filippine 16
ID - Indonesia 15
NL - Olanda 14
EC - Ecuador 12
PY - Paraguay 8
VE - Venezuela 8
ZA - Sudafrica 8
RU - Federazione Russa 7
UZ - Uzbekistan 7
ES - Italia 6
PK - Pakistan 6
SA - Arabia Saudita 6
TH - Thailandia 6
TR - Turchia 6
CL - Cile 5
CO - Colombia 5
DZ - Algeria 5
EG - Egitto 5
IE - Irlanda 5
MA - Marocco 5
RO - Romania 5
AT - Austria 4
AU - Australia 4
PE - Perù 4
UA - Ucraina 4
AL - Albania 3
CR - Costa Rica 3
OM - Oman 3
PL - Polonia 3
SI - Slovenia 3
AE - Emirati Arabi Uniti 2
AO - Angola 2
BG - Bulgaria 2
BO - Bolivia 2
CZ - Repubblica Ceca 2
DJ - Gibuti 2
ET - Etiopia 2
GR - Grecia 2
GT - Guatemala 2
JO - Giordania 2
KE - Kenya 2
LT - Lituania 2
MY - Malesia 2
PS - Palestinian Territory 2
PT - Portogallo 2
SE - Svezia 2
TN - Tunisia 2
TW - Taiwan 2
AZ - Azerbaigian 1
BF - Burkina Faso 1
BW - Botswana 1
CG - Congo 1
DK - Danimarca 1
GA - Gabon 1
HN - Honduras 1
KG - Kirghizistan 1
KR - Corea 1
KZ - Kazakistan 1
LB - Libano 1
LK - Sri Lanka 1
MK - Macedonia 1
MO - Macao, regione amministrativa speciale della Cina 1
MT - Malta 1
MU - Mauritius 1
NG - Nigeria 1
NI - Nicaragua 1
NP - Nepal 1
QA - Qatar 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SY - Repubblica araba siriana 1
UY - Uruguay 1
YT - Mayotte 1
Totale 27.488
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Città #
Genova 15.351
Genoa 4.932
Rapallo 1.851
Vado Ligure 1.513
Singapore 411
San Jose 407
Lauterbourg 177
Ho Chi Minh City 129
Beijing 93
Hanoi 92
Ashburn 82
Hong Kong 73
Council Bluffs 56
Bordighera 51
New York 51
Helsinki 44
Frankfurt am Main 42
Santa Clara 27
Tokyo 26
Haiphong 22
Zurich 19
Da Nang 17
Mexico City 17
Tianjin 13
Amsterdam 12
Los Angeles 12
Montreal 11
Shanghai 11
Milan 10
Orem 10
Baghdad 8
Biên Hòa 8
City of London 8
São Paulo 8
Chicago 7
Tashkent 7
Bangkok 6
Jakarta 6
Ninh Bình 6
Can Tho 5
Dallas 5
Dublin 5
Johannesburg 5
Paris 5
Rome 5
Toronto 5
Brasília 4
Buenos Aires 4
Bắc Giang 4
Caracas 4
Des Moines 4
Lima 4
London 4
Mumbai 4
Shenyang 4
Sydney 4
Asunción 3
Atlanta 3
Buffalo 3
Cairo 3
Cao Lanh 3
Cardiff 3
Chennai 3
Dhaka 3
Guangzhou 3
Hưng Yên 3
Hải Dương 3
Kyiv 3
Lahore 3
Madrid 3
Manchester 3
Miguel Hidalgo 3
Nuremberg 3
Quảng Ngãi 3
Quận Ba 3
Riyadh 3
San José 3
Santa Rosa 3
Thái Bình 3
Thái Nguyên 3
Wuhan 3
Addis Ababa 2
Amman 2
Athens 2
Basra 2
Benito Juarez 2
Berazategui 2
Bogotá 2
Bra 2
Brugnera 2
Bắc Ninh 2
Cachoeiras de Macacu 2
Changsha 2
Curitiba 2
Denver 2
Duhok 2
Duque de Caxias 2
Florence 2
Formosa 2
Fortaleza 2
Totale 25.814
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Nome #
Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function 250
PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance 245
PVR(CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis 232
NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27 220
Main NK cell receptors and their ligands: regulation by microRNAs 219
Natural Killer Cells and Neuroblastoma: Tumor Recognition, Escape Mechanisms, and Possible Novel Immunotherapeutic Approaches. 212
GPR56 as a novel marker identifying the CD56dull CD16+ NK cell subset both in blood stream and in inflamed peripheral tissues. 211
Both CD133(+) and CD133(-) medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK-mediated cytotoxicity 209
2B4 functions as a co-receptor in human NK cell activation 208
M-CSF induces the expression of a membrane-bound form of IL-18 in a subset of human monocytes differentiating in vitro toward macrophages 200
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation. 196
A novel surface molecule expressed by long-term cultured T and natural killer cells is involved in cell activation. 194
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells. 190
X-linked lymphoproliferative disease: the dark side of 2B4 function. 187
Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells 184
Function and specificity of human natural killer cell receptors. 184
A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s). 181
Nidogen-1 is a novel extracellular ligand for the NKp44 activating receptor 181
Analysis of natural killer cells in TAP2-deficient patients: expression of functional triggering receptors and evidence for the existence of inhibitory receptor(s) that prevent lysis of normal autologous cells 179
Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function. 178
Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses 177
The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes. 175
NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy? 172
Molecular mechanisms directing migration and retention of natural killer cells in human tissues 172
Identification of NKp80, a novel triggering molecule expressed by human NK cells. 170
Antigen recognition by human T cell receptor gamma-positive lymphocytes. Specific lysis of allogeneic cells after activation in mixed lymphocyte culture. 170
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells 170
Learning how to discriminate between friends and enemies,a lesson from Natural Killer cells 169
Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors. 169
Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis. 168
Human NK cells and NK receptors 168
Human NK receptors: from the molecules to the therapy of high risk leukemias. 168
Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules. 168
KIR and KIR ligand polymorphism: a new area for clinical applications? 167
Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors 166
Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction 165
CIS is a negative regulator of IL-15-mediated signals in NK cells 165
In vivo generation of decidual Natural Killer cells from resident hematopoietic progenitors. 164
Cell-laden hydrogel as a clinical-relevant 3D model for analyzing neuroblastoma growth, immunophenotype, and susceptibility to therapies 164
CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity 161
