IRIS
BOTTINO, CRISTINA
 Distribuzione geografica
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Continente #
EU - Europa 23.679
AS - Asia 110
SA - Sud America 54
NA - Nord America 3
AF - Africa 2
Totale 23.848
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Nazione #
IT - Italia 23.676
CN - Cina 71
BR - Brasile 45
VN - Vietnam 19
SG - Singapore 12
ID - Indonesia 7
AR - Argentina 5
EC - Ecuador 3
MX - Messico 2
BG - Bulgaria 1
KZ - Kazakistan 1
PY - Paraguay 1
RU - Federazione Russa 1
TN - Tunisia 1
UA - Ucraina 1
US - Stati Uniti d'America 1
ZA - Sudafrica 1
Totale 23.848
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Città #
Genova 15.351
Genoa 4.908
Rapallo 1.851
Vado Ligure 1.513
Bordighera 51
Beijing 40
Ho Chi Minh City 8
Hanoi 4
Curitiba 2
Jakarta 2
Milan 2
Singapore 2
São Paulo 2
Acaraú 1
Ambato 1
Ashburn 1
Asunción 1
Avaré 1
Barra Bonita 1
Ben Arous 1
Benito Juarez 1
Boa Vista 1
Bragança Paulista 1
Brasília 1
Buenos Aires 1
Cachoeiras de Macacu 1
Candelaria 1
Capivari 1
Cesário Lange 1
Da Nang 1
Duque de Caxias 1
Esteio 1
Farroupilha 1
Fortaleza 1
Guarulhos 1
Guayaquil 1
Hải Dương 1
Itamaraju 1
Itapevi 1
Itumbiara 1
Lages 1
Lajeado 1
Lauro de Freitas 1
Manaus 1
Mar del Plata 1
Marília 1
Medan 1
Miguel Hidalgo 1
Montes Claros 1
Moscow 1
Ninh Bình 1
Nova Lima 1
Palmas de Monte Alto 1
Pavlodar 1
Phủ Lý 1
Port Elizabeth 1
Presidente Prudente 1
Ribeirão 1
Ribeirão Preto 1
Ribeirão das Neves 1
Rio Branco 1
Santana de Parnaíba 1
Sleman 1
Sofia 1
Surabaya 1
Suzano 1
São Gonçalo 1
São José 1
São Mateus 1
São Mateus do Sul 1
Taquarussu 1
Teixeiras 1
Thái Nguyên 1
Tupã 1
Várzea Grande 1
Vũng Tàu 1
Xinguara 1
Zárate 1
Totale 23.801
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Nome #
Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function 225
PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance 210
PVR(CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis 206
Natural Killer Cells and Neuroblastoma: Tumor Recognition, Escape Mechanisms, and Possible Novel Immunotherapeutic Approaches. 192
NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27 192
Both CD133(+) and CD133(-) medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK-mediated cytotoxicity 188
2B4 functions as a co-receptor in human NK cell activation 186
Main NK cell receptors and their ligands: regulation by microRNAs 186
GPR56 as a novel marker identifying the CD56dull CD16+ NK cell subset both in blood stream and in inflamed peripheral tissues. 180
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation. 175
X-linked lymphoproliferative disease: the dark side of 2B4 function. 173
A novel surface molecule expressed by long-term cultured T and natural killer cells is involved in cell activation. 172
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells. 169
Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells 163
M-CSF induces the expression of a membrane-bound form of IL-18 in a subset of human monocytes differentiating in vitro toward macrophages 161
Analysis of natural killer cells in TAP2-deficient patients: expression of functional triggering receptors and evidence for the existence of inhibitory receptor(s) that prevent lysis of normal autologous cells 160
A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s). 159
Function and specificity of human natural killer cell receptors. 159
Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function. 158
The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes. 157
Identification of NKp80, a novel triggering molecule expressed by human NK cells. 156
Learning how to discriminate between friends and enemies,a lesson from Natural Killer cells 155
Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis. 154
Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses 153
Nidogen-1 is a novel extracellular ligand for the NKp44 activating receptor 153
Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules. 153
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells 151
Human NK receptors: from the molecules to the therapy of high risk leukemias. 151
KIR and KIR ligand polymorphism: a new area for clinical applications? 150
Molecular mechanisms directing migration and retention of natural killer cells in human tissues 150
Human NK cells and NK receptors 149
Triggering receptors involved in natural killer cell-mediated cytotoxicity against choriocarcinoma cell lines 148
Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors 147
CIS is a negative regulator of IL-15-mediated signals in NK cells 146
Surface receptors that regulate the NK cell function: beyond the NK cell scope. 145
Antigen recognition by human T cell receptor gamma-positive lymphocytes. Specific lysis of allogeneic cells after activation in mixed lymphocyte culture. 145
Cell surface expression of activating receptors and co-receptors on peripheral blood NK cells in systemic autoimmune diseases. 145
Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors. 143
Immunobiology of human NK cells. 142
CD4(+) cutaneous T-cell lymphoma cells express the p140-killer cell immunoglobulin-like receptor. 142
Description of the novelKIR2DL4*035allele identified using high-throughput sequencing 142
X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells. 141
In vivo generation of decidual Natural Killer cells from resident hematopoietic progenitors. 141
NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells 140
CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity 140
Cellular ligands for activating NK receptors 139
Surface receptors and functional interactions of human natural killer cells: from bench to the clinic 139
DNAM-1 and PVR regulate monocyte migration through endothelial junctions 139
Small round blue cell tumours: diagnostic and prognostic usefulness of the expression of B7-H3 surface molecule. 138
Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis 137
Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation. 136
NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy? 136
Natural killer lymphocytes: "null cells" no more. 136
Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction 135
Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery. 135
Human T lymphocytes expressing TCR gamma/delta. 135
Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients 134
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells 134
Cell-laden hydrogel as a clinical-relevant 3D model for analyzing neuroblastoma growth, immunophenotype, and susceptibility to therapies 134
Soluble HLA-G dampens CD94/NKG2A expression and function and differentially modulates chemotaxis and cytokine and chemokine secretion in CD56bright and CD56dim NK cells. 133
Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. 132
A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency 132
A novel 120-kD surface antigen expressed by a subset of human lymphocytes. Evidence that lymphokine-activated killer cells express this molecule and use it in their effector function. 131
Natural killer cell-mediated recognition of human trophoblast. 130
Expression of the DNAM-1 ligands Nectin-2 (CD112) and poliovirus receptor (CD155) on dendritic cells: relevance for natural killer/dendritic cells interaction 130
Human natural killer cells: their origin, receptors and function 129
The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity. 129
Subpopulations of human NK (CD3-CD16+) lymphocytes identified by monoclonal antibodies directed to clonally distributed functional surface molecules. 129
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells 129
Human peripheral blood lymphocytes bearing T cell receptor gamma/delta. Expression of CD8 differentiation antigen correlates with the expression of the 55-kD, C gamma 2-encoded gamma chain. 129
Different checkpoints in human NK-cell activation 129
2B4 dysfunction in XLP1 NK cells: More than inability to control EBV infection 129
Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells. 128
TLR activation of tumor-associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells. 127
Neuroblastoma-Derived TGF-beta1 Modulates the Chemokine Receptor Repertoire of Human Resting NK Cells. 126
CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies. 126
Cellular and molecular basis of natural killer and natural killer-like activity. 126
Imatinib and nilotinib off-target effects on human NK cells, monocytes, and M2 macrophages 126
The human natural cytotoxicity receptors (NCR) that induce HLA class I-independent NK cell triggering 125
Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles. 125
Overview of the Soluble and Membrane-bound Tumor Factors Limiting NKmediated Immune Surveillance 125
Identification of the rat homologue of the human NKp46 triggering receptor 125
Human natural killer cell function and receptors. 124
Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin 124
Identification of a new surface molecule involved in the mechanism of cell to cell adhesion between human NK and tumor target cells. 124
Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition. 124
Neuroblastoma-derived transforming growth factor (TGF) β1 modulates the chemokine receptor repertoire of human resting Natural Killer Cells. 124
Oxysterol mixture and, in particular, 27-hydroxycholesterol drive M2 polarization of human macrophages 124
Novel Immunoregulatory Functions of IL-18, an Accomplice of TGF-β1 124
A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. 122
PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance 121
Human thymocytes expressing gamma/delta T-cell receptors. 121
Surface receptors delivering opposite signals regulate the function of human NK cells 120
Cell surface expression of activating receptors and co-receptors on peripheral blood NK cells in mixed cryoglobulinemia. 119
CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta. 118
Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells. 118
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells 118
Human natural killer cell activating receptors. 117
Human natural killer cells: molecular mechanisms controlling NK cell activation and tumor cell lysis 116
HLA-specific and non-HLA-specific human NK receptors. 116
Totale 14.284
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Categoria #
all - tutte 75.003
article - articoli 71.131
book - libri 0
conference - conferenze 1.732
curatela - curatele 0
other - altro 0
patent - brevetti 1.880
selected - selezionate 0
volume - volumi 260
Totale 150.006
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021923 0 0 0 0 70 157 43 126 143 178 92 114
2021/20222.283 84 190 196 300 67 126 157 494 86 222 90 271
2022/20232.263 251 154 18 247 375 400 4 150 434 15 179 36
2023/20241.097 51 184 35 150 79 134 33 78 91 39 93 130
2024/20253.491 65 266 161 204 556 321 359 499 132 162 353 413
2025/20261.662 674 150 311 505 22 0 0 0 0 0 0 0
Totale 24.157