IRIS
PEDEMONTE, NICOLETTA
 Distribuzione geografica
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Continente #
EU - Europa 1.348
AS - Asia 27
Totale 1.375
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Nazione #
IT - Italia 1.348
CN - Cina 21
SG - Singapore 5
SY - Repubblica araba siriana 1
Totale 1.375
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Città #
Genoa 967
Vado Ligure 180
Rapallo 123
Genova 73
Beijing 11
Bordighera 4
Milan 1
Singapore 1
Totale 1.360
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Nome #
Targeting of Ubiquitin E3 Ligase RNF5 as a Novel Therapeutic Strategy in Neuroectodermal Tumors 99
The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs 99
Journey on VX-809-Based Hybrid Derivatives towards Drug-like F508del-CFTR Correctors: From Molecular Modeling to Chemical Synthesis and Biological Assays 88
Neutrophil Extracellular Traps in Systemic Lupus Erythematosus Stimulate IgG2 Production From B Lymphocytes 83
Partial rescue of f508del-cftr stability and trafficking defects by double corrector treatment 82
Genotype-phenotype correlations and disease mechanisms in PEX13-related Zellweger spectrum disorders 81
Cyclic diacyl thioureas enhance activity of corrector Lumacaftor on F508del‐CFTR 80
LEAD OPTIMIZATION OF MKT-077 ANALOGUES AS HSP70 ALLOSTERIC INHIBITORS COMBINED WITH F508DEL CFTR CORRECTORS: A MULTI DRUG APPROACH TO CONTRAST CYSTIC FIBROSIS 78
Comprehensive analysis of combinatorial pharmacological treatments to correct nonsense mutations in the cftr gene 78
Probing Allosteric Hsp70 Inhibitors by Molecular Modelling Studies to Expedite the Development of Novel Combined F508del CFTR Modulators 74
Rescue by elexacaftor-tezacaftor-ivacaftor of the G1244E cystic fibrosis mutation's stability and gating defects are dependent on cell background 74
Patient's dermal fibroblasts as disease markers for visceral myopathy 64
Simultaneous Quantification of Ivacaftor, Tezacaftor, and Elexacaftor in Cystic Fibrosis Patients’ Plasma by a Novel LC–MS/MS Method 62
Clinical Consequences and Functional Impact of the Rare S737F CFTR Variant and Its Responsiveness to CFTR Modulators 53
De novo variants in DENND5B cause a neurodevelopmental disorder 51
Virtual Drug Repositioning as a Tool to Identify Natural Small Molecules That Synergize with Lumacaftor in F508del-CFTR Binding and Rescuing 43
Therapeutic monitoring of Ivacaftor, Tezacaftor and Elexacaftor in patients with cystic fibrosis|Monitoraggio terapeutico di Ivacaftor, Tezacaftor e Elexacaftor in pazienti con fibrosi cistica 43
QUANTIFICATION OF IVACAFTOR, TEZACAFTOR, AND ELEXACAFTOR IN PLASMA OF CYSTIC FIBROSIS PATIENTS BY AN HPLC–MS/MS METHOD 42
Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators 41
Quantification of Ivacaftor, Tezacaftor and Elexacaftor in plasma of cystic fibrosis patients treated with Kaftrio by a validated liquid chromatography-tandem mass spectrometric (LC-MS/MS) method” 38
A Novel LC-MS/MS Method for the Measurement of Elexacaftor, Tezacaftor and Ivacaftor in Plasma, Dried Plasma Spot (DPS) and Whole Blood in Volumetric Absorptive Microsampling (VAMS) Devices 31
null 18
Structure-guided combination of novel CFTR correctors to improve the function of F508del-CFTR in airway epithelial cells 13
In silico, in vitro and ex vivo characterization of cystic fibrosis transmembrane conductance regulator pathogenic variants localized in the fourth intracellular loop and their rescue by modulators 10
Totale 1.425
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Categoria #
all - tutte 6.564
article - articoli 6.006
book - libri 0
conference - conferenze 558
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 13.128
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/202289 0 4 2 1 0 2 1 10 8 18 33 10
2022/2023157 8 12 5 10 22 10 4 14 27 1 35 9
2023/2024150 5 10 6 18 12 18 20 8 9 7 15 22
2024/2025696 15 28 27 38 32 74 43 166 58 75 72 68
2025/2026333 139 22 93 79 0 0 0 0 0 0 0 0
Totale 1.425