Triggering receptors involved in natural killer cell-mediated cytotoxicity against choriocarcinoma cell lines 161
Surface receptors that regulate the NK cell function: beyond the NK cell scope. 160
Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis 160
A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency 160
Cellular ligands for activating NK receptors 159
CD4(+) cutaneous T-cell lymphoma cells express the p140-killer cell immunoglobulin-like receptor. 159
Small round blue cell tumours: diagnostic and prognostic usefulness of the expression of B7-H3 surface molecule. 159
Description of the novelKIR2DL4*035allele identified using high-throughput sequencing 159
X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells. 158
Cell surface expression of activating receptors and co-receptors on peripheral blood NK cells in systemic autoimmune diseases. 156
Imatinib and nilotinib off-target effects on human NK cells, monocytes, and M2 macrophages 156
Oxysterol mixture and, in particular, 27-hydroxycholesterol drive M2 polarization of human macrophages 155
Overview of the Soluble and Membrane-bound Tumor Factors Limiting NKmediated Immune Surveillance 155
DNAM-1 and PVR regulate monocyte migration through endothelial junctions 154
Natural killer lymphocytes: "null cells" no more. 154
Human T lymphocytes expressing TCR gamma/delta. 154
Novel Immunoregulatory Functions of IL-18, an Accomplice of TGF-β1 153
Immunobiology of human NK cells. 152
A novel 120-kD surface antigen expressed by a subset of human lymphocytes. Evidence that lymphokine-activated killer cells express this molecule and use it in their effector function. 152
Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery. 152
Surface receptors and functional interactions of human natural killer cells: from bench to the clinic 152
Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients 152
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells 152
Expression of the DNAM-1 ligands Nectin-2 (CD112) and poliovirus receptor (CD155) on dendritic cells: relevance for natural killer/dendritic cells interaction 152
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells 150
NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells 149
Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition. 149
A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. 149
Natural killer cell-mediated recognition of human trophoblast. 148
Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation. 148
Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells. 148
Subpopulations of human NK (CD3-CD16+) lymphocytes identified by monoclonal antibodies directed to clonally distributed functional surface molecules. 147
Neuroblastoma-derived transforming growth factor (TGF) β1 modulates the chemokine receptor repertoire of human resting Natural Killer Cells. 147
TLR activation of tumor-associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells. 147
Human natural killer cells: their origin, receptors and function 145
Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. 144
2B4 dysfunction in XLP1 NK cells: More than inability to control EBV infection 143
Human natural killer cell function and receptors. 142
Human peripheral blood lymphocytes bearing T cell receptor gamma/delta. Expression of CD8 differentiation antigen correlates with the expression of the 55-kD, C gamma 2-encoded gamma chain. 142
The human natural cytotoxicity receptors (NCR) that induce HLA class I-independent NK cell triggering 141
Soluble HLA-G dampens CD94/NKG2A expression and function and differentially modulates chemotaxis and cytokine and chemokine secretion in CD56bright and CD56dim NK cells. 141
TGF-beta1 downregulates the expression of CX3CR1 by inducing miR-27a-5p in primary human NK cells 141
The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity. 140
PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance 140
Cellular and molecular basis of natural killer and natural killer-like activity. 140
Neuroblastoma-Derived TGF-beta1 Modulates the Chemokine Receptor Repertoire of Human Resting NK Cells. 139
CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies. 139
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells 139
Different checkpoints in human NK-cell activation 138
Identification of a new surface molecule involved in the mechanism of cell to cell adhesion between human NK and tumor target cells. 137
Identification of the rat homologue of the human NKp46 triggering receptor 137
Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. 136
Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin 135
Surface receptors delivering opposite signals regulate the function of human NK cells 135
Human natural killer cell activating receptors. 135
Human thymocytes expressing gamma/delta T-cell receptors. 135
HLA-specific and non-HLA-specific human NK receptors. 134
Cell surface expression of activating receptors and co-receptors on peripheral blood NK cells in mixed cryoglobulinemia. 134
Human natural killer cells: molecular mechanisms controlling NK cell activation and tumor cell lysis 133
Functional characterization of natural killer cells in type I leukocyte adhesion deficiency 132
Totale 16.243
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Categoria #
all - tutte 81.360
article - articoli 77.092
book - libri 0
conference - conferenze 1.886
curatela - curatele 0
other - altro 0
patent - brevetti 2.050
selected - selezionate 0
volume - volumi 332
Totale 162.720
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021384 0 0 0 0 0 0 0 0 0 178 92 114
2021/20222.283 84 190 196 300 67 126 157 494 86 222 90 271
2022/20232.263 251 154 18 247 375 400 4 150 434 15 179 36
2023/20241.097 51 184 35 150 79 134 33 78 91 39 93 130
2024/20253.491 65 266 161 204 556 321 359 499 132 162 353 413
2025/20265.310 674 150 311 505 790 592 999 317 461 511 0 0
Totale 27.805