IRIS
TOMATI, VALERIA
 Distribuzione geografica
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Continente #
EU - Europa 1.097
AS - Asia 22
SA - Sud America 2
NA - Nord America 1
Totale 1.122
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Nazione #
IT - Italia 1.097
CN - Cina 19
BR - Brasile 2
SG - Singapore 2
SY - Repubblica araba siriana 1
US - Stati Uniti d'America 1
Totale 1.122
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Città #
Genoa 640
Genova 219
Rapallo 122
Vado Ligure 111
Beijing 11
Bordighera 4
Ashburn 1
José Bonifácio 1
Milan 1
Singapore 1
Torres 1
Totale 1.112
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Nome #
Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays 127
The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs 100
Targeting of Ubiquitin E3 Ligase RNF5 as a Novel Therapeutic Strategy in Neuroectodermal Tumors 99
High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel 97
Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel 96
Journey on VX-809-Based Hybrid Derivatives towards Drug-like F508del-CFTR Correctors: From Molecular Modeling to Chemical Synthesis and Biological Assays 89
Partial rescue of f508del-cftr stability and trafficking defects by double corrector treatment 82
The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism 77
Rescue by elexacaftor-tezacaftor-ivacaftor of the G1244E cystic fibrosis mutation's stability and gating defects are dependent on cell background 74
Patient's dermal fibroblasts as disease markers for visceral myopathy 65
Two CFTR mutations within codon 970 differently impact on the chloride channel functionality 63
Clinical Consequences and Functional Impact of the Rare S737F CFTR Variant and Its Responsiveness to CFTR Modulators 53
De novo variants in DENND5B cause a neurodevelopmental disorder 51
Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators 41
Evaluation of a systems biology approach to identify pharmacological correctors of the mutant {CFTR} chloride channel 24
CFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium 21
In silico, in vitro and ex vivo characterization of cystic fibrosis transmembrane conductance regulator pathogenic variants localized in the fourth intracellular loop and their rescue by modulators 10
Totale 1.169
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Categoria #
all - tutte 5.499
article - articoli 5.499
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 10.998
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021106 0 0 0 47 0 0 10 7 5 18 17 2
2021/2022120 0 4 1 9 3 5 2 18 10 21 32 15
2022/2023151 11 12 5 13 24 18 4 11 21 2 25 5
2023/2024102 5 11 4 17 8 18 3 7 5 4 8 12
2024/2025436 10 14 9 25 23 48 29 102 38 36 46 56
2025/2026230 107 19 52 52 0 0 0 0 0 0 0 0
Totale 1.169